CA2562937A1 - Use of peptidic compounds for the prophylaxis and treatment of chronic headache - Google Patents
Use of peptidic compounds for the prophylaxis and treatment of chronic headache Download PDFInfo
- Publication number
- CA2562937A1 CA2562937A1 CA002562937A CA2562937A CA2562937A1 CA 2562937 A1 CA2562937 A1 CA 2562937A1 CA 002562937 A CA002562937 A CA 002562937A CA 2562937 A CA2562937 A CA 2562937A CA 2562937 A1 CA2562937 A1 CA 2562937A1
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- CA
- Canada
- Prior art keywords
- lower alkyl
- use according
- unsubstituted
- aryl
- heterocyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K31/16—Amides, e.g. hydroxamic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Immunology (AREA)
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US56268104P | 2004-04-16 | 2004-04-16 | |
| US60/562,681 | 2004-04-16 | ||
| PCT/EP2005/004047 WO2005099740A1 (en) | 2004-04-16 | 2005-04-15 | Use of peptidic compounds for the prophylaxis and treatment of chronic headache |
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| ES2185606T3 (es) | 2001-03-21 | 2003-05-01 | Sanol Arznei Schwarz Gmbh | Nuevo uso de una clase de compuestos peptidicos para tratamiento de la alodinia u otros tipos diferentes de dolor cronico o fantasma. |
| JP4664924B2 (ja) * | 2003-12-02 | 2011-04-06 | ウーツェーベー ファルマ ゲーエムベーハー | 中枢神経因性疼痛の治療のためのペプチド化合物の新規使用 |
| US20100256179A1 (en) * | 2004-03-26 | 2010-10-07 | Ucb Pharma Gmbh | Combination therapy for pain in painful diabetic neuropathy |
| US20070042969A1 (en) * | 2004-03-26 | 2007-02-22 | Srz Properties, Inc. | Combination therapy for pain in painful diabetic neuropathy |
| EP1579858A1 (en) * | 2004-03-26 | 2005-09-28 | Schwarz Pharma Ag | Novel use of peptide compounds for treating pain in painful diabetic neuropathy |
| EP1604655A1 (en) | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating pain in trigeminal neuralgia |
| PL1781276T3 (pl) * | 2004-08-27 | 2010-11-30 | Ucb Pharma Gmbh | Zastosowanie związków peptydowych do leczenia bólu związanego z rakiem kości, bólu indukowanego przez chemioterapię oraz nukleozydy |
| EP1642889A1 (en) * | 2004-10-02 | 2006-04-05 | Schwarz Pharma Ag | Improved synthesis scheme for lacosamide |
| US20060252749A1 (en) * | 2005-01-28 | 2006-11-09 | Srz Properties, Inc. | Lacosamide for add-on therapy of psychosis |
| US20070043120A1 (en) * | 2005-08-18 | 2007-02-22 | Bettina Beyreuther | Therapeutic combination for painful medical conditions |
| EP1754476A1 (en) * | 2005-08-18 | 2007-02-21 | Schwarz Pharma Ag | Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia |
| US7902401B2 (en) | 2006-12-14 | 2011-03-08 | Nps Pharmaceuticals, Inc. | Fluorinated compounds |
| JP2009539792A (ja) * | 2006-06-08 | 2009-11-19 | シュヴァルツ・ファーマ・アーゲー | 疼痛の医学的状態のための治療組合せ |
| EP1873527A1 (en) * | 2006-06-30 | 2008-01-02 | Schwarz Pharma Ag | Method for identifying CRMP modulators |
| WO2007144195A2 (en) | 2006-06-15 | 2007-12-21 | Schwarz Pharma Ag | Pharmaceutical composition with synergistic anticonvulsant effect |
| CN101466390B (zh) | 2006-06-15 | 2014-03-12 | 优时比制药有限公司 | 用于治疗难治性癫痫持续状态的肽类化合物 |
| CA2672494A1 (en) | 2006-12-14 | 2008-06-19 | Nps Pharmaceuticals, Inc. | Use of d-serine derivatives for the treatment of anxiety disorders |
| EP2435465B1 (en) * | 2009-05-29 | 2016-03-09 | Ruprecht-Karls-Universität Heidelberg | Methylglyoxal-scavenging compounds and their use for the prevention and treatment of pain and/or hyperalgesia |
| CA2774569A1 (en) * | 2009-09-23 | 2011-03-31 | The University Of North Carolina At Chapel Hill | Novel n-benzylamide substituted derivatives of 2-(acylamido)acetic acid and 2-(acylamido)propionic acids: potent neurological agents |
