CA2533113A1 - Fragments solubles de la glycoproteine de spicule sras-cov - Google Patents

Fragments solubles de la glycoproteine de spicule sras-cov Download PDF

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Publication number
CA2533113A1
CA2533113A1 CA002533113A CA2533113A CA2533113A1 CA 2533113 A1 CA2533113 A1 CA 2533113A1 CA 002533113 A CA002533113 A CA 002533113A CA 2533113 A CA2533113 A CA 2533113A CA 2533113 A1 CA2533113 A1 CA 2533113A1
Authority
CA
Canada
Prior art keywords
thr
ser
leu
phe
val
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002533113A
Other languages
English (en)
Inventor
Dimiter S. Dimitrov
Xiaodong Xiao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institutes of Health NIH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2533113A1 publication Critical patent/CA2533113A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1002Coronaviridae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/20011Coronaviridae
    • C12N2770/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002533113A 2003-07-21 2004-07-20 Fragments solubles de la glycoproteine de spicule sras-cov Abandoned CA2533113A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US48916603P 2003-07-21 2003-07-21
US60/489,166 2003-07-21
US52464203P 2003-11-25 2003-11-25
US60/524,642 2003-11-25
PCT/US2004/023345 WO2005010034A1 (fr) 2003-07-21 2004-07-20 Fragments solubles de la glycoproteine de spicule sras-cov

Publications (1)

Publication Number Publication Date
CA2533113A1 true CA2533113A1 (fr) 2005-02-03

Family

ID=34107787

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002533113A Abandoned CA2533113A1 (fr) 2003-07-21 2004-07-20 Fragments solubles de la glycoproteine de spicule sras-cov

Country Status (5)

Country Link
EP (1) EP1648927A1 (fr)
AU (1) AU2004259750A1 (fr)
CA (1) CA2533113A1 (fr)
TW (1) TW200510450A (fr)
WO (1) WO2005010034A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060240515A1 (en) * 2003-07-21 2006-10-26 Dimitrov Dimiter S Soluble fragments of the SARS-CoV spike glycoprotein
WO2005027963A2 (fr) * 2003-09-15 2005-03-31 The United States Of America As Represented By Thesecretary Of Health And Human Services, Nih Procedes et compositions permettant de generer une reponse immunitaire protectrice contre sars-cov
PT2261376E (pt) * 2003-11-04 2013-09-23 Univ Tulane Método para prevenir a fusão vírus:células inibindo a função da região de iniciação de fusão em vírus de rna tendo proteínas do invólucro fusogénicas de membrana de classe i
CA2548942C (fr) * 2003-12-05 2013-10-15 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Health Anticorps monoclonaux anti-sars
WO2006071250A2 (fr) * 2004-04-05 2006-07-06 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Fragments solubles de la glycoproteine de spicule de cov-sras
TWI293957B (en) * 2004-07-21 2008-03-01 Healthbanks Biotech Co Ltd A superantigen fusion protein and the use thereof
EP1749833A1 (fr) 2005-08-05 2007-02-07 Healthbanks Biotech Co., Ltd. Superantigènes dérivés de la protéine à pointe E2 du coronavirus du SRAS
US8222204B2 (en) 2006-05-03 2012-07-17 The Administrators of the Tulane Educational Fund and Autoimmune Technologies, LLC Influenza inhibiting compositions and methods
KR101719135B1 (ko) 2007-06-25 2017-03-23 더 어드미니스트레이터즈 오브 더 튜래인 어듀케이셔널 훤드 인플루엔자를 억제하는 조성물 및 방법
CN113264991B (zh) * 2020-01-31 2023-05-16 上海桀蒙生物技术有限公司 病毒疫苗的制备方法及药物组合物
HUE058338T2 (hu) 2020-02-20 2022-07-28 Euroimmun Medizinische Labordiagnostika Ag Eljárás és reagensek SARS-COV-2 diagnózisára
US10822379B1 (en) * 2020-03-12 2020-11-03 University of Pittsburgh—of the Commonwealth System of Higher Education Molecules that bind to SARS-CoV-2
WO2021195089A1 (fr) * 2020-03-23 2021-09-30 Sorrento Therapeutics, Inc. Protéines de fusion de l'antigène fc-coronavirus et acides nucléiques, vecteurs, compositions et procédés d'utilisation associés
US20230106770A1 (en) * 2020-04-06 2023-04-06 Phylex Biosciences, Inc. Reagents and methods for preventing, treating or limiting severe acute respiratory syndrome (SARS) coronavirus infection
EP3892298A1 (fr) * 2020-04-09 2021-10-13 PreviPharma Consulting GmbH Épitopes ayant une homologie de séquence avec la sous-unité de protéine de spicule de coronavirus et leurs utilisations
CN113527444B (zh) * 2020-04-13 2022-12-27 中国科学院微生物研究所 与新型冠状病毒的抗体有效结合的表位
CN111995675B (zh) * 2020-05-15 2021-03-23 潍坊医学院 一种针对新冠病毒SARS-CoV-2棘突蛋白RBD区的单克隆抗体及其应用
CN113797326B (zh) * 2020-06-17 2024-01-19 上海君实生物医药科技股份有限公司 一种预防冠状病毒引起疾病的疫苗
EP3943944A1 (fr) * 2020-07-24 2022-01-26 Consejo Superior de Investigaciones Científicas (CSIC) Procédé multiplexé de cytométrie en flux pour la détection d'anticorps sars-cov-2
KR20230084469A (ko) 2020-08-04 2023-06-13 애보트 라피드 다이어그노스틱스 인터내셔널 언리미티드 컴퍼니 Sars-cov-2를 검출하기 위한 검정법
CN114057842A (zh) * 2020-08-07 2022-02-18 清华大学 一种预防新型冠状病毒肺炎covid-19的多肽、免疫原性偶联物及其用途
CN113698487B (zh) * 2021-08-16 2022-08-19 中国科学院微生物研究所 抗人ace2单克隆抗体及其应用
CN113633764B (zh) * 2021-09-02 2024-05-14 中国食品药品检定研究院 一种含佐剂的新冠dna疫苗

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2135201A1 (fr) * 1992-05-08 1993-11-25 Timothy J. Miller Vaccin universel contre le coronavirus

Also Published As

Publication number Publication date
EP1648927A1 (fr) 2006-04-26
TW200510450A (en) 2005-03-16
WO2005010034A1 (fr) 2005-02-03
AU2004259750A1 (en) 2005-02-03
AU2004259750A2 (en) 2005-02-03

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued