CA2513201C - Capsule for receiving an active substance which is administrable by inhalation - Google Patents
Capsule for receiving an active substance which is administrable by inhalation Download PDFInfo
- Publication number
- CA2513201C CA2513201C CA2513201A CA2513201A CA2513201C CA 2513201 C CA2513201 C CA 2513201C CA 2513201 A CA2513201 A CA 2513201A CA 2513201 A CA2513201 A CA 2513201A CA 2513201 C CA2513201 C CA 2513201C
- Authority
- CA
- Canada
- Prior art keywords
- capsule
- chamber
- longitudinal axis
- inhaler
- capsules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002775 capsule Substances 0.000 title claims abstract description 265
- 239000013543 active substance Substances 0.000 title abstract description 8
- 239000000843 powder Substances 0.000 claims abstract description 21
- 238000007789 sealing Methods 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 5
- 238000005520 cutting process Methods 0.000 description 25
- 238000000034 method Methods 0.000 description 9
- 238000010276 construction Methods 0.000 description 4
- 239000000443 aerosol Substances 0.000 description 3
- 230000000295 complement effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000012634 fragment Substances 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 239000008194 pharmaceutical composition Substances 0.000 description 3
- 239000001828 Gelatine Substances 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 238000005304 joining Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 238000002604 ultrasonography Methods 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 230000008093 supporting effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0035—Piercing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10300984.1 | 2003-01-14 | ||
| DE2003100984 DE10300984A1 (de) | 2003-01-14 | 2003-01-14 | Kapsel zur Aufnahme eines inhalativ applizierbaren Wirkstoffs |
| PCT/EP2003/014694 WO2004062640A2 (de) | 2003-01-14 | 2003-12-20 | Kapsel zur aufnahme eines inhalativ applizierbaren wirkstoffs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2513201A1 CA2513201A1 (en) | 2004-07-29 |
| CA2513201C true CA2513201C (en) | 2012-10-02 |
Family
ID=32519907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2513201A Expired - Lifetime CA2513201C (en) | 2003-01-14 | 2003-12-20 | Capsule for receiving an active substance which is administrable by inhalation |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1587564A2 (de) |
| JP (1) | JP2006517421A (de) |
| AU (1) | AU2003300220A1 (de) |
| CA (1) | CA2513201C (de) |
| DE (1) | DE10300984A1 (de) |
| WO (1) | WO2004062640A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007036411A1 (de) | 2007-07-20 | 2009-02-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| TR200803525A2 (tr) * | 2008-05-16 | 2009-12-21 | Bi̇lgi̇ç Mahmut | Toz ilaç soluma cihazı. |
| JP5415341B2 (ja) * | 2010-03-31 | 2014-02-12 | 株式会社吉野工業所 | 粉体吸入デバイス |
| US10220165B2 (en) * | 2011-05-27 | 2019-03-05 | Boehringer Ingelheim International Gmbh | Inhalator and capsule for an inhalator |
| PT107627B (pt) * | 2014-04-29 | 2017-03-08 | Hovione Farmaciência S A | Inalador de cápsulas com dobradiça |
| EP3167868A1 (de) * | 2015-11-16 | 2017-05-17 | Capsugel Belgium NV | Manipulationssichere darreichungsform |
| EP3167867A1 (de) * | 2015-11-16 | 2017-05-17 | Capsugel Belgium NV | Manipulationssichere darreichungsform |
| CN111012671B (zh) * | 2019-11-25 | 2022-07-05 | 上海强德食品科技有限公司 | 一种微胶囊的物理制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE395611B (sv) * | 1975-12-12 | 1977-08-22 | Draco Ab | Aerosolinhalationsanordning avsedd for inhalering genom ett inhaleringsmunstycke av farmakologiskt aktiva substanser |
| GB8325529D0 (en) * | 1983-09-23 | 1983-10-26 | Lilly Industries Ltd | Medicinal forms |
| DE3345722A1 (de) * | 1983-12-17 | 1985-06-27 | Boehringer Ingelheim KG, 6507 Ingelheim | Inhalator |
| DE3927170A1 (de) * | 1989-08-17 | 1991-02-21 | Boehringer Ingelheim Kg | Inhalator |
| AU650953B2 (en) * | 1991-03-21 | 1994-07-07 | Novartis Ag | Inhaler |
| DE4318455A1 (de) * | 1993-06-03 | 1994-12-08 | Boehringer Ingelheim Kg | Kapselhalterung |
| JP3372105B2 (ja) * | 1994-05-26 | 2003-01-27 | 株式会社日立ユニシアオートモティブ | 吸入式投薬器 |
| DE19835346A1 (de) * | 1998-08-05 | 2000-02-10 | Boehringer Ingelheim Pharma | Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren |
| GB2357488A (en) * | 1999-11-17 | 2001-06-27 | Aquasol Ltd | Capsules by injection moulding |
-
2003
- 2003-01-14 DE DE2003100984 patent/DE10300984A1/de not_active Withdrawn
- 2003-12-20 JP JP2004566013A patent/JP2006517421A/ja active Pending
- 2003-12-20 EP EP03799497A patent/EP1587564A2/de not_active Ceased
- 2003-12-20 CA CA2513201A patent/CA2513201C/en not_active Expired - Lifetime
- 2003-12-20 AU AU2003300220A patent/AU2003300220A1/en not_active Abandoned
- 2003-12-20 WO PCT/EP2003/014694 patent/WO2004062640A2/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA2513201A1 (en) | 2004-07-29 |
| WO2004062640A2 (de) | 2004-07-29 |
| DE10300984A1 (de) | 2004-07-22 |
| WO2004062640A3 (de) | 2004-10-21 |
| JP2006517421A (ja) | 2006-07-27 |
| AU2003300220A8 (en) | 2004-08-10 |
| AU2003300220A1 (en) | 2004-08-10 |
| EP1587564A2 (de) | 2005-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20231220 |