CA2526887A1 - Variants d'epissage d'une sous-unite humaine alpha2delta-2 des canaux calciques dependants d'un potentiel d'action appelee -alpha2delta2-a et alpha2delta2-b - Google Patents

Variants d'epissage d'une sous-unite humaine alpha2delta-2 des canaux calciques dependants d'un potentiel d'action appelee -alpha2delta2-a et alpha2delta2-b Download PDF

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Publication number
CA2526887A1
CA2526887A1 CA002526887A CA2526887A CA2526887A1 CA 2526887 A1 CA2526887 A1 CA 2526887A1 CA 002526887 A CA002526887 A CA 002526887A CA 2526887 A CA2526887 A CA 2526887A CA 2526887 A1 CA2526887 A1 CA 2526887A1
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CA
Canada
Prior art keywords
subunit
sequence
voltage
calcium channel
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002526887A
Other languages
English (en)
Inventor
Jayashree Aiyar
Charles Jay Cohen
Mark Edward Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck & Co., Inc.
Jayashree Aiyar
Charles Jay Cohen
Mark Edward Williams
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co., Inc., Jayashree Aiyar, Charles Jay Cohen, Mark Edward Williams filed Critical Merck & Co., Inc.
Publication of CA2526887A1 publication Critical patent/CA2526887A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • G01N33/5017—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity for testing neoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002526887A 2003-04-18 2004-04-16 Variants d'epissage d'une sous-unite humaine alpha2delta-2 des canaux calciques dependants d'un potentiel d'action appelee -alpha2delta2-a et alpha2delta2-b Abandoned CA2526887A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46382603P 2003-04-18 2003-04-18
US60/463,826 2003-04-18
PCT/US2004/012045 WO2004094604A2 (fr) 2003-04-18 2004-04-16 Variants d'epissage d'une sous-unite humaine alpha2delta-2 des canaux calciques dependants d'un potentiel d'action appelee -alpha2delta2-a et alpha2delta2-b

Publications (1)

Publication Number Publication Date
CA2526887A1 true CA2526887A1 (fr) 2004-11-04

Family

ID=33310829

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002526887A Abandoned CA2526887A1 (fr) 2003-04-18 2004-04-16 Variants d'epissage d'une sous-unite humaine alpha2delta-2 des canaux calciques dependants d'un potentiel d'action appelee -alpha2delta2-a et alpha2delta2-b

Country Status (3)

Country Link
EP (1) EP1618180A2 (fr)
CA (1) CA2526887A1 (fr)
WO (1) WO2004094604A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018274569B2 (en) * 2017-05-26 2022-06-30 Novassay Sa Voltage-Gated Calcium Channel auxilliary subunit alpha 2 delta and uses thereof

Also Published As

Publication number Publication date
EP1618180A2 (fr) 2006-01-25
WO2004094604A9 (fr) 2010-01-28
WO2004094604A2 (fr) 2004-11-04

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued