CA2513077A1 - Use of l-dopa, derivatives thereof and medicaments comprising said compounds for the prophylaxis of psychotic diseases - Google Patents
Use of l-dopa, derivatives thereof and medicaments comprising said compounds for the prophylaxis of psychotic diseases Download PDFInfo
- Publication number
- CA2513077A1 CA2513077A1 CA002513077A CA2513077A CA2513077A1 CA 2513077 A1 CA2513077 A1 CA 2513077A1 CA 002513077 A CA002513077 A CA 002513077A CA 2513077 A CA2513077 A CA 2513077A CA 2513077 A1 CA2513077 A1 CA 2513077A1
- Authority
- CA
- Canada
- Prior art keywords
- dopa
- derivatives
- physiologically compatible
- compatible salts
- well
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 title claims abstract description 36
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 title claims abstract description 35
- 208000028017 Psychotic disease Diseases 0.000 title claims abstract description 18
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- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 description 1
- 229940113147 shellac Drugs 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 235000010356 sorbitol Nutrition 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 235000010215 titanium dioxide Nutrition 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
- A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10261808.9 | 2002-12-19 | ||
| DE10261808A DE10261808A1 (de) | 2002-12-19 | 2002-12-19 | Verwendung von L-DOPA, seiner Derivate und diese Verbindungen enthaltender Arzneimittel zur Prophylaxe psychotischer Erkrankungen |
| PCT/DE2003/004204 WO2004056306A2 (de) | 2002-12-19 | 2003-12-18 | Verwendung von l-dopa, seiner derivate und diese verbindungen enthaltender arzneimittel zur prophylaxe psychotischer erkrankungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2513077A1 true CA2513077A1 (en) | 2004-07-08 |
Family
ID=32478131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002513077A Abandoned CA2513077A1 (en) | 2002-12-19 | 2003-12-18 | Use of l-dopa, derivatives thereof and medicaments comprising said compounds for the prophylaxis of psychotic diseases |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1615631A2 (es) |
| JP (1) | JP2006511558A (es) |
| CN (1) | CN1756542A (es) |
| AU (1) | AU2003294664A1 (es) |
| CA (1) | CA2513077A1 (es) |
| DE (1) | DE10261808A1 (es) |
| EA (1) | EA200500957A1 (es) |
| MX (1) | MXPA05006409A (es) |
| PL (1) | PL377524A1 (es) |
| WO (1) | WO2004056306A2 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8735382B2 (en) | 2004-07-12 | 2014-05-27 | Dizlin Medical Design Ab | Infusion and injection solution of levodopa |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1991522T3 (pl) * | 2006-02-17 | 2017-07-31 | Ratiopharm Gmbh | Deuterowane pochodne katecholaminy i leki zawierające te związki |
| CN105078952A (zh) * | 2015-08-10 | 2015-11-25 | 中国康复研究中心 | 一种左旋多巴制剂及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52102431A (en) * | 1976-02-25 | 1977-08-27 | Kyowa Hakko Kogyo Co Ltd | Remedies for mental disorder |
| IE47082B1 (en) * | 1977-07-01 | 1983-12-14 | Merrell Toraude & Co | -acetylenic amino acids |
| US5149786A (en) * | 1989-10-12 | 1992-09-22 | Chiron Corporation | Dopamine releasing protein and antibody |
-
2002
- 2002-12-19 DE DE10261808A patent/DE10261808A1/de not_active Ceased
-
2003
- 2003-12-18 PL PL377524A patent/PL377524A1/pl not_active Application Discontinuation
- 2003-12-18 WO PCT/DE2003/004204 patent/WO2004056306A2/de not_active Application Discontinuation
- 2003-12-18 JP JP2004561055A patent/JP2006511558A/ja active Pending
- 2003-12-18 AU AU2003294664A patent/AU2003294664A1/en not_active Abandoned
- 2003-12-18 EP EP03785594A patent/EP1615631A2/de not_active Withdrawn
- 2003-12-18 CA CA002513077A patent/CA2513077A1/en not_active Abandoned
- 2003-12-18 CN CNA2003801066148A patent/CN1756542A/zh active Pending
- 2003-12-18 MX MXPA05006409A patent/MXPA05006409A/es unknown
- 2003-12-18 EA EA200500957A patent/EA200500957A1/ru unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8735382B2 (en) | 2004-07-12 | 2014-05-27 | Dizlin Medical Design Ab | Infusion and injection solution of levodopa |
| US9248113B2 (en) | 2004-07-12 | 2016-02-02 | Dizlin Medical Design Ab | Infusion and injection solution of Levodopa |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006511558A (ja) | 2006-04-06 |
| EA200500957A1 (ru) | 2006-02-24 |
| EP1615631A2 (de) | 2006-01-18 |
| WO2004056306A3 (de) | 2004-11-11 |
| CN1756542A (zh) | 2006-04-05 |
| PL377524A1 (pl) | 2006-02-06 |
| WO2004056306A2 (de) | 2004-07-08 |
| DE10261808A1 (de) | 2004-07-08 |
| MXPA05006409A (es) | 2006-05-31 |
| AU2003294664A1 (en) | 2004-07-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |