CA2543926A1 - Use of an inhibitor of csf-1 activity for the treatment of inflammatory bowel disease - Google Patents
Use of an inhibitor of csf-1 activity for the treatment of inflammatory bowel disease Download PDFInfo
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- CA2543926A1 CA2543926A1 CA002543926A CA2543926A CA2543926A1 CA 2543926 A1 CA2543926 A1 CA 2543926A1 CA 002543926 A CA002543926 A CA 002543926A CA 2543926 A CA2543926 A CA 2543926A CA 2543926 A1 CA2543926 A1 CA 2543926A1
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- csf
- antibody
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- inhibitor
- activity
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/243—Colony Stimulating Factors
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
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| GBGB0325836.5A GB0325836D0 (en) | 2003-11-05 | 2003-11-05 | Biological products |
| GB0325836.5 | 2003-11-05 | ||
| PCT/GB2004/004652 WO2005046657A2 (en) | 2003-11-05 | 2004-11-03 | Use of an inhibitor of csf-1 activity for the treatment of inflammatory bowel disease |
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| CA2543926A1 true CA2543926A1 (en) | 2005-05-26 |
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| CA002543926A Abandoned CA2543926A1 (en) | 2003-11-05 | 2004-11-03 | Use of an inhibitor of csf-1 activity for the treatment of inflammatory bowel disease |
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| Country | Link |
|---|---|
| US (1) | US20070148172A1 (enExample) |
| EP (1) | EP1686970B1 (enExample) |
| JP (1) | JP2007510639A (enExample) |
| AU (1) | AU2004289098B2 (enExample) |
| CA (1) | CA2543926A1 (enExample) |
| ES (1) | ES2733818T3 (enExample) |
| GB (1) | GB0325836D0 (enExample) |
| WO (1) | WO2005046657A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10562970B2 (en) | 2010-05-04 | 2020-02-18 | Five Prime Therapeutics, Inc. | Antibodies that bind colony stimulating factor 1 receptor (CSF1R) |
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| KR101633520B1 (ko) * | 2008-03-14 | 2016-06-24 | 트랜스진 에스.에이. | Ｃｓｆ－１ｒ에 대한 항체 |
| WO2010062401A2 (en) * | 2008-11-26 | 2010-06-03 | Five Prime Therapeutics, Inc. | Treatment of osteolytic disorders and cancer using csf1r extracellular domain fusion molecules |
| WO2010062399A2 (en) * | 2008-11-26 | 2010-06-03 | Five Prime Therapeutics, Inc. | Csf1r extracellular domain fusion molecules and treatments using same |
| RS58693B1 (sr) | 2009-12-10 | 2019-06-28 | Hoffmann La Roche | Antitela koja poželjno vezuju ekstracelularni domen 4 humanog csf1r, i njihova primena |
| CA2789071C (en) | 2010-03-05 | 2018-03-27 | F. Hoffmann-La Roche Ag | Antibodies against human csf-1r and uses thereof |
| BR112012020372A8 (pt) | 2010-03-05 | 2018-01-02 | Hoffmann La Roche | anticorpo que se liga ao csf-1r humano, composição farmacêutica, ácido nucleico, vetores de expressão, célula hospedeira e método para a produção de um anticorpo recombinante |
| CA2841013C (en) | 2011-07-18 | 2020-04-21 | Morphosys Ag | Use of c-fms antagonists |
| US10023643B2 (en) | 2011-12-15 | 2018-07-17 | Hoffmann-La Roche Inc. | Antibodies against human CSF-1R and uses thereof |
| AR090263A1 (es) | 2012-03-08 | 2014-10-29 | Hoffmann La Roche | Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma |
| US20130302322A1 (en) | 2012-05-11 | 2013-11-14 | Five Prime Therapeutics, Inc. | Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r) |
