CA2566166C - Flavonols ameliores - Google Patents

Flavonols ameliores Download PDF

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Publication number
CA2566166C
CA2566166C CA2566166A CA2566166A CA2566166C CA 2566166 C CA2566166 C CA 2566166C CA 2566166 A CA2566166 A CA 2566166A CA 2566166 A CA2566166 A CA 2566166A CA 2566166 C CA2566166 C CA 2566166C
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CA
Canada
Prior art keywords
group
compound
compounds
flavonols
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2566166A
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English (en)
Other versions
CA2566166A1 (fr
Inventor
Spencer John Williams
Owen Llewellyn Woodman
Suwan Yap
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
YAP SU WAN
Original Assignee
YAP SU WAN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by YAP SU WAN filed Critical YAP SU WAN
Priority to CA2566166A priority Critical patent/CA2566166C/fr
Publication of CA2566166A1 publication Critical patent/CA2566166A1/fr
Application granted granted Critical
Publication of CA2566166C publication Critical patent/CA2566166C/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un composé de formule (I) : (voir la formule I) où R est sélectionné parmi le groupe consistant en : H, alkyle, alkényle, alkynyle, hétéroalkyle, cycloalkyle, hétérocycloalkyle, aryle, un hétéroaryle et acyle, chacun pouvant être facultativement substitué; R1 est un groupement organique capable d'être converti en groupe chargé; chaque X et Y est indépendamment sélectionné parmi le groupe consistant en H, halogène, -CN, -NO2, -CF3, -OCF3, alkyle, alkényle, alkynyle, haloalkyle, haloalkényle, hétéroalkyle, cycloalkyle, cycloalkényle, hétérocycloalkyle, hétérocycloalkényle, aryle, hétéroaryle, cycloalkylalkyle, hétérocycloalkylalkyle, arylalkyle, hétéroarylalkyle, arylalkényle, cycloalkylhétéroalkyle, arylhétéroalkyle, hétérocycloalkylhétéroalkyle, hétéroarylhétéroalkyle, hydroxy, hydroxyalkyle, alkoxy, alkoxyalkyle, alkoxyaryle, alkényloxy, alkynyloxy, cycloalkyloxy, hétérocycloalkyloxy, aryloxy, hétéroaryloxy, arylalkyloxy, phénoxy, benzyloxy, amino, alkylamino, aminoalkyle, acylamino, arylamino, sulfonylamino, sulfinylamino, -COOH, -COR2, -COOR2, -CONHR2, -NHCOR2, -NHCOOR2, -NHCONHR2, C(=NOH)R2, alkoxycarbonyle, alkylaminocarbonyle, sulfonyle, alkylsulfonyle, alkylsulfinyle, arylsulfonyle, arylsulfinyle, aminosulfonyle, SR2 et acyle, chacun pouvant être facultativement substitué; chaque R2 est sélectionné indépendamment du groupe consistant en : H, alkyle, alkényle, alkynyle, haloalkyle, hétéroalkyle, cycloalkyle, hétérocycloalkyle, aryle, hétéroaryle, cycloalkylalkyle, hétérocycloalkylalkyle, arylalkyle, hétéroarylalkyl et acyle, chacun pouvant être facultativement substitué; m est un entier sélectionné parmi de groupe comprenant 0, 1, 2, 3, 4 et 5; p est un entier sélectionné parmi de groupe comprenant 0, 1, 2 et 3 ou un de leur sel ou leur promédicament pharmaceutiquement acceptable.
CA2566166A 2006-10-30 2006-10-30 Flavonols ameliores Expired - Fee Related CA2566166C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2566166A CA2566166C (fr) 2006-10-30 2006-10-30 Flavonols ameliores

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA2566166A CA2566166C (fr) 2006-10-30 2006-10-30 Flavonols ameliores

Publications (2)

Publication Number Publication Date
CA2566166A1 CA2566166A1 (fr) 2008-04-30
CA2566166C true CA2566166C (fr) 2013-12-03

Family

ID=39367028

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2566166A Expired - Fee Related CA2566166C (fr) 2006-10-30 2006-10-30 Flavonols ameliores

Country Status (1)

Country Link
CA (1) CA2566166C (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101838252B (zh) * 2010-05-27 2016-05-04 北京德众万全医药科技有限公司 2-正丁基-5-取代氨基苯并呋喃及其制备方法
GB201017315D0 (en) * 2010-10-13 2010-11-24 Antoxis Ltd Compound

Also Published As

Publication number Publication date
CA2566166A1 (fr) 2008-04-30

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