CA2582046A1 - Halocombstatins and methods of synthesis thereof - Google Patents
Halocombstatins and methods of synthesis thereof Download PDFInfo
- Publication number
- CA2582046A1 CA2582046A1 CA002582046A CA2582046A CA2582046A1 CA 2582046 A1 CA2582046 A1 CA 2582046A1 CA 002582046 A CA002582046 A CA 002582046A CA 2582046 A CA2582046 A CA 2582046A CA 2582046 A1 CA2582046 A1 CA 2582046A1
- Authority
- CA
- Canada
- Prior art keywords
- stilbene
- mhz
- phosphate
- nmr
- cdc13
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
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- KJTULOVPMGUBJS-UHFFFAOYSA-N tert-butyl-[tert-butyl(diphenyl)silyl]oxy-diphenylsilane Chemical compound C=1C=CC=CC=1[Si](C=1C=CC=CC=1)(C(C)(C)C)O[Si](C(C)(C)C)(C=1C=CC=CC=1)C1=CC=CC=C1 KJTULOVPMGUBJS-UHFFFAOYSA-N 0.000 description 1
- CZDYPVPMEAXLPK-UHFFFAOYSA-N tetramethylsilane Chemical compound C[Si](C)(C)C CZDYPVPMEAXLPK-UHFFFAOYSA-N 0.000 description 1
- 231100001274 therapeutic index Toxicity 0.000 description 1
- 208000013066 thyroid gland cancer Diseases 0.000 description 1
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- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61288804P | 2004-09-24 | 2004-09-24 | |
| US60/612,888 | 2004-09-24 | ||
| US10/948,926 | 2004-09-24 | ||
| US10/948,926 US7223747B2 (en) | 2003-09-24 | 2004-09-24 | Halocombstatins and methods of synthesis thereof |
| PCT/US2005/033998 WO2006036743A2 (en) | 2004-09-24 | 2005-09-23 | Halocombstatins and methods of synthesis thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2582046A1 true CA2582046A1 (en) | 2006-04-06 |
Family
ID=36119428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002582046A Abandoned CA2582046A1 (en) | 2004-09-24 | 2005-09-23 | Halocombstatins and methods of synthesis thereof |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1802560A4 (ja) |
| JP (1) | JP2008514614A (ja) |
| AU (1) | AU2005289773A1 (ja) |
| CA (1) | CA2582046A1 (ja) |
| WO (1) | WO2006036743A2 (ja) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101085743B (zh) | 2006-06-06 | 2012-02-15 | 浙江大德药业集团有限公司 | 含氟烷氧基康普立停衍生物及制法和用途 |
| TW200819409A (en) | 2006-10-19 | 2008-05-01 | Univ Taipei Medical | Z-stilbenes derivatives and the pharmaceutical composition thereof |
| WO2016130969A1 (en) | 2015-02-13 | 2016-08-18 | George Robert Pettit | Silstatin compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1351912A2 (en) * | 2000-12-21 | 2003-10-15 | Cancer Research Ventures Limited | Substituted stilbenes, their reactions and anticancer activity |
| US6919324B2 (en) * | 2001-10-26 | 2005-07-19 | Oxigene, Inc. | Functionalized stilbene derivatives as improved vascular targeting agents |
| AU2002319899A1 (en) * | 2002-06-25 | 2004-01-06 | Raju Gokaraju Ganga | Novel resveratrol analogs |
-
2005
- 2005-09-23 EP EP05816139A patent/EP1802560A4/en not_active Withdrawn
- 2005-09-23 AU AU2005289773A patent/AU2005289773A1/en not_active Abandoned
- 2005-09-23 WO PCT/US2005/033998 patent/WO2006036743A2/en active Application Filing
- 2005-09-23 JP JP2007533629A patent/JP2008514614A/ja active Pending
- 2005-09-23 CA CA002582046A patent/CA2582046A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006036743A3 (en) | 2006-05-26 |
| AU2005289773A1 (en) | 2006-04-06 |
| WO2006036743A2 (en) | 2006-04-06 |
| EP1802560A4 (en) | 2010-03-31 |
| JP2008514614A (ja) | 2008-05-08 |
| EP1802560A2 (en) | 2007-07-04 |
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