CA2560930A1 - Methods of protein fractionation using high performance tangential flow filtration - Google Patents
Methods of protein fractionation using high performance tangential flow filtration Download PDFInfo
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- CA2560930A1 CA2560930A1 CA002560930A CA2560930A CA2560930A1 CA 2560930 A1 CA2560930 A1 CA 2560930A1 CA 002560930 A CA002560930 A CA 002560930A CA 2560930 A CA2560930 A CA 2560930A CA 2560930 A1 CA2560930 A1 CA 2560930A1
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/147—Microfiltration
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/16—Feed pretreatment
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/58—Multistep processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/02—Inorganic material
- B01D71/024—Oxides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2315/00—Details relating to the membrane module operation
- B01D2315/10—Cross-flow filtration
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2315/00—Details relating to the membrane module operation
- B01D2315/16—Diafiltration
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/145—Ultrafiltration
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Genetics & Genomics (AREA)
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- Analytical Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Immunology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
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- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55013704P | 2004-03-04 | 2004-03-04 | |
| US60/550,137 | 2004-03-04 | ||
| US11/051,216 US20050197496A1 (en) | 2004-03-04 | 2005-02-04 | Methods of protein fractionation using high performance tangential flow filtration |
| US11/051,216 | 2005-02-04 | ||
| PCT/US2005/004332 WO2005091801A2 (en) | 2004-03-04 | 2005-02-08 | Methods of protein fractionation using high performance tangential flow filtration |
Publications (1)
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| CA2560930A1 true CA2560930A1 (en) | 2005-10-06 |
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Family Applications (1)
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| CA002560930A Abandoned CA2560930A1 (en) | 2004-03-04 | 2005-02-08 | Methods of protein fractionation using high performance tangential flow filtration |
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| US (1) | US20050197496A1 (enExample) |
| EP (1) | EP1732587A4 (enExample) |
| JP (1) | JP2007526302A (enExample) |
| KR (1) | KR20060129530A (enExample) |
| AU (1) | AU2005227064A1 (enExample) |
| CA (1) | CA2560930A1 (enExample) |
| IL (1) | IL177877A0 (enExample) |
| WO (1) | WO2005091801A2 (enExample) |
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| US20040226053A1 (en) * | 2000-10-13 | 2004-11-11 | Meade Harry M. | Methods of producing a target molecule in a transgenic animal and purification of the target molecule |
| NZ588616A (en) | 2004-09-30 | 2012-05-25 | Bayer Healthcare Llc | An apparatus for separating a protein of interest comprising a purification system integrated with a particle removal system |
| US20060130159A1 (en) * | 2004-12-09 | 2006-06-15 | Nick Masiello | Method of purifying recombinant MSP 1-42 derived from Plasmodium falciparum |
| US7531632B2 (en) * | 2006-02-16 | 2009-05-12 | Gtc Biotherapeutics, Inc. | Clarification of transgenic milk using depth filtration |
| WO2007103971A2 (en) * | 2006-03-07 | 2007-09-13 | Throwleigh Technologies, L.L.C. | Diafiltration system to fractionate protein mixtures |
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| CN101754977B (zh) * | 2007-07-17 | 2013-07-17 | 弗·哈夫曼-拉罗切有限公司 | 可变切向流过滤 |
| BRPI0919998A2 (pt) * | 2008-10-30 | 2017-06-06 | Paques Ip Bv | método para a filtração de um líquido de biorreator, módulo de membrana de fluxo cruzado, sistema de biorreator de membrana, e, uso de um fluxo descendente de líquido de um líquido de biorreator |
| US9055752B2 (en) | 2008-11-06 | 2015-06-16 | Intercontinental Great Brands Llc | Shelf-stable concentrated dairy liquids and methods of forming thereof |
| US20120029165A1 (en) * | 2010-07-16 | 2012-02-02 | Etzel Mark R | Methods and Compositions Involving Whey Protein Isolates |
| UA112972C2 (uk) | 2010-09-08 | 2016-11-25 | Інтерконтінентал Грейт Брендс ЛЛС | Рідкий молочний концентрат з високим вмістом сухих речовин |
| AU2011350895B2 (en) | 2010-12-30 | 2015-05-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Glycols as pathogen inactivating agents |
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| ES2842350T3 (es) * | 2013-03-19 | 2021-07-13 | Cmc Biologics As | Un procedimiento para la producción de un producto (por ejemplo, polipéptido) en un proceso de fermentación de cultivo celular continuo |
| MX384222B (es) | 2013-07-05 | 2025-03-14 | Lab Francais Du Fractionnement | Matriz de cromatografia de afinidad. |
| WO2015133972A1 (en) * | 2014-03-07 | 2015-09-11 | Agency For Science, Technology And Research | Apparatus and methods for fractionation of biological products |
| CA3140009C (en) | 2014-05-13 | 2023-09-05 | Amgen Inc. | Process control systems and methods for use with filters and filtration processes |
| CN114797474A (zh) * | 2014-05-21 | 2022-07-29 | 非链实验室 | 用于缓冲溶液交换的系统和方法 |
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| WO2015195453A2 (en) | 2014-06-16 | 2015-12-23 | Emd Millipore Corporation | Methods for increasing the capacity of flow-through processes |
| US10399039B2 (en) | 2014-06-25 | 2019-09-03 | Emd Millipore Corporation | Compact spiral-wound filter elements, modules and systems |
| CN105745009B (zh) | 2014-08-29 | 2018-09-28 | Emd 密理博公司 | 单程切向流过滤系统和具有渗余物的再循环的切向流过滤系统 |
| EP4147769B1 (en) | 2014-08-29 | 2025-05-21 | EMD Millipore Corporation | Processes for filtering liquids using single pass tangential flow filtration systems and tangential flow filtration systems with recirculation of retentate |
| DE102015108501A1 (de) * | 2015-05-29 | 2016-12-01 | Sartorius Stedim Biotech Gmbh | Verfahren und Filtrationsvorrichtung zur Herstellung einer konzentrierten Produktlösung |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
| CA3023486C (en) | 2016-06-09 | 2022-03-29 | Emd Millipore Corporation | Radial-path filter elements, systems and methods of using same |
| CN108017689A (zh) * | 2016-11-04 | 2018-05-11 | 郑州伊美诺生物技术有限公司 | 一种离心管及使用该离心管获取抗体蛋白的方法 |
| CN106474466B (zh) * | 2016-12-07 | 2018-04-13 | 申联生物医药（上海）股份有限公司 | 一种口蹄疫疫苗的制备方法 |
| WO2019173752A1 (en) | 2018-03-08 | 2019-09-12 | Repligen Corporation | Tangential flow depth filtration systems and methods of filtration using same |
| KR102819571B1 (ko) | 2018-05-25 | 2025-06-12 | 리플리겐 코포레이션 | 접선 유동 여과 시스템 및 방법 |
| EP3810310A1 (en) | 2018-06-21 | 2021-04-28 | Cytiva Sweden AB | System for filtration and associated method |
| WO2021030573A1 (en) * | 2019-08-13 | 2021-02-18 | Repligen Corporation | Control systems and methods for automated clarification of cell culture with high solids content |
| CN113559712A (zh) * | 2020-04-29 | 2021-10-29 | 上海药明生物技术有限公司 | 切向流过滤系统与方法 |
| JP7695344B2 (ja) | 2021-05-21 | 2025-06-18 | ケンブリッジ クロップス インコーポレイテッド． ドゥーイングビジネスアズ モリ | 絹フィブロイン溶液及び絹フィブロインを含む粉末を製造するためのシステム及び方法 |
| US11864569B2 (en) | 2021-08-16 | 2024-01-09 | Cambridge Crops, Inc. | Systems and methods for improving the performance of cereal using a silk fibroin solution and powders containing silk fibroin |
| EP4299156A1 (en) * | 2022-06-29 | 2024-01-03 | Sartorius Stedim Biotech GmbH | Tangential flow filtration/chromatography systems, use thereof, and methods of separation |
| FR3139999A1 (fr) * | 2022-09-22 | 2024-03-29 | Bucher Vaslin | Procédé de gestion du colmatage de membrane d’un dispositif de filtration tangentiel |
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| FR2787465A1 (fr) * | 1998-12-21 | 2000-06-23 | Transgene Sa | Procede d'inactivation des virus enveloppes dans une preparation virale de virus non enveloppes |
| US6984378B1 (en) * | 1999-02-26 | 2006-01-10 | Pfizer, Inc. | Method for the purification, recovery, and sporulation of cysts and oocysts |
| US7544500B2 (en) * | 1999-11-13 | 2009-06-09 | Talecris Biotherapeutics, Inc. | Process for the production of a reversibly inactive acidified plasmin composition |
| KR100788093B1 (ko) * | 2002-04-26 | 2007-12-21 | 제넨테크, 인크. | 단백질의 비친화성 정제 |
| US7264728B2 (en) * | 2002-10-01 | 2007-09-04 | Dow Corning Corporation | Method of separating components in a sample using silane-treated silica filter media |
| US20040162414A1 (en) * | 2002-11-22 | 2004-08-19 | Santora Ling C. | Method for reducing or preventing modification of a polypeptide in solution |
| RU2005129745A (ru) * | 2003-02-24 | 2006-03-20 | Джитиси Байотерапьютикс, Инк. (Us) | Способы и устройство проточной фильтрации вдоль потока |
| US20060130159A1 (en) * | 2004-12-09 | 2006-06-15 | Nick Masiello | Method of purifying recombinant MSP 1-42 derived from Plasmodium falciparum |
-
2005
- 2005-02-04 US US11/051,216 patent/US20050197496A1/en not_active Abandoned
- 2005-02-08 JP JP2007501797A patent/JP2007526302A/ja not_active Abandoned
- 2005-02-08 EP EP05713340A patent/EP1732587A4/en not_active Withdrawn
- 2005-02-08 WO PCT/US2005/004332 patent/WO2005091801A2/en not_active Ceased
- 2005-02-08 KR KR1020067020867A patent/KR20060129530A/ko not_active Withdrawn
- 2005-02-08 CA CA002560930A patent/CA2560930A1/en not_active Abandoned
- 2005-02-08 AU AU2005227064A patent/AU2005227064A1/en not_active Abandoned
-
2006
- 2006-09-04 IL IL177877A patent/IL177877A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005227064A1 (en) | 2005-10-06 |
| US20050197496A1 (en) | 2005-09-08 |
| JP2007526302A (ja) | 2007-09-13 |
| EP1732587A4 (en) | 2007-09-05 |
| IL177877A0 (en) | 2006-12-31 |
| KR20060129530A (ko) | 2006-12-15 |
| WO2005091801A3 (en) | 2006-06-15 |
| WO2005091801A2 (en) | 2005-10-06 |
| EP1732587A2 (en) | 2006-12-20 |
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