CA2565014A1 - Isolated nucleic acid molecules encoding a novel phosphoprotein-darpp-32, encoded protein and uses thereof - Google Patents

Isolated nucleic acid molecules encoding a novel phosphoprotein-darpp-32, encoded protein and uses thereof Download PDF

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Publication number
CA2565014A1
CA2565014A1 CA002565014A CA2565014A CA2565014A1 CA 2565014 A1 CA2565014 A1 CA 2565014A1 CA 002565014 A CA002565014 A CA 002565014A CA 2565014 A CA2565014 A CA 2565014A CA 2565014 A1 CA2565014 A1 CA 2565014A1
Authority
CA
Canada
Prior art keywords
darpp
therapeutic moiety
antibody
seq
dopamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002565014A
Other languages
English (en)
French (fr)
Inventor
Philip E. Brandish
Paul J. Acton
Nan Wei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2565014A1 publication Critical patent/CA2565014A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002565014A 2004-05-19 2005-05-17 Isolated nucleic acid molecules encoding a novel phosphoprotein-darpp-32, encoded protein and uses thereof Abandoned CA2565014A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57263404P 2004-05-19 2004-05-19
US60/572,634 2004-05-19
PCT/US2005/017356 WO2005113572A2 (en) 2004-05-19 2005-05-17 Isolated nucleic acid molecules encoding a novel phosphoprotein-darpp-32, encoded protein and uses thereof

Publications (1)

Publication Number Publication Date
CA2565014A1 true CA2565014A1 (en) 2005-12-01

Family

ID=35428910

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002565014A Abandoned CA2565014A1 (en) 2004-05-19 2005-05-17 Isolated nucleic acid molecules encoding a novel phosphoprotein-darpp-32, encoded protein and uses thereof

Country Status (3)

Country Link
EP (1) EP1756144A4 (de)
CA (1) CA2565014A1 (de)
WO (1) WO2005113572A2 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1103699A (en) * 1997-10-17 1999-05-10 Rockefeller University, The Use of an inhibitor of the dephosphorylation of darpp-32 for treating schizophrenia
IL160305A0 (en) * 2001-08-10 2004-07-25 Univ Rockefeller Compositions and methods for modulation of darpp-32 phosphorylation
KR20040066788A (ko) * 2001-08-31 2004-07-27 더 락커펠러 유니버시티 프스포다이에스터레이즈 활성 및 뇌에서프스포다이에스터레이즈 1b 매개되는 신호의 조절
CA2458968A1 (en) * 2001-08-31 2003-03-13 The Rockefeller University Method for classification of anti-psychotic drugs

Also Published As

Publication number Publication date
WO2005113572A3 (en) 2006-02-16
EP1756144A4 (de) 2008-08-20
WO2005113572A2 (en) 2005-12-01
EP1756144A2 (de) 2007-02-28

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Legal Events

Date Code Title Description
FZDE Discontinued