CA2503492A1 - Dispositifs medicaux implantables utilisant du zinc - Google Patents

Dispositifs medicaux implantables utilisant du zinc Download PDF

Info

Publication number
CA2503492A1
CA2503492A1 CA002503492A CA2503492A CA2503492A1 CA 2503492 A1 CA2503492 A1 CA 2503492A1 CA 002503492 A CA002503492 A CA 002503492A CA 2503492 A CA2503492 A CA 2503492A CA 2503492 A1 CA2503492 A1 CA 2503492A1
Authority
CA
Canada
Prior art keywords
zinc
containing component
tissue
implantable medical
coupling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002503492A
Other languages
English (en)
Inventor
Pamela Cifra
Michael D. Dake
Christopher Elkins
Jacob M. Waugh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Revance Therapeuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2503492A1 publication Critical patent/CA2503492A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/315—Zinc compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/082—Inorganic materials
    • A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des dispositifs médicaux implantables utilisant du zinc ainsi que des méthodes associées permettant de produire un ou plusieurs effets bénéfiques dans un tissu. Dans un mode de réalisation, au moins un composé contenant du zinc est couplé à un stent par l'intermédiaire d'un ou plusieurs chélateurs de zinc de sorte à augmenter la résistance du stent à la formation de plaques et à la resténose intra-stent. La production d'élastine peut également être renforcée au moyen de dispositifs couplés à du zinc. Une production d'élastine accrue peut servir, par exemple, à traiter un vaisseau sanguin dans un emplacement situé au niveau ou au voisinage d'un anévrisme. Dans certains modes de réalisation, la production d'élastine et la résistance aux plaques sont toutes deux augmentées. Par exemple, du zinc peut être appliqué par l'intermédiaire d'un gel ou d'une autre substance support sur un greffon veineux en vue d'augmenter la production d'élastine et la résistance à la formation de plaques. Les dispositifs implantables couplés au zinc permettent d'obtenir des résultats améliorés dans des opérations médicales et chirurgicales faisant appel à des dispositifs médicaux, ce qui réduit la nécessité de répéter ces opérations.
CA002503492A 2002-10-25 2003-10-22 Dispositifs medicaux implantables utilisant du zinc Abandoned CA2503492A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42127802P 2002-10-25 2002-10-25
US42133602P 2002-10-25 2002-10-25
US60/421,278 2002-10-25
US60/421,336 2002-10-25
PCT/US2003/033752 WO2004037120A2 (fr) 2002-10-25 2003-10-22 Dispositifs medicaux implantables utilisant du zinc

Publications (1)

Publication Number Publication Date
CA2503492A1 true CA2503492A1 (fr) 2004-05-06

Family

ID=39273388

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002503492A Abandoned CA2503492A1 (fr) 2002-10-25 2003-10-22 Dispositifs medicaux implantables utilisant du zinc

Country Status (5)

Country Link
EP (1) EP1560543A2 (fr)
JP (1) JP2006503657A (fr)
AU (1) AU2003286660A1 (fr)
CA (1) CA2503492A1 (fr)
WO (1) WO2004037120A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109589456B (zh) * 2017-09-30 2024-03-19 元心科技(深圳)有限公司 植入式器械

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099562A (en) * 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US6776792B1 (en) * 1997-04-24 2004-08-17 Advanced Cardiovascular Systems Inc. Coated endovascular stent
FR2777193B1 (fr) * 1998-04-14 2001-06-08 Coletica Particule a groupement hydroxamique chelatante d'ions metalliques et leur utilisation en cosmetique ou en pharmacie
IT1303735B1 (it) * 1998-11-11 2001-02-23 Falorni Italia Farmaceutici S Acidi ialuronici reticolati e loro usi medici.
US7182953B2 (en) * 1999-12-15 2007-02-27 Celgene Corporation Methods and compositions for the prevention and treatment of atherosclerosis restenosis and related disorders
US6716444B1 (en) * 2000-09-28 2004-04-06 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same

Also Published As

Publication number Publication date
WO2004037120A2 (fr) 2004-05-06
WO2004037120A3 (fr) 2005-04-07
EP1560543A2 (fr) 2005-08-10
AU2003286660A1 (en) 2004-05-13
JP2006503657A (ja) 2006-02-02

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Legal Events

Date Code Title Description
FZDE Discontinued