| CN107759690A (zh) | 2012-08-31 | 2018-03-06 | 戊瑞治疗有限公司 | 用结合群落刺激因子1受体(csf1r)的抗体治疗病状的方法 |
| EP2984106B1 (en) | 2013-04-12 | 2019-03-06 | MorphoSys AG | Antibodies targeting m-csf |
| AR095882A1 (es) | 2013-04-22 | 2015-11-18 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9 |
| AR097584A1 (es) | 2013-09-12 | 2016-03-23 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano |
| SG11201610672YA (en) | 2014-06-23 | 2017-01-27 | Five Prime Therapeutics Inc | Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r) |
| KR102636539B1 (ko) | 2014-10-29 | 2024-02-13 | 파이브 프라임 테라퓨틱스, 인크. | 암에 대한 조합 요법 |
| BR112017013111A2 (pt) | 2014-12-22 | 2018-05-15 | Five Prime Therapeutics Inc | métodos de tratamento de um distúrbio e de tratamento da sinovite, uso de um anticorpo e anticorpo |
| SMT202100132T1 (it) | 2015-04-13 | 2021-05-07 | Five Prime Therapeutics Inc | Terapia di combinazione per il cancro |
| JP2018516933A (ja) * | 2015-06-02 | 2018-06-28 | ジェネンテック， インコーポレイテッド | 抗ｉｌ−３４抗体を使用して神経学的疾患を治療するための組成物及び方法 |
| EP3108897A1 (en) | 2015-06-24 | 2016-12-28 | F. Hoffmann-La Roche AG | Antibodies against human csf-1r for use in inducing lymphocytosis in lymphomas or leukemias |
| JP7138094B2 (ja) | 2016-08-25 | 2022-09-15 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | マクロファージ活性化剤と組み合わせた抗ｃｓｆ－１ｒ抗体の間欠投与 |
| WO2018119142A1 (en) | 2016-12-21 | 2018-06-28 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| JP7304287B2 (ja) | 2016-12-22 | 2023-07-06 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | 抗ｐｄ－ｌ１／ｐｄ１治療の不成功後の、抗ｐｄ－ｌ１抗体との組み合わせでの抗ｃｓｆ－１ｒ抗体を用いた腫瘍の治療 |
| WO2019055537A1 (en) | 2017-09-13 | 2019-03-21 | Five Prime Therapeutics, Inc. | ANTI-CSF1R AND ANTI-PD -1 ANTIBODY POLYTHERAPY FOR PANCREATIC CANCER |
| EP4337763A1 (en) | 2021-05-10 | 2024-03-20 | Institut Curie | Methods for the treatment of cancer, inflammatory diseases and autoimmune diseases |
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-
2003
- 2003-11-05 GB GBGB0325836.5A patent/GB0325836D0/en not_active Ceased
-
2004
- 2004-11-03 AU AU2004289098A patent/AU2004289098B2/en not_active Ceased
- 2004-11-03 EP EP04798381.2A patent/EP1686970B1/en not_active Expired - Lifetime
- 2004-11-03 JP JP2006537439A patent/JP2007510639A/ja active Pending
- 2004-11-03 CA CA002543926A patent/CA2543926A1/en not_active Abandoned
- 2004-11-03 ES ES04798381T patent/ES2733818T3/es not_active Expired - Lifetime
- 2004-11-03 WO PCT/GB2004/004652 patent/WO2005046657A2/en not_active Ceased
- 2004-11-03 US US10/578,384 patent/US20070148172A1/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10562970B2 (en) | 2010-05-04 | 2020-02-18 | Five Prime Therapeutics, Inc. | Antibodies that bind colony stimulating factor 1 receptor (CSF1R) |
| US11186646B2 (en) | 2010-05-04 | 2021-11-30 | Five Prime Therapeutics, Inc. | Antibodies that bind colony stimulating factor 1 receptor (CSF1R) |
Also Published As
| Publication number | Publication date |
|---|---|
| US20070148172A1 (en) | 2007-06-28 |
| GB0325836D0 (en) | 2003-12-10 |
| AU2004289098A1 (en) | 2005-05-26 |
| JP2007510639A (ja) | 2007-04-26 |
| AU2004289098B2 (en) | 2010-07-01 |
| ES2733818T3 (es) | 2019-12-03 |
| EP1686970A2 (en) | 2006-08-09 |
| WO2005046657A2 (en) | 2005-05-26 |
| WO2005046657A3 (en) | 2005-11-03 |
| EP1686970B1 (en) | 2019-04-10 |
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| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20121119 |