CA2546077C - Vaccine and method for treatment of neurodegenerative diseases - Google Patents
Vaccine and method for treatment of neurodegenerative diseases Download PDFInfo
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- A61K39/0005—Vertebrate antigens
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- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/416—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Neurosurgery (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US51862703P | 2003-11-12 | 2003-11-12 | |
| US60/518,627 | 2003-11-12 | ||
| US61096604P | 2004-09-20 | 2004-09-20 | |
| US60/610,966 | 2004-09-20 | ||
| PCT/IL2004/001037 WO2005046719A1 (en) | 2003-11-12 | 2004-11-11 | Vaccine and method for treatment of neurodegenerative diseases |
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| CA2546077A1 CA2546077A1 (en) | 2005-05-26 |
| CA2546077C true CA2546077C (en) | 2016-07-05 |
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| CA2546077A Expired - Fee Related CA2546077C (en) | 2003-11-12 | 2004-11-11 | Vaccine and method for treatment of neurodegenerative diseases |
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| US (3) | US20080085269A1 (https=) |
| EP (2) | EP1684797A1 (https=) |
| JP (1) | JP5456235B2 (https=) |
| AU (1) | AU2004288654B2 (https=) |
| CA (1) | CA2546077C (https=) |
| IL (2) | IL175535A (https=) |
| WO (1) | WO2005046719A1 (https=) |
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| ES2527760T3 (es) * | 1998-07-23 | 2015-01-29 | Yeda Research And Development Co., Ltd. | Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos |
| WO2005056574A2 (en) | 2003-12-09 | 2005-06-23 | Yeda Research And Development Co. Ltd. | Method and vaccine comprising copolymer 1 for treatment of psychiatric disorders |
| CA2546077C (en) | 2003-11-12 | 2016-07-05 | Yeda Research And Development Co. Ltd. | Vaccine and method for treatment of neurodegenerative diseases |
| US8193147B2 (en) | 2007-09-24 | 2012-06-05 | Hadasit Medical Research Services & Development Ltd. | Use of copolymer 1 for treatment of muscular dystrophy |
| WO2010019270A1 (en) * | 2008-08-14 | 2010-02-18 | Isis Pharmaceuticals, Inc. | Modulation of prion expression |
| USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
| US8759302B2 (en) * | 2010-03-16 | 2014-06-24 | Teva Pharmaceutical Industries, Ltd. | Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis |
| NZ703122A (en) | 2010-10-11 | 2016-06-24 | Teva Pharma | Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate |
| ES2601892T3 (es) | 2011-04-21 | 2017-02-16 | Mapi Pharma Limited | Pentapolímero aleatorio para el tratamiento de enfermedades autoinmunes |
| KR20140101730A (ko) | 2011-10-10 | 2014-08-20 | 테바 파마슈티컬 인더스트리즈 리미티드 | 글라티라머 아세테이트에 대한 임상 반응을 예측하는 데 유용한 단일 뉴클레오티드 다형성 |
| WO2013059322A2 (en) * | 2011-10-17 | 2013-04-25 | Lawrence Steinman | Amyloid beta peptide as a therapy for inflammation |
| EP3027205A4 (en) | 2013-07-28 | 2017-07-19 | Qantu Therapeutics, Inc. | Vaccine formulations that induce a th2 immune response |
| US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US10618963B2 (en) | 2014-03-12 | 2020-04-14 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| AU2015228372B2 (en) | 2014-03-12 | 2018-05-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| CN109600992A (zh) * | 2016-05-20 | 2019-04-09 | 西达-赛奈医疗中心 | 治疗或预防阿尔茨海默病和相关病况的方法 |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| HUE071047T2 (hu) | 2016-08-31 | 2025-07-28 | Mapi Pharma Ltd | Glatiramer-acetátot tartalmazó depórendszerek |
| CN110382052A (zh) | 2017-03-26 | 2019-10-25 | Mapi医药公司 | 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统 |
| SG11202103794QA (en) | 2018-11-21 | 2021-05-28 | Ionis Pharmaceuticals Inc | Compounds and methods for reducing prion expression |
| EP3725370A1 (en) | 2019-04-19 | 2020-10-21 | ImmunoBrain Checkpoint, Inc. | Modified anti-pd-l1 antibodies and methods and uses for treating a neurodegenerative disease |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| IL36670A (en) | 1971-04-21 | 1974-09-10 | Sela M | Therapeutic basic copolymers of amino acids |
| US6071970A (en) * | 1993-02-08 | 2000-06-06 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
| IL113812A (en) | 1994-05-24 | 2000-06-29 | Yeda Res & Dev | Copolymer-1 pharmaceutical compositions containing it and its use |
| US6717031B2 (en) | 1995-06-07 | 2004-04-06 | Kate Dora Games | Method for selecting a transgenic mouse model of alzheimer's disease |
| US6794414B1 (en) * | 1998-06-17 | 2004-09-21 | Yeda Research And Development Co. Ltd. | Method and compositions for treating diseases mediated by transglutaminase activity |
| WO2000005250A1 (en) | 1998-07-23 | 2000-02-03 | Yeda Research And Development Co., Ltd | Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides |
| JP2003521448A (ja) | 1998-07-23 | 2003-07-15 | ザ・プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ | 合成ペプチドおよび自己免疫疾患治療のための使用方法 |
| PT1248643E (pt) * | 2000-01-20 | 2005-10-31 | Yeda Res & Dev | Utilizacao de copolimero 1 e peptidos e polipeptidos congeneres e de celulas t tratadas co estes compostos para terapia neuroprotectora |
| DK1294390T3 (da) * | 2000-06-07 | 2006-04-03 | Yeda Res & Dev | Anvendelse af copolymer 1 og beslægtede peptider og polypeptider og T-celelr behandlet dermed til neurobeskyttelse mod glutamattoksicitet |
| IL148202A0 (en) * | 2000-06-20 | 2002-09-12 | Caprion Pharmaceuticals Inc | Copolymers and methods of treating prion-related diseases |
| MXPA03010327A (es) * | 2001-05-17 | 2004-02-17 | Applied Research Systems | USO DE OSTEOPONTINA PARA TRATAMIENTO Y/O PREVENCIoN DE ENFERMEDADES NEUROLoGICAS. |
| US7718699B1 (en) * | 2005-03-04 | 2010-05-18 | Broyles Robert H | Abscissic acid and derivatives thereof for the treatment of diseases |
| IL160105A0 (en) * | 2001-12-06 | 2004-06-20 | Yeda Res & Dev | Vaccine for treatment of motor neurone diseases |
| CA2546077C (en) | 2003-11-12 | 2016-07-05 | Yeda Research And Development Co. Ltd. | Vaccine and method for treatment of neurodegenerative diseases |
| US7220729B2 (en) * | 2004-05-10 | 2007-05-22 | Academia Sinica | Huntington's Disease Treatment |
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2004
- 2004-11-11 CA CA2546077A patent/CA2546077C/en not_active Expired - Fee Related
- 2004-11-11 US US10/578,899 patent/US20080085269A1/en not_active Abandoned
- 2004-11-11 JP JP2006539072A patent/JP5456235B2/ja not_active Expired - Fee Related
- 2004-11-11 EP EP04799345A patent/EP1684797A1/en not_active Withdrawn
- 2004-11-11 EP EP10012062.5A patent/EP2301569B1/en not_active Expired - Lifetime
- 2004-11-11 AU AU2004288654A patent/AU2004288654B2/en not_active Ceased
- 2004-11-11 WO PCT/IL2004/001037 patent/WO2005046719A1/en not_active Ceased
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2006
- 2006-05-10 IL IL175535A patent/IL175535A/en active IP Right Grant
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2011
- 2011-04-29 US US13/097,427 patent/US8828404B2/en not_active Expired - Fee Related
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2013
- 2013-01-24 IL IL224393A patent/IL224393B/en active IP Right Grant
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2014
- 2014-01-23 US US14/162,482 patent/US9517256B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP5456235B2 (ja) | 2014-03-26 |
| AU2004288654A1 (en) | 2005-05-26 |
| EP2301569A2 (en) | 2011-03-30 |
| US20140134196A1 (en) | 2014-05-15 |
| US8828404B2 (en) | 2014-09-09 |
| EP2301569A3 (en) | 2011-07-06 |
| US20110206706A1 (en) | 2011-08-25 |
| WO2005046719A1 (en) | 2005-05-26 |
| IL175535A0 (en) | 2006-09-05 |
| EP2301569B1 (en) | 2018-05-02 |
| EP1684797A1 (en) | 2006-08-02 |
| AU2004288654B2 (en) | 2009-12-03 |
| US9517256B2 (en) | 2016-12-13 |
| IL224393B (en) | 2018-06-28 |
| US20080085269A1 (en) | 2008-04-10 |
| CA2546077A1 (en) | 2005-05-26 |
| JP2007513079A (ja) | 2007-05-24 |
| IL175535A (en) | 2016-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20201112 |