CA2571627C - Substituted aryl-amine derivatives and methods of use - Google Patents

Substituted aryl-amine derivatives and methods of use Download PDF

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Publication number
CA2571627C
CA2571627C CA2571627A CA2571627A CA2571627C CA 2571627 C CA2571627 C CA 2571627C CA 2571627 A CA2571627 A CA 2571627A CA 2571627 A CA2571627 A CA 2571627A CA 2571627 C CA2571627 C CA 2571627C
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Prior art keywords
compound
salt
phenyl
methyl
nitro
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Expired - Fee Related
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CA2571627A
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English (en)
French (fr)
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CA2571627A1 (en
Inventor
Chester Chenguang Yuan
Kevin Yang
Simon Van Der Plas
Babak Riahi
Michele Potashman
Vinod F. Patel
Rana Nomak
Aiwen Li
Qi Huang
Jean-Christophe Harmange
Benny C. Askew, Jr.
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Amgen Inc
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Amgen Inc
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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  • Endocrinology (AREA)
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CA2571627A 2004-07-22 2005-07-20 Substituted aryl-amine derivatives and methods of use Expired - Fee Related CA2571627C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US59054404P 2004-07-22 2004-07-22
US60/590,544 2004-07-22
US11/185,556 2005-07-19
US11/185,556 US7507748B2 (en) 2004-07-22 2005-07-19 Substituted aryl-amine derivatives and methods of use
PCT/US2005/025800 WO2006012374A1 (en) 2004-07-22 2005-07-20 Substituted aryl-amine derivatives and methods of use

Publications (2)

Publication Number Publication Date
CA2571627A1 CA2571627A1 (en) 2006-02-02
CA2571627C true CA2571627C (en) 2010-02-16

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CA2571627A Expired - Fee Related CA2571627C (en) 2004-07-22 2005-07-20 Substituted aryl-amine derivatives and methods of use

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US (2) US7507748B2 (enExample)
EP (1) EP1773817B1 (enExample)
JP (1) JP2008507539A (enExample)
AT (1) ATE440834T1 (enExample)
AU (1) AU2005267161B2 (enExample)
CA (1) CA2571627C (enExample)
DE (1) DE602005016261D1 (enExample)
ES (1) ES2331318T3 (enExample)
MX (1) MX2007000672A (enExample)
WO (1) WO2006012374A1 (enExample)

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US7507748B2 (en) * 2004-07-22 2009-03-24 Amgen Inc. Substituted aryl-amine derivatives and methods of use
CA2577550C (en) * 2004-08-25 2012-10-16 The University Of Chicago Use of the combination comprising temozolomide and tnf-alpha for treating glioblastoma
WO2009051244A1 (ja) 2007-10-18 2009-04-23 Takeda Pharmaceutical Company Limited 複素環化合物
WO2011161217A2 (en) 2010-06-23 2011-12-29 Palacký University in Olomouc Targeting of vegfr2
US9302991B2 (en) * 2010-10-18 2016-04-05 Raqualia Pharma Inc. Arylamide derivatives as TTX-S blockers
US9029553B2 (en) * 2011-02-14 2015-05-12 Council Of Scientific & Industrial Research 2-anilino nicotinyl linked 2-amino benzothiazole conjugates and process for the preparation thereof
EP2714941A4 (en) * 2011-05-24 2014-12-03 Wistar Inst COMPOSITIONS AND METHODS FOR MODULATING THE EFFECT OF THE EPSTEIN-BARR NUCLEAR ANTIGEN 1
KR101412794B1 (ko) * 2011-07-27 2014-07-01 보령제약 주식회사 혈관생성억제 작용을 갖는 신규한 화합물, 이의 제조방법 및 이를 포함하는 약학적 조성물
UA112897C2 (uk) 2012-05-09 2016-11-10 Байєр Фарма Акцієнгезелльшафт Біциклічно заміщені урацили та їх застосування для лікування і/або профілактики захворювань
WO2014058744A2 (en) 2012-10-09 2014-04-17 California Institute Of Technology In vivo and in vitro olefin cyclopropanation catalyzed by heme enzymes
WO2014058729A1 (en) * 2012-10-09 2014-04-17 California Institute Of Technology In vivo and in vitro carbene insertion and nitrene transfer reactions catalyzed by heme enzymes
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US20090143355A1 (en) 2009-06-04
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US8247430B2 (en) 2012-08-21
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