CA2577995A1 - Peptide inhibitors of c-jun dimerization and uses thereof - Google Patents
Peptide inhibitors of c-jun dimerization and uses thereof Download PDFInfo
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- CA2577995A1 CA2577995A1 CA002577995A CA2577995A CA2577995A1 CA 2577995 A1 CA2577995 A1 CA 2577995A1 CA 002577995 A CA002577995 A CA 002577995A CA 2577995 A CA2577995 A CA 2577995A CA 2577995 A1 CA2577995 A1 CA 2577995A1
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- WVLBCYQITXONBZ-UHFFFAOYSA-N trimethyl phosphate Chemical compound COP(=O)(OC)OC WVLBCYQITXONBZ-UHFFFAOYSA-N 0.000 description 1
- 230000001228 trophic effect Effects 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 238000013042 tunel staining Methods 0.000 description 1
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 1
- 229910052721 tungsten Inorganic materials 0.000 description 1
- 239000010937 tungsten Substances 0.000 description 1
- 238000003160 two-hybrid assay Methods 0.000 description 1
- 241000292502 unclassified Enterovirus Species 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 241000007181 unidentified human coronavirus Species 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 238000002460 vibrational spectroscopy Methods 0.000 description 1
- 238000004846 x-ray emission Methods 0.000 description 1
- 229940051021 yellow-fever virus Drugs 0.000 description 1
- 229940118695 yersinia pestis Drugs 0.000 description 1
- 108700007675 zebrafish ompb Proteins 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60352504P | 2004-08-20 | 2004-08-20 | |
| US60/603,525 | 2004-08-20 | ||
| PCT/AU2005/001255 WO2006017913A1 (en) | 2004-08-20 | 2005-08-22 | Peptide inhibitors of c-jun dimerization and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2577995A1 true CA2577995A1 (en) | 2006-02-23 |
Family
ID=35907184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002577995A Abandoned CA2577995A1 (en) | 2004-08-20 | 2005-08-22 | Peptide inhibitors of c-jun dimerization and uses thereof |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20100029552A1 (enExample) |
| EP (1) | EP1793841B1 (enExample) |
| JP (1) | JP2008522954A (enExample) |
| AU (1) | AU2005274616A1 (enExample) |
| CA (1) | CA2577995A1 (enExample) |
| WO (1) | WO2006017913A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7270969B2 (en) | 1999-05-05 | 2007-09-18 | Phylogica Limited | Methods of constructing and screening diverse expression libraries |
| US7803765B2 (en) | 1999-05-05 | 2010-09-28 | Phylogica Limited | Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom |
| EP1754052B1 (en) * | 2004-06-03 | 2015-07-22 | Phylogica Limited | Peptide modulators of cellular phenotype and bi-nucleic acid fragment library |
| WO2007097923A2 (en) | 2006-02-20 | 2007-08-30 | Phylogica Limited | Method of constructing and screening libraries of peptide structures |
| AU2007299562A1 (en) | 2006-09-19 | 2008-03-27 | Phylogica Limited | Neuroprotective peptide inhibitors of AP-1 signaling and uses therefor |
| EP2170932A4 (en) | 2007-06-20 | 2012-10-10 | Phylogica Ltd | COMPOSITIONS AND APPLICATIONS THEREOF IN THE TREATMENT OF ACUTE ATOMIC SYNDROME (ARDS) AND ASSOCIATED CLINICAL ILLNESSES |
| CN103842809B (zh) * | 2011-10-07 | 2016-01-13 | 株式会社岛津制作所 | 质量分析数据解析方法以及装置 |
| EP2812349B1 (en) | 2012-02-10 | 2021-09-01 | Cambridge Enterprise Limited | Methods for the characterisation of interaction sites on target proteins |
| EP2991665A4 (en) | 2013-03-13 | 2016-11-09 | Harvard College | STACKED AND GRAFTED POLYPEPTIDES AND USES THEREOF |
| KR20160019547A (ko) | 2013-06-14 | 2016-02-19 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 안정화된 폴리펩티드 인슐린 수용체 조절제 |
| US9580758B2 (en) | 2013-11-12 | 2017-02-28 | Luc Montagnier | System and method for the detection and treatment of infection by a microbial agent associated with HIV infection |
| CN111620940A (zh) * | 2014-05-21 | 2020-09-04 | 哈佛大学的校长及成员们 | Ras抑制肽和其用途 |
| US10738597B2 (en) * | 2015-05-20 | 2020-08-11 | Halliburton Energy Services, Inc. | Frequency comb for downhole chemical sensing |
| GB201522618D0 (en) * | 2015-12-22 | 2016-02-03 | Phoremost Ltd | Methods of screening |
| KR20200064075A (ko) | 2017-09-07 | 2020-06-05 | 포그 파마슈티컬스 인코포레이티드 | 베타-카테닌 기능을 조절하는 제제 및 이의 방법 |
| CN113403304B (zh) * | 2018-05-25 | 2022-09-30 | 吉林大学 | 副溶血性弧菌特异性结合的多肽v2及其应用 |
| GB202203399D0 (en) * | 2022-03-11 | 2022-04-27 | Univ Bath | c-jun antagonist peptides |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5843698A (en) * | 1997-04-30 | 1998-12-01 | Universal Ventures | Deleteriously affecting members of a target species by exposure to a component of symbiont or food source of an adjoiner species that is symbiotic with the target species |
| US6074815A (en) * | 1999-03-08 | 2000-06-13 | Universal Ventures | Selection of test species for testing to identify components thereof that deleteriously affect a target species member |
| US7270969B2 (en) * | 1999-05-05 | 2007-09-18 | Phylogica Limited | Methods of constructing and screening diverse expression libraries |
| US6150127A (en) * | 1999-11-30 | 2000-11-21 | Universal Ventures | Causing a desirable change in a behavior pattern |
| US6560542B1 (en) * | 2000-01-24 | 2003-05-06 | The Cielo Institute | Algorithmic design of peptides for binding and/or modulation of the functions of receptors and/or other proteins |
| US7117096B2 (en) * | 2001-04-17 | 2006-10-03 | Abmaxis, Inc. | Structure-based selection and affinity maturation of antibody library |
-
2005
- 2005-08-22 EP EP05773610A patent/EP1793841B1/en not_active Expired - Lifetime
- 2005-08-22 CA CA002577995A patent/CA2577995A1/en not_active Abandoned
- 2005-08-22 JP JP2007526128A patent/JP2008522954A/ja active Pending
- 2005-08-22 US US11/660,713 patent/US20100029552A1/en not_active Abandoned
- 2005-08-22 AU AU2005274616A patent/AU2005274616A1/en not_active Abandoned
- 2005-08-22 WO PCT/AU2005/001255 patent/WO2006017913A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005274616A1 (en) | 2006-02-23 |
| WO2006017913A1 (en) | 2006-02-23 |
| JP2008522954A (ja) | 2008-07-03 |
| EP1793841A4 (en) | 2009-07-22 |
| EP1793841B1 (en) | 2013-04-03 |
| WO2006017913A9 (en) | 2007-04-19 |
| EP1793841A1 (en) | 2007-06-13 |
| WO2006017913B1 (en) | 2006-03-30 |
| US20100029552A1 (en) | 2010-02-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |