CA2558783A1 - Methode de synthese d'une formulation multiparticulaire de morphine orale - Google Patents
Methode de synthese d'une formulation multiparticulaire de morphine orale Download PDFInfo
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- CA2558783A1 CA2558783A1 CA002558783A CA2558783A CA2558783A1 CA 2558783 A1 CA2558783 A1 CA 2558783A1 CA 002558783 A CA002558783 A CA 002558783A CA 2558783 A CA2558783 A CA 2558783A CA 2558783 A1 CA2558783 A1 CA 2558783A1
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- Prior art keywords
- morphine
- hours
- use according
- formulation
- core
- Prior art date
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- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- CSMWJXBSXGUPGY-UHFFFAOYSA-L sodium dithionate Chemical compound [Na+].[Na+].[O-]S(=O)(=O)S([O-])(=O)=O CSMWJXBSXGUPGY-UHFFFAOYSA-L 0.000 description 1
- 229940005573 sodium fumarate Drugs 0.000 description 1
- 235000019294 sodium fumarate Nutrition 0.000 description 1
- RYYKJJJTJZKILX-UHFFFAOYSA-M sodium octadecanoate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC([O-])=O RYYKJJJTJZKILX-UHFFFAOYSA-M 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 210000000278 spinal cord Anatomy 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 230000001839 systemic circulation Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
- WEAPVABOECTMGR-UHFFFAOYSA-N triethyl 2-acetyloxypropane-1,2,3-tricarboxylate Chemical compound CCOC(=O)CC(C(=O)OCC)(OC(C)=O)CC(=O)OCC WEAPVABOECTMGR-UHFFFAOYSA-N 0.000 description 1
- 239000001069 triethyl citrate Substances 0.000 description 1
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 1
- 235000013769 triethyl citrate Nutrition 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6252597P | 1997-10-17 | 1997-10-17 | |
| US60/062,525 | 1997-10-17 | ||
| US08/977,965 US6066339A (en) | 1997-10-17 | 1997-11-25 | Oral morphine multiparticulate formulation |
| US08/977,965 | 1997-11-25 | ||
| CA002306333A CA2306333C (fr) | 1997-10-17 | 1997-12-05 | Formulation multiparticulaire de morphine orale |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002306333A Division CA2306333C (fr) | 1997-10-17 | 1997-12-05 | Formulation multiparticulaire de morphine orale |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2558783A1 true CA2558783A1 (fr) | 1999-04-29 |
| CA2558783C CA2558783C (fr) | 2013-01-22 |
Family
ID=37451511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2558783A Expired - Lifetime CA2558783C (fr) | 1997-10-17 | 1997-12-05 | Formulation orale multiparticulaire de morphine |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2558783C (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111504928A (zh) * | 2020-06-05 | 2020-08-07 | 深圳麦德凯诺医药科技有限公司 | 一种醋酸钙片溶出度的检测方法 |
-
1997
- 1997-12-05 CA CA2558783A patent/CA2558783C/fr not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111504928A (zh) * | 2020-06-05 | 2020-08-07 | 深圳麦德凯诺医药科技有限公司 | 一种醋酸钙片溶出度的检测方法 |
| CN111504928B (zh) * | 2020-06-05 | 2023-06-16 | 深圳麦德凯诺医药科技有限公司 | 一种醋酸钙片溶出度的检测方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2558783C (fr) | 2013-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20171205 |