| MX2013005974A (es) | 2010-12-02 | 2013-07-29 | Ucb Pharma Gmbh | Formulacion de lacosamida de administracion una vez al dia. |
| EP2468261A1 (en) | 2010-12-02 | 2012-06-27 | UCB Pharma GmbH | Formulation of lacosamide |
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| DE2937698A1 (de) | 1979-09-18 | 1981-04-02 | A. Nattermann & Cie GmbH, 5000 Köln | N-propionylsarcosinanilide, deren herstellungsverfahren und arzneimittel auf deren basis |
| FR2480747A1 (fr) | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
| US4533657A (en) | 1981-07-24 | 1985-08-06 | Sterling Drug Inc. | Analgesic dipeptide amides and method of use and composition thereof |
| FR2518088B1 (fr) | 1981-12-16 | 1987-11-27 | Roques Bernard | Nouveaux derives d'aminoacides, et leur application therapeutique |
| US4510082A (en) | 1983-03-07 | 1985-04-09 | Eli Lilly And Company | Pharmacologically active peptides |
| JPH0680079B2 (ja) | 1984-11-09 | 1994-10-12 | エーザイ株式会社 | ポリペプチド |
| US5378729A (en) * | 1985-02-15 | 1995-01-03 | Research Corporation Technologies, Inc. | Amino acid derivative anticonvulsant |
| US5654301A (en) * | 1985-02-15 | 1997-08-05 | Research Corporation Technologies, Inc. | Amino acid derivative anticonvulsant |
| GB9103454D0 (en) | 1991-02-19 | 1991-04-03 | Pfizer Ltd | Therapeutic agents |
| US5656267A (en) | 1991-08-22 | 1997-08-12 | Sagen; Jacqueline | Implantable cells that alleviate chronic pain in humans |
| TW217417B (https=) | 1991-12-04 | 1993-12-11 | Manyu Seiyaku Kk | |
| US5585358A (en) * | 1993-07-06 | 1996-12-17 | Yissum Research Development Corporation Of The Hebrew University Of Jerusalem | Derivatives of valproic acid amides and 2-valproenoic acid amides, method of making and use thereof as anticonvulsant agents |
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-
2005
- 2005-04-15 KR KR1020067023956A patent/KR20070007931A/ko not_active Ceased
- 2005-04-15 EA EA200601912A patent/EA013591B1/ru not_active IP Right Cessation
- 2005-04-15 CN CN200580014652XA patent/CN1950101B/zh not_active Expired - Fee Related
- 2005-04-15 JP JP2007507771A patent/JP2007532607A/ja active Pending
- 2005-04-15 EP EP05729930A patent/EP1734980A1/en not_active Withdrawn
- 2005-04-15 WO PCT/EP2005/004047 patent/WO2005099740A1/en not_active Ceased
- 2005-04-15 CA CA002562937A patent/CA2562937A1/en not_active Abandoned
- 2005-04-15 BR BRPI0509903-0A patent/BRPI0509903A/pt not_active Application Discontinuation
- 2005-04-15 AU AU2005232395A patent/AU2005232395B2/en not_active Expired - Fee Related
- 2005-04-15 MX MXPA06011937A patent/MXPA06011937A/es not_active Application Discontinuation
- 2005-04-15 NZ NZ550482A patent/NZ550482A/en unknown
- 2005-04-15 US US10/599,976 patent/US8008351B2/en not_active Expired - Fee Related
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2006
- 2006-10-04 IL IL178442A patent/IL178442A0/en unknown
- 2006-10-04 ZA ZA200608241A patent/ZA200608241B/en unknown
- 2006-11-15 NO NO20065251A patent/NO20065251L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005099740A1 (en) | 2005-10-27 |
| JP2007532607A (ja) | 2007-11-15 |
| AU2005232395B2 (en) | 2010-09-09 |
| NO20065251L (no) | 2007-01-10 |
| IL178442A0 (en) | 2007-02-11 |
| KR20070007931A (ko) | 2007-01-16 |
| EA200601912A1 (ru) | 2007-04-27 |
| AU2005232395A1 (en) | 2005-10-27 |
| NZ550482A (en) | 2010-08-27 |
| CN1950101A (zh) | 2007-04-18 |
| BRPI0509903A (pt) | 2007-09-18 |
| US20080287545A1 (en) | 2008-11-20 |
| EP1734980A1 (en) | 2006-12-27 |
| MXPA06011937A (es) | 2007-01-26 |
| CN1950101B (zh) | 2011-03-30 |
| ZA200608241B (en) | 2008-04-30 |
| US8008351B2 (en) | 2011-08-30 |
| EA013591B1 (ru) | 2010-06-30 |
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