CA2522261A1 - Identification and monitoring of systematic lupus erythematosus - Google Patents

Identification and monitoring of systematic lupus erythematosus Download PDF

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Publication number
CA2522261A1
CA2522261A1 CA002522261A CA2522261A CA2522261A1 CA 2522261 A1 CA2522261 A1 CA 2522261A1 CA 002522261 A CA002522261 A CA 002522261A CA 2522261 A CA2522261 A CA 2522261A CA 2522261 A1 CA2522261 A1 CA 2522261A1
Authority
CA
Canada
Prior art keywords
individual
complement
lupus erythematosus
systemic lupus
platelets obtained
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002522261A
Other languages
English (en)
French (fr)
Inventor
Joseph M. Ahearn
Susan M. Manzi
Jeannine Navratil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pittsburgh
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2522261A1 publication Critical patent/CA2522261A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104—Lupus erythematosus [SLE]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/821—Chemistry: analytical and immunological testing involving complement factors or complement systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Dc Digital Transmission (AREA)
  • Small-Scale Networks (AREA)
  • Testing Of Coins (AREA)
CA002522261A 2003-04-16 2004-04-16 Identification and monitoring of systematic lupus erythematosus Abandoned CA2522261A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46344703P 2003-04-16 2003-04-16
US60/463,447 2003-04-16
PCT/US2004/011982 WO2004093647A2 (en) 2003-04-16 2004-04-16 Identification and monitoring of systematic lupus erythematosus

Publications (1)

Publication Number Publication Date
CA2522261A1 true CA2522261A1 (en) 2004-11-04

Family

ID=33310779

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002522261A Abandoned CA2522261A1 (en) 2003-04-16 2004-04-16 Identification and monitoring of systematic lupus erythematosus

Country Status (7)

Country Link
US (3) US7588905B2 (enExample)
EP (1) EP1618379B1 (enExample)
JP (1) JP4550051B2 (enExample)
AT (1) ATE552501T1 (enExample)
AU (1) AU2004232007B2 (enExample)
CA (1) CA2522261A1 (enExample)
WO (1) WO2004093647A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060015646A (ko) 2003-06-13 2006-02-17 유니버시티 오브 피츠버그 면역, 혈액 및 염증성 질환의 모니터링 방법
US20080131914A1 (en) * 2005-09-14 2008-06-05 Ahearn Joseph M Assessing risk of cerebrovascular thrombosis by measuring c4d
US8062852B2 (en) * 2007-10-01 2011-11-22 The Children's Hospital And Regional Medical Center Detection and treatment of autoimmune disorders
AU2009305575A1 (en) * 2008-10-16 2010-04-22 Cypress Bioscience, Inc. Method for diagnosis and monitoring of disease activity and response to treatment in systemic lupus erythematosus (SLE) and other autoimmune diseases
JP5625155B2 (ja) * 2010-07-30 2014-11-19 国立大学法人 東京大学 ホスファチジルセリン特異的ホスホリパーゼａ１測定による全身性エリテマトーデスの検査方法および検査薬
US10132813B2 (en) 2011-02-11 2018-11-20 Exagen Diagnostics, Inc. Methods for diagnosing systemic lupus erythematosus
US9863946B2 (en) 2013-02-08 2018-01-09 Allegheny-Singer Research Institute Cell-bound complement activation products as diagnostic biomarkers for pre-lupus
RU2019103573A (ru) 2013-02-08 2019-03-15 Аллегени-Сингер Рисерч Инститьют Клеточно-связанные продукты активации комплемента в качестве диагностических биомаркеров волчанки в доклинической стадии
CN105229470B (zh) 2013-03-15 2018-11-27 艾克斯肯诊断股份有限公司 用于治疗和诊断系统性红斑狼疮的方法
WO2014199364A1 (en) 2013-06-13 2014-12-18 Bnai Zion Medical Center Semaphorin 3a for treatment and prognosis of systemic lupus erythematosus
EP3329278A4 (en) 2015-07-31 2019-01-16 Allegheny-Singer Research Institute CELL-ASSOCIATED COMPLEMENT ACTIVATION PRODUCTS AS COMPARATIVE DIAGNOSTICS FOR ANTIBODY-BASED MEDICAMENTS
EP3465210B1 (en) 2016-05-24 2022-11-02 Allegheny-Singer Research Institute Methods and systems using c4 gene copy number and cell-bound complement activation products for identification of lupus and pre-lupus
EP4264282B1 (en) * 2020-12-21 2026-06-03 Sedicidodici Srl Method for evaluating blood parameters

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994010571A1 (en) 1992-10-30 1994-05-11 T Cell Sciences, Inc. Measurement of total molecule in a sample and methods based thereon
WO1999045094A1 (en) * 1998-03-02 1999-09-10 Compucyte Corp. Selective cell analysis
ATE479707T1 (de) * 2001-09-10 2010-09-15 Univ Pittsburgh Diagnose und aufzeichnung von systemischem lupus erythematosus und von skleroderm
KR20060015646A (ko) * 2003-06-13 2006-02-17 유니버시티 오브 피츠버그 면역, 혈액 및 염증성 질환의 모니터링 방법
WO2005108988A2 (en) * 2004-04-09 2005-11-17 University Of Pittsburgh Real time method of detecting acute inflammatory conditions
EP2214014A1 (en) * 2004-05-11 2010-08-04 The University of Pittsburgh Monitoring immunologic, hematologic and inflammatory diseases
US7679298B2 (en) * 2006-08-17 2010-03-16 General Electric Company Locomotive wheel speed control

Also Published As

Publication number Publication date
EP1618379A2 (en) 2006-01-25
JP4550051B2 (ja) 2010-09-22
AU2004232007B2 (en) 2009-10-22
US20090299948A1 (en) 2009-12-03
WO2004093647A2 (en) 2004-11-04
ATE552501T1 (de) 2012-04-15
US20120122241A1 (en) 2012-05-17
EP1618379B1 (en) 2012-04-04
US7588905B2 (en) 2009-09-15
AU2004232007A1 (en) 2004-11-04
US8126654B2 (en) 2012-02-28
US20070178536A1 (en) 2007-08-02
EP1618379A4 (en) 2008-05-07
JP2006524342A (ja) 2006-10-26
WO2004093647A3 (en) 2005-03-10

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20130506