CA2589118A1 - Produit medical contenant un medicament peptidique de type glucagone a inhaler - Google Patents
Produit medical contenant un medicament peptidique de type glucagone a inhaler Download PDFInfo
- Publication number
- CA2589118A1 CA2589118A1 CA002589118A CA2589118A CA2589118A1 CA 2589118 A1 CA2589118 A1 CA 2589118A1 CA 002589118 A CA002589118 A CA 002589118A CA 2589118 A CA2589118 A CA 2589118A CA 2589118 A1 CA2589118 A1 CA 2589118A1
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- medical product
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- medicament dose
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- 229940127554 medical product Drugs 0.000 title claims abstract description 77
- 239000003814 drug Substances 0.000 title claims abstract description 73
- 230000002685 pulmonary effect Effects 0.000 title claims abstract description 29
- 108010088406 Glucagon-Like Peptides Proteins 0.000 title claims description 111
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims abstract description 189
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- DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 claims description 16
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- 101800000221 Glucagon-like peptide 2 Proteins 0.000 claims description 4
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Classifications
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0402976-5 | 2004-12-03 | ||
| SE0402976A SE0402976L (sv) | 2004-12-03 | 2004-12-03 | Medicinsk produkt |
| US11/049696 | 2005-02-04 | ||
| US11/049,696 US20060120969A1 (en) | 2004-12-03 | 2005-02-04 | Medical product for inhalation containing glucagon-like peptide-1 (GLP-1) |
| PCT/SE2005/001648 WO2006059939A1 (fr) | 2004-12-03 | 2005-11-02 | Produit medical contenant un medicament peptidique de type glucagone a inhaler |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2589118A1 true CA2589118A1 (fr) | 2006-06-08 |
Family
ID=36565328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002589118A Abandoned CA2589118A1 (fr) | 2004-12-03 | 2005-11-02 | Produit medical contenant un medicament peptidique de type glucagone a inhaler |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1827381A1 (fr) |
| KR (1) | KR20070095927A (fr) |
| AU (1) | AU2005310367A1 (fr) |
| CA (1) | CA2589118A1 (fr) |
| WO (1) | WO2006059939A1 (fr) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| SI1494732T1 (sl) | 2002-03-20 | 2008-08-31 | Mannking Corp | Inhalacijski aparat |
| US8921311B2 (en) | 2003-08-01 | 2014-12-30 | Mannkind Corporation | Method for treating hyperglycemia |
| EP1786784B1 (fr) | 2004-08-20 | 2010-10-27 | MannKind Corporation | Catalyse de la synthese de dicetopiperazine |
| KR101306384B1 (ko) | 2004-08-23 | 2013-09-09 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는디케토디옥산염 |
| AU2006290227B2 (en) | 2005-09-14 | 2012-08-02 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents |
| US20130172274A1 (en) | 2005-12-20 | 2013-07-04 | Duke University | Methods and compositions for delivering active agents with enhanced pharmacological properties |
| RU2403059C2 (ru) | 2006-02-22 | 2010-11-10 | Маннкайнд Корпорейшн | Способ улучшения фармацевтических свойств микрочастиц, содержащих дикетопиперазин и активный агент |
| EP2211842B1 (fr) * | 2007-10-24 | 2015-08-12 | MannKind Corporation | Une formulation de poudre sèche inhalable comprenant de glp-1 pour l'utilisation dans le traitement de l'hyperglycémie et du diabète par administration pulmonaire |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| KR101629154B1 (ko) | 2008-06-13 | 2016-06-21 | 맨카인드 코포레이션 | 건조 분말 흡입기 및 약물 투여 시스템 |
| DK2300083T3 (da) | 2008-06-20 | 2013-07-22 | Mannkind Corp | Interaktivt apparat og fremgangsmåde til realtids-profilering af inhalationsforsøg |
| CN105727261A (zh) | 2008-06-27 | 2016-07-06 | 杜克大学 | 包含弹性蛋白样肽的治疗剂 |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| MX2011007371A (es) | 2009-01-08 | 2011-09-06 | Mannkind Corp | Metodo para tratar la hiperglucemia con la molecula. |
| MX2011009512A (es) | 2009-03-11 | 2011-11-29 | Mannkind Corp | Aparato, sistema y metodo para medir la resistencia de un inhalador. |
| SG176738A1 (en) | 2009-06-12 | 2012-01-30 | Mannkind Corp | Diketopiperazine microparticles with defined specific surface areas |
| CA2778698A1 (fr) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | Appareil et methode de simulation d'efforts d'inhalation |
| BR112012033060A2 (pt) | 2010-06-21 | 2018-02-27 | Mannkind Corp | métodos de sistema de liberação de fármaco em pó seco |
| CN105667994B (zh) | 2011-04-01 | 2018-04-06 | 曼金德公司 | 用于药物药盒的泡罩包装 |
| WO2012174472A1 (fr) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | Microparticules de dicétopipérazine de capacité élevée |
| US9233159B2 (en) | 2011-10-24 | 2016-01-12 | Mannkind Corporation | Methods and compositions for treating pain |
| SG10201605800UA (en) | 2012-07-12 | 2016-09-29 | Mannkind Corp | Dry powder drug delivery system and methods |
| EP2911690A1 (fr) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Compositions et procédés de vaccin antigrippal inhalable |
| JP6523247B2 (ja) | 2013-03-15 | 2019-05-29 | マンカインド コーポレイション | 微結晶性ジケトピペラジン粒子の製造方法および乾燥粉末組成物の製造方法 |
| CN114848614A (zh) | 2013-07-18 | 2022-08-05 | 曼金德公司 | 热稳定性干粉药物组合物和方法 |
| CA2920488C (fr) | 2013-08-05 | 2022-04-26 | Mannkind Corporation | Appareil d'insufflation et procedes |
| WO2015148905A1 (fr) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Utilisation d'insuline à action ultrarapide |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9409496D0 (en) * | 1994-05-12 | 1994-06-29 | London Health Ass | Method for improving glycaemic control in diabetes |
| US6720407B1 (en) * | 1998-08-28 | 2004-04-13 | Eli Lilly And Company | Method for administering insulinotropic peptides |
| FI108518B (fi) * | 1999-04-23 | 2002-02-15 | Orion Yhtymae Oyj | Jauheinhalaattori yhdistelmälääkkeelle |
| WO2001000223A2 (fr) * | 1999-06-25 | 2001-01-04 | Minimed Inc. | Therapie anti diabete a agents multiples |
| US6528486B1 (en) * | 1999-07-12 | 2003-03-04 | Zealand Pharma A/S | Peptide agonists of GLP-1 activity |
| US20010012829A1 (en) * | 2000-01-11 | 2001-08-09 | Keith Anderson | Transepithelial delivery GLP-1 derivatives |
| SE518397C2 (sv) * | 2001-04-05 | 2002-10-01 | Microdrug Ag | Förfarande och anordning för frigörande av pulver och inhalatoranordning för administrering av medicinskt pulver |
| EP1448222A4 (fr) * | 2001-10-19 | 2006-05-17 | Lilly Co Eli | Melanges biphasiques de glp-1 et d'insuline |
| US20030182540A1 (en) * | 2002-03-21 | 2003-09-25 | International Business Machines Corporation | Method for limiting physical resource usage in a virtual tag allocation environment of a microprocessor |
| US6926422B2 (en) * | 2003-09-09 | 2005-08-09 | Azoteq (Pty) Ltd. | Flashlight |
-
2005
- 2005-11-02 CA CA002589118A patent/CA2589118A1/fr not_active Abandoned
- 2005-11-02 WO PCT/SE2005/001648 patent/WO2006059939A1/fr active Application Filing
- 2005-11-02 KR KR1020077015300A patent/KR20070095927A/ko not_active Application Discontinuation
- 2005-11-02 AU AU2005310367A patent/AU2005310367A1/en not_active Abandoned
- 2005-11-02 EP EP05801482A patent/EP1827381A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006059939A1 (fr) | 2006-06-08 |
| KR20070095927A (ko) | 2007-10-01 |
| EP1827381A1 (fr) | 2007-09-05 |
| AU2005310367A1 (en) | 2006-06-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |