CA2506128A1 - Anti-activated ras antibodies - Google Patents
Anti-activated ras antibodies Download PDFInfo
- Publication number
- CA2506128A1 CA2506128A1 CA002506128A CA2506128A CA2506128A1 CA 2506128 A1 CA2506128 A1 CA 2506128A1 CA 002506128 A CA002506128 A CA 002506128A CA 2506128 A CA2506128 A CA 2506128A CA 2506128 A1 CA2506128 A1 CA 2506128A1
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- Prior art keywords
- seq
- antibody
- scfv
- ras
- variable domain
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0226731.8 | 2002-11-15 | ||
| GB0226727.6 | 2002-11-15 | ||
| GB0226723.5 | 2002-11-15 | ||
| GBGB0226727.6A GB0226727D0 (en) | 2002-11-15 | 2002-11-15 | Intrabodies |
| GB0226723A GB0226723D0 (en) | 2002-11-15 | 2002-11-15 | Antibodies for in vitro use |
| GBGB0226729.2A GB0226729D0 (en) | 2002-11-15 | 2002-11-15 | Intracellular antibodies |
| GB0226728.4 | 2002-11-15 | ||
| GB0226728A GB0226728D0 (en) | 2002-11-15 | 2002-11-15 | Anti-activated RAS antibodies |
| GB0226731A GB0226731D0 (en) | 2002-11-15 | 2002-11-15 | Method for generating immunoglobulin genes |
| GB0226729.2 | 2002-11-15 | ||
| GB0316680A GB0316680D0 (en) | 2003-07-16 | 2003-07-16 | Anti-activated RAS antibodies |
| GB0316680.8 | 2003-07-16 | ||
| PCT/GB2003/004953 WO2004046188A2 (en) | 2002-11-15 | 2003-11-14 | Anti-activated ras antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2506128A1 true CA2506128A1 (en) | 2004-06-03 |
Family
ID=32330172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002506128A Abandoned CA2506128A1 (en) | 2002-11-15 | 2003-11-14 | Anti-activated ras antibodies |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050288492A1 (enExample) |
| EP (1) | EP1565495A2 (enExample) |
| JP (1) | JP2006521088A (enExample) |
| AU (1) | AU2003282247A1 (enExample) |
| CA (1) | CA2506128A1 (enExample) |
| WO (1) | WO2004046188A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2558338T3 (es) | 2005-03-25 | 2016-02-03 | National Research Council Of Canada | Método para aislamiento de polipéptidos solubles |
| EP1867661A1 (en) * | 2006-06-12 | 2007-12-19 | Diatos | Compositions and methods for delivering anti-activated ras antibodies into cells |
| US8532164B2 (en) | 2008-03-12 | 2013-09-10 | Panasonic Corporation | Wireless communication apparatus, wireless communication system, and wireless communication method |
| JP2012523244A (ja) * | 2009-04-14 | 2012-10-04 | トロジャン テクノロジーズ リミテッド | 治療用アンテナペディア−抗体分子およびその使用法 |
| GB201103631D0 (en) * | 2011-03-03 | 2011-04-13 | Univ Leeds | Identification of candidate therapeutics |
| CA2911514A1 (en) | 2013-05-06 | 2014-11-13 | Scholar Rock, Inc. | Compositions and methods for growth factor modulation |
| KR101602870B1 (ko) | 2014-07-22 | 2016-03-21 | 아주대학교산학협력단 | 완전한 이뮤노글로불린 형태의 항체를 세포막을 투과하여 세포질에 위치시키는 방법 및 그의 이용 |
| KR101602876B1 (ko) | 2014-07-22 | 2016-03-11 | 아주대학교산학협력단 | 완전한 이뮤노글로불린 형태의 세포질 침투능을 갖는 항체를 이용하여 세포내 활성화된 ras를 억제하는 방법 및 그의 이용 |
| WO2016013871A1 (ko) * | 2014-07-22 | 2016-01-28 | 아주대학교산학협력단 | 완전한 이뮤노글로불린 형태의 세포질 침투능을 갖는 항체를 이용하여 세포내 활성화된 ras를 억제하는 방법 및 그의 이용 |
| IL278574B2 (en) | 2014-11-12 | 2024-11-01 | Seagen Inc | Glycan-interacting compounds and methods of use |
| US9879087B2 (en) | 2014-11-12 | 2018-01-30 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
| WO2017083582A1 (en) | 2015-11-12 | 2017-05-18 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
| MX2018014554A (es) | 2016-05-27 | 2019-09-09 | Orum Therapeutics Inc | Anticuerpo penetrante de citosol y uso del mismo. |
| WO2018094143A1 (en) | 2016-11-17 | 2018-05-24 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
| KR20240044544A (ko) | 2017-03-03 | 2024-04-04 | 씨젠 인크. | 글리칸-상호작용 화합물 및 사용 방법 |
| US11965004B2 (en) * | 2017-07-10 | 2024-04-23 | Sri International | Molecular guide system peptides and uses thereof |
| KR20190143826A (ko) | 2018-06-21 | 2019-12-31 | 오름테라퓨틱 주식회사 | 세포/조직 특이적 세포 침투 항체 |
| GB202006974D0 (en) * | 2020-05-12 | 2020-06-24 | Univ Oxford Innovation Ltd | Chimaeric proteins and therapeutic agents |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003219277A1 (en) * | 2002-03-14 | 2003-09-29 | Medical Research Council | Intracellular antibodies |
-
2003
- 2003-11-14 JP JP2004570301A patent/JP2006521088A/ja not_active Withdrawn
- 2003-11-14 EP EP03773865A patent/EP1565495A2/en not_active Withdrawn
- 2003-11-14 AU AU2003282247A patent/AU2003282247A1/en not_active Abandoned
- 2003-11-14 WO PCT/GB2003/004953 patent/WO2004046188A2/en not_active Ceased
- 2003-11-14 CA CA002506128A patent/CA2506128A1/en not_active Abandoned
-
2005
- 2005-05-12 US US11/127,903 patent/US20050288492A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1565495A2 (en) | 2005-08-24 |
| AU2003282247A1 (en) | 2004-06-15 |
| WO2004046188A2 (en) | 2004-06-03 |
| US20050288492A1 (en) | 2005-12-29 |
| WO2004046188A3 (en) | 2004-09-16 |
| JP2006521088A (ja) | 2006-09-21 |
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