CA2564963A1 - Steroid prodrugs with androgenic effect - Google Patents

Steroid prodrugs with androgenic effect Download PDF

Info

Publication number
CA2564963A1
CA2564963A1 CA002564963A CA2564963A CA2564963A1 CA 2564963 A1 CA2564963 A1 CA 2564963A1 CA 002564963 A CA002564963 A CA 002564963A CA 2564963 A CA2564963 A CA 2564963A CA 2564963 A1 CA2564963 A1 CA 2564963A1
Authority
CA
Canada
Prior art keywords
group
beta
sulfamoyl benzoate
oxo
sulfamoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002564963A
Other languages
English (en)
French (fr)
Inventor
Ralf Wyrwa
Peter Droescher
Sven Ring
Walter Elger
Birgitt Schneider
Alexander Hillisch
Gudrun Reddersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering Aktiengesellschaft
Ralf Wyrwa
Peter Droescher
Sven Ring
Walter Elger
Birgitt Schneider
Alexander Hillisch
Gudrun Reddersen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft, Ralf Wyrwa, Peter Droescher, Sven Ring, Walter Elger, Birgitt Schneider, Alexander Hillisch, Gudrun Reddersen filed Critical Schering Aktiengesellschaft
Publication of CA2564963A1 publication Critical patent/CA2564963A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
CA002564963A 2004-05-21 2005-05-10 Steroid prodrugs with androgenic effect Abandoned CA2564963A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004025986.0 2004-05-21
DE102004025986A DE102004025986A1 (de) 2004-05-21 2004-05-21 Steroid-Prodrugs mit androgener Wirkung
PCT/EP2005/005256 WO2005113575A1 (de) 2004-05-21 2005-05-10 Steroid-prodrugs mit androgener wirkung

Publications (1)

Publication Number Publication Date
CA2564963A1 true CA2564963A1 (en) 2005-12-01

Family

ID=34968657

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002564963A Abandoned CA2564963A1 (en) 2004-05-21 2005-05-10 Steroid prodrugs with androgenic effect

Country Status (22)

Country Link
EP (1) EP1747229A1 (zh)
JP (1) JP2007538026A (zh)
CN (1) CN1993375A (zh)
AR (1) AR049547A1 (zh)
AU (1) AU2005245568A1 (zh)
BR (1) BRPI0510136A (zh)
CA (1) CA2564963A1 (zh)
CR (1) CR8785A (zh)
DE (1) DE102004025986A1 (zh)
EA (1) EA200602049A1 (zh)
EC (1) ECSP067028A (zh)
GT (1) GT200500122A (zh)
IL (1) IL179293A0 (zh)
MX (1) MXPA06013469A (zh)
NO (1) NO20065885L (zh)
PA (1) PA8633601A1 (zh)
PE (1) PE20060271A1 (zh)
SV (1) SV2006002123A (zh)
TW (1) TW200613317A (zh)
UY (1) UY28911A1 (zh)
WO (1) WO2005113575A1 (zh)
ZA (1) ZA200610769B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10027887A1 (de) 2000-05-31 2001-12-13 Jenapharm Gmbh Verbindungen mit einer Sulfonamidgruppe und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
US7534780B2 (en) 2004-05-21 2009-05-19 Bayer Schering Pharma Aktiengesellschaft Estradiol prodrugs
DE102005057224A1 (de) * 2005-11-29 2007-05-31 Bayer Schering Pharma Ag Prodrugs ERß-selektiver Substanzen, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
DE102005057408A1 (de) * 2005-11-30 2007-05-31 Bayer Schering Pharma Ag Sulfamoylsulfonat-Prodrugs
CN101708338B (zh) * 2008-12-26 2014-06-04 中国人民解放军军事医学科学院放射与辐射医学研究所 含甾体结构的前药及其高度分散制剂
CN102964417A (zh) * 2012-11-30 2013-03-13 华中药业股份有限公司 17-羟基四氢吡喃醚甾族化合物的合成方法
CN107556258B (zh) * 2017-08-22 2021-06-04 湖北江田精密化学有限公司 一种4-氨基-2-氯-5(1h-四唑基-5)苯磺酰胺的制备方法
EP3533619A1 (en) * 2018-03-02 2019-09-04 Basf Se Heat sensitive recording material and color developer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH545316A (de) * 1970-07-17 1973-12-15 Hoffmann La Roche Verfahren zur Herstellung von Acylderivaten
US5001234A (en) * 1987-04-16 1991-03-19 The Upjohn Company Cyclic hydrocarbons with an aminoalkyl sidechain
US5571933A (en) * 1994-11-17 1996-11-05 Duquesne University Of The Holy Ghost Derivatives of estra 1,3,5(10)triene-17-one, 3-amino compounds and their use
DE19712488A1 (de) * 1997-03-25 1998-10-01 Knoell Hans Forschung Ev Steroidsulfamate, Verfahren zu ihrer Herstellung und Anwendung derselben
DE10027887A1 (de) * 2000-05-31 2001-12-13 Jenapharm Gmbh Verbindungen mit einer Sulfonamidgruppe und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen

Also Published As

Publication number Publication date
WO2005113575A1 (de) 2005-12-01
GT200500122A (es) 2006-01-24
IL179293A0 (en) 2007-03-08
SV2006002123A (es) 2006-02-15
BRPI0510136A (pt) 2007-10-02
JP2007538026A (ja) 2007-12-27
CN1993375A (zh) 2007-07-04
AU2005245568A1 (en) 2005-12-01
PE20060271A1 (es) 2006-05-25
UY28911A1 (es) 2005-12-30
EA200602049A1 (ru) 2007-06-29
DE102004025986A1 (de) 2005-12-15
NO20065885L (no) 2006-12-19
CR8785A (es) 2007-02-05
EP1747229A1 (de) 2007-01-31
ECSP067028A (es) 2006-12-29
PA8633601A1 (es) 2006-07-03
AR049547A1 (es) 2006-08-16
TW200613317A (en) 2006-05-01
ZA200610769B (en) 2008-08-27
MXPA06013469A (es) 2007-01-23

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Legal Events

Date Code Title Description
FZDE Discontinued