CA2547670A1 - Treating infectious diseases using ice inhibitors - Google Patents
Treating infectious diseases using ice inhibitors Download PDFInfo
- Publication number
- CA2547670A1 CA2547670A1 CA002547670A CA2547670A CA2547670A1 CA 2547670 A1 CA2547670 A1 CA 2547670A1 CA 002547670 A CA002547670 A CA 002547670A CA 2547670 A CA2547670 A CA 2547670A CA 2547670 A1 CA2547670 A1 CA 2547670A1
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- Prior art keywords
- compound
- ice
- infection
- antibiotic
- ice inhibitor
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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| US52636203P | 2003-12-01 | 2003-12-01 | |
| US60/526,362 | 2003-12-01 | ||
| PCT/US2004/040345 WO2005053665A1 (en) | 2003-12-01 | 2004-12-01 | Treating infectious diseases using ice inhibitors |
Publications (1)
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| CA2547670A1 true CA2547670A1 (en) | 2005-06-16 |
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| JP (1) | JP2007513092A (https=) |
| CN (2) | CN101524351A (https=) |
| AU (1) | AU2004294343A1 (https=) |
| CA (1) | CA2547670A1 (https=) |
| WO (1) | WO2005053665A1 (https=) |
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| WO2005115362A1 (en) * | 2004-05-15 | 2005-12-08 | Vertex Pharmaceuticals Incorporated | Treating seizures using ice inhibitors |
| CA2567080A1 (en) * | 2004-05-27 | 2005-12-15 | Vertex Pharmaceuticals Incorporated | Ice inhibitors for the treatment of autoinflammatory diseases |
| CN101534824A (zh) * | 2006-11-17 | 2009-09-16 | 艾博特公司 | 作为化学活素受体拮抗剂的氨基吡咯烷 |
| WO2011094426A1 (en) | 2010-01-29 | 2011-08-04 | The United State Of America, As Represented By The Secretary, Department Of Health & Human Services | Caspase inhibitors |
| EP4225301A1 (en) * | 2020-10-07 | 2023-08-16 | Institut National de la Santé et de la Recherche Médicale | Treatments of coronavirus infections, cytokine release syndrome, cytokine storm syndrome, or diseases associated with excessive activation of inflammasomes by the use of inhibitors of inflammatory caspases |
| FR3114741A1 (fr) * | 2020-10-07 | 2022-04-08 | Etienne Jacotot | Traitements des infections à coronavirus, du syndrome de libération de cytokine, du syndrome de la tempête de cytokines ou des maladies associées à l'activation excessive des inflammasomes par l'utilisation d'inhibiteurs des caspases inflammatoires. |
| CN116041418A (zh) * | 2021-10-28 | 2023-05-02 | 苏州裕泰医药科技有限公司 | 羟脯氨酰基-丝氨酸化合物及其制备方法和应用 |
| CN116041419B (zh) * | 2021-10-28 | 2025-12-12 | 苏州裕泰医药科技有限公司 | 羟脯氨酰基-丝氨酸化合物及其制备和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6008217A (en) * | 1995-12-20 | 1999-12-28 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1β converting enzyme |
| US6204261B1 (en) * | 1995-12-20 | 2001-03-20 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1β Converting enzyme inhibitors |
| TWI243828B (en) * | 1998-03-19 | 2005-11-21 | Vertex Pharma | Inhibitors of caspases |
| US6201118B1 (en) * | 1998-08-19 | 2001-03-13 | Vertex Pharmaceuticals Inc. | Process for forming an N-acylated, N,N-containing bicyclic ring from piperazic acid or an ester thereof especially useful as an intermediate in the manufacture of a caspase inhibitor |
| PE20011350A1 (es) * | 2000-05-19 | 2002-01-15 | Vertex Pharma | PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE) |
| US20030096737A1 (en) * | 2001-04-19 | 2003-05-22 | Anita Diu-Hercend | Caspase inhibitors and uses thereof |
| EP1542768A1 (en) * | 2002-09-20 | 2005-06-22 | Alcon, Inc. | Use of cytokine synthesis inhibitors for the treatment of dry eye disorders |
| TW200509958A (en) * | 2003-02-14 | 2005-03-16 | Combinatorx Inc | Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines |
-
2004
- 2004-12-01 EP EP04812788A patent/EP1696894A1/en not_active Withdrawn
- 2004-12-01 CA CA002547670A patent/CA2547670A1/en not_active Abandoned
- 2004-12-01 WO PCT/US2004/040345 patent/WO2005053665A1/en not_active Ceased
- 2004-12-01 US US11/002,734 patent/US20050233974A1/en not_active Abandoned
- 2004-12-01 CN CN200910128642A patent/CN101524351A/zh active Pending
- 2004-12-01 AU AU2004294343A patent/AU2004294343A1/en not_active Abandoned
- 2004-12-01 CN CNA2004800398687A patent/CN1901892A/zh active Pending
- 2004-12-01 JP JP2006541503A patent/JP2007513092A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005053665A1 (en) | 2005-06-16 |
| EP1696894A1 (en) | 2006-09-06 |
| US20050233974A1 (en) | 2005-10-20 |
| CN1901892A (zh) | 2007-01-24 |
| AU2004294343A1 (en) | 2005-06-16 |
| JP2007513092A (ja) | 2007-05-24 |
| CN101524351A (zh) | 2009-09-09 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |