CA2577995A1 - Peptide inhibitors of c-jun dimerization and uses thereof - Google Patents

Peptide inhibitors of c-jun dimerization and uses thereof Download PDF

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Publication number
CA2577995A1
CA2577995A1 CA002577995A CA2577995A CA2577995A1 CA 2577995 A1 CA2577995 A1 CA 2577995A1 CA 002577995 A CA002577995 A CA 002577995A CA 2577995 A CA2577995 A CA 2577995A CA 2577995 A1 CA2577995 A1 CA 2577995A1
Authority
CA
Canada
Prior art keywords
seq
peptide
nucleic acid
sequence
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002577995A
Other languages
English (en)
French (fr)
Inventor
Paul Michael Watt
Mark Fear
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phylogica Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2577995A1 publication Critical patent/CA2577995A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002577995A 2004-08-20 2005-08-22 Peptide inhibitors of c-jun dimerization and uses thereof Abandoned CA2577995A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60352504P 2004-08-20 2004-08-20
US60/603,525 2004-08-20
PCT/AU2005/001255 WO2006017913A1 (en) 2004-08-20 2005-08-22 Peptide inhibitors of c-jun dimerization and uses thereof

Publications (1)

Publication Number Publication Date
CA2577995A1 true CA2577995A1 (en) 2006-02-23

Family

ID=35907184

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002577995A Abandoned CA2577995A1 (en) 2004-08-20 2005-08-22 Peptide inhibitors of c-jun dimerization and uses thereof

Country Status (6)

Country Link
US (1) US20100029552A1 (enExample)
EP (1) EP1793841B1 (enExample)
JP (1) JP2008522954A (enExample)
AU (1) AU2005274616A1 (enExample)
CA (1) CA2577995A1 (enExample)
WO (1) WO2006017913A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7803765B2 (en) 1999-05-05 2010-09-28 Phylogica Limited Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom
US7270969B2 (en) 1999-05-05 2007-09-18 Phylogica Limited Methods of constructing and screening diverse expression libraries
CA2568644C (en) * 2004-06-03 2015-11-24 Phylogica Limited Peptide modulators of cellular phenotype and bi-nucleic acid fragment library
DK1987178T3 (en) * 2006-02-20 2015-04-20 Phylogica Ltd Process for the construction and screening of peptide structure libraries
CA2663545A1 (en) * 2006-09-19 2008-03-27 Phylogica Limited Neuroprotective peptide inhibitors of ap-1 signaling and uses thereof
WO2008154700A1 (en) * 2007-06-20 2008-12-24 Phylogica Limited Compositions and uses thereof for the treatment of acute respiratory distress syndrome (ards) and clinical disorders associated with therewith
CN103842809B (zh) * 2011-10-07 2016-01-13 株式会社岛津制作所 质量分析数据解析方法以及装置
WO2013116903A1 (en) 2012-02-10 2013-08-15 Phylogica Limited Methods for the characterisation of interaction sites on target proteins
EP3782638A1 (en) 2013-03-13 2021-02-24 President and Fellows of Harvard College Stapled and stitched polypeptides and uses thereof
WO2014201370A1 (en) 2013-06-14 2014-12-18 President And Fellows Of Harvard College Stabilized polypeptide insulin receptor modulators
US9580758B2 (en) 2013-11-12 2017-02-28 Luc Montagnier System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
CN114805527A (zh) * 2014-05-21 2022-07-29 哈佛大学的校长及成员们 Ras抑制肽和其用途
WO2016186669A1 (en) * 2015-05-20 2016-11-24 Halliburton Energy Services, Inc. Frequency comb for downhole chemical sensing
GB201522618D0 (en) * 2015-12-22 2016-02-03 Phoremost Ltd Methods of screening
BR112020004555A2 (pt) 2017-09-07 2020-09-24 Fog Pharmaceuticals, Inc. agentes que modulam funções de beta-catenina e métodos dos mesmos
CN113403304B (zh) * 2018-05-25 2022-09-30 吉林大学 副溶血性弧菌特异性结合的多肽v2及其应用
GB202203399D0 (en) * 2022-03-11 2022-04-27 Univ Bath c-jun antagonist peptides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843698A (en) * 1997-04-30 1998-12-01 Universal Ventures Deleteriously affecting members of a target species by exposure to a component of symbiont or food source of an adjoiner species that is symbiotic with the target species
US6074815A (en) * 1999-03-08 2000-06-13 Universal Ventures Selection of test species for testing to identify components thereof that deleteriously affect a target species member
US7270969B2 (en) * 1999-05-05 2007-09-18 Phylogica Limited Methods of constructing and screening diverse expression libraries
US6150127A (en) * 1999-11-30 2000-11-21 Universal Ventures Causing a desirable change in a behavior pattern
US6560542B1 (en) * 2000-01-24 2003-05-06 The Cielo Institute Algorithmic design of peptides for binding and/or modulation of the functions of receptors and/or other proteins
US7117096B2 (en) * 2001-04-17 2006-10-03 Abmaxis, Inc. Structure-based selection and affinity maturation of antibody library

Also Published As

Publication number Publication date
EP1793841A1 (en) 2007-06-13
AU2005274616A1 (en) 2006-02-23
EP1793841A4 (en) 2009-07-22
US20100029552A1 (en) 2010-02-04
WO2006017913A1 (en) 2006-02-23
EP1793841B1 (en) 2013-04-03
WO2006017913B1 (en) 2006-03-30
WO2006017913A9 (en) 2007-04-19
JP2008522954A (ja) 2008-07-03

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JP5576610B2 (ja) ペプチド構造のライブラリーの構築およびスクリーニング方法
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US7803765B2 (en) Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom
US8063012B2 (en) Neuroprotective peptide inhibitors of AP-1 signaling and uses therefor
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Legal Events

Date Code Title Description
FZDE Discontinued