CA2564654A1 - Identification and characterization of a subset of glioblastomas sensitive to treatment with imatinib - Google Patents

Identification and characterization of a subset of glioblastomas sensitive to treatment with imatinib Download PDF

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Publication number
CA2564654A1
CA2564654A1 CA002564654A CA2564654A CA2564654A1 CA 2564654 A1 CA2564654 A1 CA 2564654A1 CA 002564654 A CA002564654 A CA 002564654A CA 2564654 A CA2564654 A CA 2564654A CA 2564654 A1 CA2564654 A1 CA 2564654A1
Authority
CA
Canada
Prior art keywords
mammal
expression
responsive
phosphorylation
cell proliferative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002564654A
Other languages
English (en)
French (fr)
Inventor
Monica Nister
Daniel Hagerstrand
Goran Hesselager
Arne Ostman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ludwig Institute for Cancer Research Ltd
UPPSALA UNIVERSITY HOSPITAL
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0410883A external-priority patent/GB0410883D0/en
Priority claimed from GB0425257A external-priority patent/GB0425257D0/en
Application filed by Individual filed Critical Individual
Publication of CA2564654A1 publication Critical patent/CA2564654A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA002564654A 2004-05-14 2005-05-13 Identification and characterization of a subset of glioblastomas sensitive to treatment with imatinib Abandoned CA2564654A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0410883.3 2004-05-14
GB0410883A GB0410883D0 (en) 2004-05-14 2004-05-14 Organic compounds
GB0425257.3 2004-11-16
GB0425257A GB0425257D0 (en) 2004-11-16 2004-11-16 Organic compounds
PCT/EP2005/005269 WO2005113801A2 (en) 2004-05-14 2005-05-13 Identification and characterization of a subset of glioblastomas sensitive to treatment with imatinib

Publications (1)

Publication Number Publication Date
CA2564654A1 true CA2564654A1 (en) 2005-12-01

Family

ID=35295424

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002564654A Abandoned CA2564654A1 (en) 2004-05-14 2005-05-13 Identification and characterization of a subset of glioblastomas sensitive to treatment with imatinib

Country Status (9)

Country Link
US (1) US20080199855A1 (enExample)
EP (1) EP1756306A2 (enExample)
JP (1) JP2007536920A (enExample)
AU (1) AU2005245572B9 (enExample)
BR (1) BRPI0511088A (enExample)
CA (1) CA2564654A1 (enExample)
MX (1) MXPA06013079A (enExample)
RU (1) RU2006144122A (enExample)
WO (1) WO2005113801A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2132336A1 (en) * 2007-03-02 2009-12-16 Board of Regents, The University of Texas System Multigene assay to predict outcome in an individual with glioblastoma
BR112012004237A8 (pt) * 2009-08-25 2016-10-04 Berg Pharma Llc métodos para tratamento de um sarcoma usando um alterador epimetabólico (coenzima q10)
EA201691257A1 (ru) * 2011-06-02 2017-02-28 Олмак Дайэгностикс Лимитед Молекулярно-диагностический тест на рак
HK1214633A1 (zh) 2012-12-03 2016-07-29 Almac Diagnostics Limited 癌症的分子诊断测试
GB201409479D0 (en) 2014-05-28 2014-07-09 Almac Diagnostics Ltd Molecular diagnostic test for cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2829154B1 (fr) * 2001-09-05 2003-10-17 Assist Publ Hopitaux De Paris Nouveau procede de detection d'une mutation en phase de lecture dans une sequence codante et appareil pour sa mise en oeuvre
WO2003087404A1 (en) * 2002-04-17 2003-10-23 Novartis Ag Methods to predict patient responsiveness to tyrosine kinase inhibitors
JP4035600B2 (ja) * 2002-05-22 2008-01-23 国立大学法人 東京大学 イマチニブに対する感受性の判定方法

Also Published As

Publication number Publication date
AU2005245572B9 (en) 2009-01-29
RU2006144122A (ru) 2008-06-20
MXPA06013079A (es) 2007-10-08
US20080199855A1 (en) 2008-08-21
AU2005245572B2 (en) 2008-12-04
AU2005245572A1 (en) 2005-12-01
JP2007536920A (ja) 2007-12-20
EP1756306A2 (en) 2007-02-28
BRPI0511088A (pt) 2007-12-26
WO2005113801A2 (en) 2005-12-01
WO2005113801A3 (en) 2006-02-23

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Legal Events

Date Code Title Description
FZDE Discontinued