CA2547331A1 - Reseau de capteurs electro-optiques a base d'acides nucleiques et procede de detection d'analytes - Google Patents

Reseau de capteurs electro-optiques a base d'acides nucleiques et procede de detection d'analytes Download PDF

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Publication number
CA2547331A1
CA2547331A1 CA002547331A CA2547331A CA2547331A1 CA 2547331 A1 CA2547331 A1 CA 2547331A1 CA 002547331 A CA002547331 A CA 002547331A CA 2547331 A CA2547331 A CA 2547331A CA 2547331 A1 CA2547331 A1 CA 2547331A1
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CA
Canada
Prior art keywords
analyte
nucleic acid
sensor
fluorophore
sensors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002547331A
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English (en)
Inventor
Joel E. White
John S. Kauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tufts University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/303,548 external-priority patent/US7062385B2/en
Application filed by Individual filed Critical Individual
Publication of CA2547331A1 publication Critical patent/CA2547331A1/fr
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G01N21/783Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour for analysing gases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/0004Gaseous mixtures, e.g. polluted air
    • G01N33/0009General constructional details of gas analysers, e.g. portable test equipment
    • G01N33/0027General constructional details of gas analysers, e.g. portable test equipment concerning the detector
    • G01N33/0031General constructional details of gas analysers, e.g. portable test equipment concerning the detector comprising two or more sensors, e.g. a sensor array
    • G01N33/0034General constructional details of gas analysers, e.g. portable test equipment concerning the detector comprising two or more sensors, e.g. a sensor array comprising neural networks or related mathematical techniques
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6432Quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769Measurement method of reaction-produced change in sensor
    • G01N2021/7786Fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/0004Gaseous mixtures, e.g. polluted air
    • G01N33/0009General constructional details of gas analysers, e.g. portable test equipment
    • G01N33/0027General constructional details of gas analysers, e.g. portable test equipment concerning the detector
    • G01N33/0036General constructional details of gas analysers, e.g. portable test equipment concerning the detector specially adapted to detect a particular component
    • G01N33/0057Warfare agents or explosives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Artificial Intelligence (AREA)
  • Combustion & Propulsion (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mathematical Physics (AREA)
  • Food Science & Technology (AREA)
  • Plasma & Fusion (AREA)
  • Evolutionary Computation (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

L'invention concerne des procédés de détection, d'identification et de surveillance d'analytes en phase vapeur consistant à utiliser des réseaux de capteurs renfermant des acides nucléiques à étiquettes au fluorophore, séchés sur un substrat réagissant avec les analytes en phase vapeur. L'invention concerne également des procédés d'utilisation et de préparation de tels réseaux de capteurs.
CA002547331A 2002-11-25 2003-11-25 Reseau de capteurs electro-optiques a base d'acides nucleiques et procede de detection d'analytes Abandoned CA2547331A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42886902P 2002-11-25 2002-11-25
US10/303,548 US7062385B2 (en) 2002-11-25 2002-11-25 Intelligent electro-optical nucleic acid-based sensor array and method for detecting volatile compounds in ambient air
US10/303,548 2002-11-25
US60/428,869 2002-11-25
PCT/US2003/038186 WO2004048937A2 (fr) 2002-11-25 2003-11-25 Reseau de capteurs electro-optiques a base d'acides nucleiques et procede de detection d'analytes

Publications (1)

Publication Number Publication Date
CA2547331A1 true CA2547331A1 (fr) 2004-06-10

Family

ID=32396712

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002547331A Abandoned CA2547331A1 (fr) 2002-11-25 2003-11-25 Reseau de capteurs electro-optiques a base d'acides nucleiques et procede de detection d'analytes

Country Status (5)

Country Link
EP (1) EP1578896A4 (fr)
JP (1) JP2006507507A (fr)
AU (1) AU2003299576A1 (fr)
CA (1) CA2547331A1 (fr)
WO (1) WO2004048937A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114280023A (zh) * 2014-08-27 2022-04-05 加利福尼亚太平洋生物科学股份有限公司 集成分析器件阵列

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2890747B1 (fr) * 2005-09-15 2008-05-09 Flowgene Sa Methode et dispositif d'analyse de composes chimiques
FI20095501A0 (fi) 2009-05-04 2009-05-04 Pekka Haenninen Menetelmä näytteiden karakterisoimiseksi ja/tai määrittämiseksi
JP4818441B2 (ja) * 2010-01-25 2011-11-16 三井造船株式会社 蛍光測定装置及び蛍光測定方法
DE102011050389B4 (de) * 2011-05-16 2021-09-02 Presens - Precision Sensing Gmbh Sensoreinheit und Messverfahren
US9810631B2 (en) 2015-07-25 2017-11-07 Stem Arts Projects, Llc Wavelength scanning apparatus and method of use thereof
US9568429B1 (en) * 2015-07-25 2017-02-14 Stem Arts Projects, Llc Wavelength scanning apparatus and method of use thereof
DE102016200271A1 (de) * 2016-01-13 2017-07-13 Institut Dr. Foerster Gmbh & Co. Kg Vorrichtung zur Erzeugung und Messung einer Emission
WO2018081657A2 (fr) * 2016-10-27 2018-05-03 Koniku Inc. Systèmes de détection
KR101993438B1 (ko) * 2017-08-24 2019-06-27 지티엘코리아(주) 폭발물 탐지 시스템
JP7008653B2 (ja) 2019-02-07 2022-01-25 株式会社東芝 分子検出装置
CN113614516A (zh) * 2019-02-27 2021-11-05 金泰克斯公司 战术性化学检测器
CN111999427B (zh) * 2020-07-07 2022-06-28 安徽华能电缆集团有限公司 一种高阻燃无卤低烟低毒电力电缆的检测装置
CN116940839A (zh) * 2021-02-26 2023-10-24 株式会社香味醗酵 转换装置、预测模型制作装置、转换信息制作方法、预测模型制作方法及程序

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001234709A1 (en) * 2000-01-31 2001-08-07 Board Of Regents, The University Of Texas System Method of preparing a sensor array
US6649416B1 (en) * 2000-02-18 2003-11-18 Trustees Of Tufts College Intelligent electro-optical sensor array and method for analyte detection
AU2001247417A1 (en) * 2000-03-14 2001-09-24 Trustees Of Tufts College Cross-reactive sensors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114280023A (zh) * 2014-08-27 2022-04-05 加利福尼亚太平洋生物科学股份有限公司 集成分析器件阵列

Also Published As

Publication number Publication date
WO2004048937A2 (fr) 2004-06-10
AU2003299576A8 (en) 2004-06-18
WO2004048937A3 (fr) 2005-03-03
EP1578896A4 (fr) 2009-11-11
AU2003299576A1 (en) 2004-06-18
JP2006507507A (ja) 2006-03-02
EP1578896A2 (fr) 2005-09-28

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued