CA2537669C - Inhibiteurs des nucleosides phosphorylases et nucleosidases pour traiter le cancer - Google Patents

Inhibiteurs des nucleosides phosphorylases et nucleosidases pour traiter le cancer Download PDF

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Publication number
CA2537669C
CA2537669C CA2537669A CA2537669A CA2537669C CA 2537669 C CA2537669 C CA 2537669C CA 2537669 A CA2537669 A CA 2537669A CA 2537669 A CA2537669 A CA 2537669A CA 2537669 C CA2537669 C CA 2537669C
Authority
CA
Canada
Prior art keywords
hydroxy
methyl
deazaadenin
pyrrolidine
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2537669A
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English (en)
Other versions
CA2537669A1 (fr
Inventor
Vern L. Schramm
Chandan Guha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Albert Einstein College of Medicine
Original Assignee
Albert Einstein College of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Albert Einstein College of Medicine filed Critical Albert Einstein College of Medicine
Priority to CA2537669A priority Critical patent/CA2537669C/fr
Publication of CA2537669A1 publication Critical patent/CA2537669A1/fr
Application granted granted Critical
Publication of CA2537669C publication Critical patent/CA2537669C/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2537669A 2006-02-24 2006-02-24 Inhibiteurs des nucleosides phosphorylases et nucleosidases pour traiter le cancer Expired - Fee Related CA2537669C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2537669A CA2537669C (fr) 2006-02-24 2006-02-24 Inhibiteurs des nucleosides phosphorylases et nucleosidases pour traiter le cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA2537669A CA2537669C (fr) 2006-02-24 2006-02-24 Inhibiteurs des nucleosides phosphorylases et nucleosidases pour traiter le cancer

Publications (2)

Publication Number Publication Date
CA2537669A1 CA2537669A1 (fr) 2007-08-24
CA2537669C true CA2537669C (fr) 2015-08-11

Family

ID=38433809

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2537669A Expired - Fee Related CA2537669C (fr) 2006-02-24 2006-02-24 Inhibiteurs des nucleosides phosphorylases et nucleosidases pour traiter le cancer

Country Status (1)

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CA (1) CA2537669C (fr)

Also Published As

Publication number Publication date
CA2537669A1 (fr) 2007-08-24

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Effective date: 20200224