CA2542668C - A method for increasing cd8+ cytotoxic t cell reponses and for treating multiple sclerosis - Google Patents
A method for increasing cd8+ cytotoxic t cell reponses and for treating multiple sclerosis Download PDFInfo
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- CA2542668C CA2542668C CA2542668A CA2542668A CA2542668C CA 2542668 C CA2542668 C CA 2542668C CA 2542668 A CA2542668 A CA 2542668A CA 2542668 A CA2542668 A CA 2542668A CA 2542668 C CA2542668 C CA 2542668C
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Classifications
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/416—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/45—Bacterial antigens
- A61K40/453—Clostridium, e.g. Clostridium tetani
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/US2004/034448 WO2005037309A1 (en) | 2003-10-17 | 2004-10-18 | A method for increasing cd8+ cytotoxic t cell reponses and for treating multiple sclerosis |
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| CA2542668A1 CA2542668A1 (en) | 2005-04-28 |
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| JP2007509063A (ja) * | 2003-10-17 | 2007-04-12 | ベイラー カレッジ オブ メディスン | Ｃｄ８＋細胞傷害性ｔ細胞応答を増大させる方法、および多発性硬化症を処置するための方法 |
| ES2553192T3 (es) * | 2006-05-05 | 2015-12-04 | Opexa Therapeutics | Vacuna de células T |
| EP2050814A1 (en) * | 2007-10-17 | 2009-04-22 | Txcell | Compositions for treating multiple sclerosis |
| US9125850B2 (en) * | 2009-11-14 | 2015-09-08 | Cardio Vax, Llc | Immunomodulatory methods and systems for treatment and/or prevention of atherosclerosis |
| RU2435556C1 (ru) * | 2010-04-23 | 2011-12-10 | Владимир Васильевич Лантух | Способ лечения дистрофических заболеваний заднего полюса глаза |
| WO2013063713A1 (zh) * | 2011-10-31 | 2013-05-10 | 鑫品生医科技股份有限公司 | 诱发产生综合免疫细胞的方法 |
| CN105085615A (zh) * | 2014-05-23 | 2015-11-25 | 上海市普陀区中心医院 | 一种多肽序列及其应用 |
| CN105085616A (zh) * | 2014-05-23 | 2015-11-25 | 上海市普陀区中心医院 | 一种氨基酸序列及其应用 |
| KR20190124214A (ko) * | 2017-01-20 | 2019-11-04 | 아타라 바이오테라퓨틱스 인크. | 자가 t 세포를 사용하여 다발성 경화증을 치료하는 방법 |
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| CA2330458A1 (en) | 1998-04-29 | 1999-11-04 | Georgetown University | Methods of identifying and using hla binding compounds as hla-agonists and antagonists |
| PT1407004E (pt) * | 2001-05-15 | 2009-08-31 | Ortho Mcneil Janssen Pharm | Iniciação ex-vivo para produção de linfócitos t citotóxicos específicos de ligando-cd40 para tratar doenças autoimunes e alérgicas |
| US7658926B2 (en) * | 2001-09-14 | 2010-02-09 | Opexa Pharmaceuticals, Inc. | Autologous T-cell vaccines materials and methods |
| IL164376A0 (en) | 2002-04-03 | 2005-12-18 | Applied Research Systems | Ox4or binding agents, their preparation and pharmaceutical compositions containing them |
| JP2007509063A (ja) * | 2003-10-17 | 2007-04-12 | ベイラー カレッジ オブ メディスン | Ｃｄ８＋細胞傷害性ｔ細胞応答を増大させる方法、および多発性硬化症を処置するための方法 |
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| AU2004281817A1 (en) | 2005-04-28 |
| BRPI0415519A (pt) | 2006-12-26 |
| US20100183546A1 (en) | 2010-07-22 |
| EP1677821B1 (en) | 2013-02-27 |
| IL174935A (en) | 2012-01-31 |
| AU2004281817B2 (en) | 2010-07-22 |
| NZ546552A (en) | 2009-10-30 |
| CN1893971A (zh) | 2007-01-10 |
| CA2542668A1 (en) | 2005-04-28 |
| US20080107664A1 (en) | 2008-05-08 |
| EP1677821A1 (en) | 2006-07-12 |
| JP2007509063A (ja) | 2007-04-12 |
| IL174935A0 (en) | 2006-08-20 |
| WO2005037309A1 (en) | 2005-04-28 |
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