CA2516450A1 - Method to treat chronic heart failure and/or elevated cholesterol levels - Google Patents

Method to treat chronic heart failure and/or elevated cholesterol levels Download PDF

Info

Publication number
CA2516450A1
CA2516450A1 CA002516450A CA2516450A CA2516450A1 CA 2516450 A1 CA2516450 A1 CA 2516450A1 CA 002516450 A CA002516450 A CA 002516450A CA 2516450 A CA2516450 A CA 2516450A CA 2516450 A1 CA2516450 A1 CA 2516450A1
Authority
CA
Canada
Prior art keywords
acid
tetraiodothyropropionic
triiodothyropropionic
administered
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002516450A
Other languages
English (en)
French (fr)
Inventor
Eugene Morkin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arizona's Public Universities
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2516450A1 publication Critical patent/CA2516450A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CA002516450A 2003-02-18 2003-10-20 Method to treat chronic heart failure and/or elevated cholesterol levels Abandoned CA2516450A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/368,755 US6716877B2 (en) 2001-01-31 2003-02-18 Method to treat chronic heart failure and/or elevated cholesterol levels
US10/368,755 2003-02-18
PCT/US2003/033333 WO2004073694A1 (en) 2003-02-18 2003-10-20 Method to treat chronic heart failure and/or elevated cholesterol levels

Publications (1)

Publication Number Publication Date
CA2516450A1 true CA2516450A1 (en) 2004-09-02

Family

ID=32907645

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002516450A Abandoned CA2516450A1 (en) 2003-02-18 2003-10-20 Method to treat chronic heart failure and/or elevated cholesterol levels

Country Status (7)

Country Link
US (1) US6716877B2 (enExample)
EP (1) EP1594480A4 (enExample)
JP (1) JP2006514665A (enExample)
AU (1) AU2003286546B2 (enExample)
CA (1) CA2516450A1 (enExample)
MX (1) MXPA05008596A (enExample)
WO (1) WO2004073694A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI107018B (fi) * 2000-04-06 2001-05-31 Ipsat Therapies Oy Dermatologinen käyttö ja valmiste
US7504435B2 (en) * 2001-01-31 2009-03-17 The Arizona Board Of Regents On Behalf Of The University Of Arizona Method for stimulating weight loss and/or for lowering triglycerides in patients
WO2006128058A2 (en) 2005-05-26 2006-11-30 Metabasis Therapeutics, Inc. Thyromimetics for the treatment of fatty liver diseases
WO2005051298A2 (en) * 2003-11-19 2005-06-09 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
WO2006128056A2 (en) * 2005-05-26 2006-11-30 Metabasis Therapeutics, Inc. Novel phosphinic acid-containing thyromimetics
JPWO2009028608A1 (ja) * 2007-08-31 2010-12-02 三菱瓦斯化学株式会社 オルト位がヨウ素置換されたフェノール誘導体の製造方法
US20090131380A1 (en) * 2007-11-16 2009-05-21 Pekka Heino Novel pharmaceutical composition for topical treatment of skin psoriasis and the treatment method thereof
PT3104939T (pt) * 2014-02-10 2024-07-17 Fred Hutchinson Cancer Center Tratamento de ataque cardíaco e lesão isquémica com iodeto de sódio
AU2017363206A1 (en) 2016-11-21 2019-06-13 Viking Therapeutics, Inc. Method of treating glycogen storage disease
EP3634426A4 (en) 2017-06-05 2021-04-07 Viking Therapeutics, Inc. COMPOSITIONS FOR TREATMENT OF FIBROSE
US11458094B2 (en) * 2018-01-31 2022-10-04 Regents Of The University Of Minnesota Compositions and methods for treating pulmonary edema or lung inflammation
MX2020009843A (es) 2018-03-22 2020-12-11 Viking Therapeutics Inc Formas cristalinas y metodos de produccion de formas cristalinas de un compuesto.
WO2020117962A1 (en) 2018-12-05 2020-06-11 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis and inflammation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3109023A (en) 1958-06-10 1963-10-29 Hooker Chemical Corp 2, 3, 6-trichloro-5-nitrobenzoic acid and salts thereof
US5158978A (en) * 1990-02-05 1992-10-27 British Technology Group (U.S.A.) Thyroid hormone treatment of acute cardiovascular compromise
US5284971A (en) 1992-07-16 1994-02-08 Syntex (U.S.A.) Inc. 4-(3-cyclohexyl-4-hydroxy or-methoxy phenylsulfonyl) 3,5 dibromo phenyl acetic thyromimetic cholesterol-lowering agents
US6221911B1 (en) * 1995-06-07 2001-04-24 Karo Bio Ab Uses for thyroid hormone compounds or thyroid hormone-like compounds
US5883294A (en) 1997-06-18 1999-03-16 The Regeants Of The University Of California Selective thyroid hormone analogs
US6534676B2 (en) * 2001-01-31 2003-03-18 The Arizona Board Of Regents On Behalf Of The University Of Arizona Method to treat chronic heart failure and/or elevated cholesterol levels using 3,5-diiodothyropropionic acid and method to prepare same

Also Published As

Publication number Publication date
MXPA05008596A (es) 2006-02-28
EP1594480A4 (en) 2007-08-29
WO2004073694A1 (en) 2004-09-02
US20030147815A1 (en) 2003-08-07
US6716877B2 (en) 2004-04-06
AU2003286546A1 (en) 2004-09-09
AU2003286546B2 (en) 2009-06-11
EP1594480A1 (en) 2005-11-16
JP2006514665A (ja) 2006-05-11

Similar Documents

Publication Publication Date Title
CA2436421C (en) Method to treat chronic heart failure and/or elevated cholesterol levels using 3,5-diiodothyropropionic acid and method to prepare same
AU2002243801A1 (en) Method to treat chronic heart failure and/or elevated cholesterol levels using 3,5-diiodothyropropionic acid and method to prepare same
US6045827A (en) Treatment of equine laminitis
AU2003286546B2 (en) Method to treat chronic heart failure and/or elevated cholesterol levels
KR100267442B1 (ko) 아세틸살리실산을 함유하는 혈전증 치료용 및 암 예방용 경피적 투여시스템
US8071125B2 (en) Transdermal patch containing isosorbide dinitrate and bisoprolol
Yau et al. Vitamin E for coronary bypass operations: a prospective, double-blind, randomized trial
CN118001256A (zh) 氟比洛芬的外用制剂及其制备方法
US20050159490A1 (en) Method to treat chronic heart failure and/or elevated cholesterol levels
US20050266060A1 (en) Transdermal delivery system for treatment of cognitive disorders
AU2001287706B2 (en) Treatment of burns
SK75495A3 (en) Transdermal administration system containing acetylsalicylic acid for antithrombotic therapy and the prophylaxis of cancer
JP2003246737A (ja) 皮膚外用組成物
AU2001287706A1 (en) Treatment of burns
JPH0611716B2 (ja) 経皮吸収促進剤
JPH0193542A (ja) 医薬外用製剤
CN114469878A (zh) 一种普罗布考干乳剂组合物及其制备方法和应用
JPH06247846A (ja) 塩酸リトドリンの経皮吸収製剤用組成物
IE83245B1 (en) Treatment of burns
JP2004051522A (ja) 血液透析による皮膚疾患及び痒みの治療用外用剤

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued