CA2565993C - Sel d'acide 4-ou 5- aminosalicylique - Google Patents

Sel d'acide 4-ou 5- aminosalicylique Download PDF

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Publication number
CA2565993C
CA2565993C CA2565993A CA2565993A CA2565993C CA 2565993 C CA2565993 C CA 2565993C CA 2565993 A CA2565993 A CA 2565993A CA 2565993 A CA2565993 A CA 2565993A CA 2565993 C CA2565993 C CA 2565993C
Authority
CA
Canada
Prior art keywords
mesalamine
arginine
treatment
arginine salt
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2565993A
Other languages
English (en)
Other versions
CA2565993A1 (fr
Inventor
John L. Wallace
Giuseppe Cirino
Anna Sparatore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ANTIBE HOLDINGS Inc
Original Assignee
Antibe Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antibe Therapeutics Inc filed Critical Antibe Therapeutics Inc
Publication of CA2565993A1 publication Critical patent/CA2565993A1/fr
Application granted granted Critical
Publication of CA2565993C publication Critical patent/CA2565993C/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/64—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring the carbon skeleton being further substituted by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2565993A 2004-05-27 2005-05-27 Sel d'acide 4-ou 5- aminosalicylique Expired - Fee Related CA2565993C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04425384.7 2004-05-27
EP04425384 2004-05-27
PCT/CA2005/000818 WO2005115075A2 (fr) 2004-05-27 2005-05-27 Sel d'acide 4- ou 5- aminosalicylique

Publications (2)

Publication Number Publication Date
CA2565993A1 CA2565993A1 (fr) 2005-12-08
CA2565993C true CA2565993C (fr) 2011-08-16

Family

ID=34932520

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2565993A Expired - Fee Related CA2565993C (fr) 2004-05-27 2005-05-27 Sel d'acide 4-ou 5- aminosalicylique

Country Status (4)

Country Link
US (1) US7326809B2 (fr)
EP (1) EP1751096A4 (fr)
CA (1) CA2565993C (fr)
WO (1) WO2005115075A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050170019A1 (en) * 2003-10-22 2005-08-04 Fred Hutchinson Cancer Research Center Methods, compositions and devices for inducing stasis in cells
CN1901795B (zh) * 2003-10-22 2014-03-26 弗雷德哈钦森癌症研究中心 用于在细胞，组织，器官，和有机体中诱导停滞的方法，组合物和装置
US20050136125A1 (en) * 2003-10-22 2005-06-23 Roth Mark B. Methods, compositions and devices for inducing stasis in cells, tissues, organs, and organisms
AU2006236150A1 (en) * 2005-04-20 2006-10-26 Fred Hutchinson Cancer Research Center Methods, compositions and articles of manufacture for enhancing survivability of cells, tissues, organs, and organisms
WO2006127591A2 (fr) * 2005-05-23 2006-11-30 Nitromed, Inc. Sels renforçant l'oxyde nitrique organique de composes anti-inflammatoires non steroidiens, compositions et procedes d'utilisation
US7541384B2 (en) 2007-06-08 2009-06-02 Axcan Pharma Inc. Mesalamine suppository
US8436051B2 (en) 2007-06-08 2013-05-07 Aptalis Pharma Canada Inc. Mesalamine suppository
US8217083B2 (en) * 2007-06-08 2012-07-10 Aptalis Pharma Canada Inc. Mesalamine suppository
ITMI20071965A1 (it) * 2007-10-11 2009-04-12 Domenico Russo Composizione farmaceutica comprendente sucralfato e mesalazina
US10426765B2 (en) 2012-06-15 2019-10-01 Conaris Research Institute Ag Pharmaceutical composition containing nicotinic acid and/or nicotinamide and/or tryptophan for positively influencing the intestinal microbiota
SG11201604759UA (en) * 2013-12-13 2016-07-28 Conaris Res Inst Ag A pharmaceutical composition containing combinations of nicotinamide and 5-aminosalicylic acid for beneficially influencing the intestinal microbiota and/or treating gastrointestinal inflammation
WO2015086843A2 (fr) 2013-12-13 2015-06-18 Conaris Research Institute Ag Composition pharmaceutique contenant de l'acide nicotinique et/ou de la nicotinamide destinée à influencer de manière bénéfique les taux de lipide dans le sang en modifiant la microbiote intestinale

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3151196A1 (de) * 1981-12-23 1983-06-30 Kurt Heinz Prof. Dr. 7800 Freiburg Bauer Verfahren zur herstellung von gut loeslichen 5-aminosalicylsaeure-arzneimittelzubereitungen
EP0308665B1 (fr) * 1981-12-23 1993-04-14 Kurt H. Prof. Dr. Bauer Sels de l'acide 5-aminosalicylique et préparations pharmaceutiques qui les contiennent
US5703073A (en) * 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
US6271278B1 (en) * 1997-05-13 2001-08-07 Purdue Research Foundation Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties

Also Published As

Publication number Publication date
US20060003972A1 (en) 2006-01-05
EP1751096A2 (fr) 2007-02-14
CA2565993A1 (fr) 2005-12-08
EP1751096A4 (fr) 2009-01-07
US7326809B2 (en) 2008-02-05
WO2005115075A2 (fr) 2005-12-08
WO2005115075A3 (fr) 2007-11-08

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MKLA Lapsed

Effective date: 20170529