CA2490051A1 - Nouvelles sequences gdf-9 et gdf-9b (bmp-15) destinees a modifier la fonction ovarienne et la vitesse d'ovulation chez des mammiferes - Google Patents
Nouvelles sequences gdf-9 et gdf-9b (bmp-15) destinees a modifier la fonction ovarienne et la vitesse d'ovulation chez des mammiferes Download PDFInfo
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- CA2490051A1 CA2490051A1 CA002490051A CA2490051A CA2490051A1 CA 2490051 A1 CA2490051 A1 CA 2490051A1 CA 002490051 A CA002490051 A CA 002490051A CA 2490051 A CA2490051 A CA 2490051A CA 2490051 A1 CA2490051 A1 CA 2490051A1
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- 230000002103 transcriptional effect Effects 0.000 description 1
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- 230000001052 transient effect Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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- IBIDRSSEHFLGSD-UHFFFAOYSA-N valinyl-arginine Natural products CC(C)C(N)C(=O)NC(C(O)=O)CCCN=C(N)N IBIDRSSEHFLGSD-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Reproductive Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Toxicology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Gynecology & Obstetrics (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne des compositions et des procédés permettant de moduler la vitesse d'ovulation et, par là même, la fertilité chez des mammifères femelles, et notamment chez la femme. Cette invention concerne également de nouvelles mutations dans les gènes GDF-9 et GDF-9B, lesquels sont associés à des modifications de la fertilité.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ519330 | 2002-05-30 | ||
| NZ51933002A NZ519330A (en) | 2002-05-30 | 2002-05-30 | New sequences for altering mammalian ovarian function and ovulation rate |
| PCT/NZ2003/000109 WO2003102199A1 (fr) | 2002-05-30 | 2003-05-30 | Nouvelles sequences gdf-9 et gdf-9b (bmp-15) destinees a modifier la fonction ovarienne et la vitesse d'ovulation chez des mammiferes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2490051A1 true CA2490051A1 (fr) | 2003-12-11 |
Family
ID=29707820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002490051A Abandoned CA2490051A1 (fr) | 2002-05-30 | 2003-05-30 | Nouvelles sequences gdf-9 et gdf-9b (bmp-15) destinees a modifier la fonction ovarienne et la vitesse d'ovulation chez des mammiferes |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1551973A4 (fr) |
| JP (1) | JP2006510345A (fr) |
| AU (1) | AU2003235525B2 (fr) |
| BR (1) | BR0311465A (fr) |
| CA (1) | CA2490051A1 (fr) |
| NZ (1) | NZ519330A (fr) |
| WO (1) | WO2003102199A1 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008521892A (ja) * | 2004-12-02 | 2008-06-26 | アグリサーチ・リミテッド | 排卵の調節 |
| WO2006059913A1 (fr) * | 2004-12-02 | 2006-06-08 | Agresearch Limited | Modulation de l'ovulation |
| WO2006130022A1 (fr) * | 2005-05-30 | 2006-12-07 | Agresearch Limited | Modulation de l'ovulation au moyen d'agonistes et d'antagonistes de bmprii |
| US20100203502A1 (en) * | 2005-09-13 | 2010-08-12 | Moron Francisco J | Method for the in Vitro Detection of a Predisposition to the Development of Alterations in Ovarian Function |
| BRPI0706173C1 (pt) * | 2007-11-23 | 2011-02-22 | Brasil Pesquisa Agropec | metodo para identificação massal de animais com aumento na prolificidade |
| ES2338960B1 (es) * | 2007-11-23 | 2011-04-19 | Carnes Oviaragon S.C.L. | Procedimiento de mejora de la productividad en ganado ovino. |
| WO2014018404A1 (fr) * | 2012-07-21 | 2014-01-30 | Baylor College Of Medicine | Hétérodimères gdf9/bmp15 pour augmenter la fertilité |
| CN104774836A (zh) * | 2015-04-15 | 2015-07-15 | 兰州大学 | 一种提高绵羊产羔数多基因聚合早期选种的方法 |
| CN110914686A (zh) * | 2017-02-01 | 2020-03-24 | 新南创新私人有限公司 | 配子分泌的生长因子 |
| CN112601756A (zh) | 2018-05-09 | 2021-04-02 | 莫拿什大学 | 用于增强生育力的剂和方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6030617A (en) * | 1993-01-12 | 2000-02-29 | The Johns Hopkins University School Of Medicine | Use of growth differentiation factor-9 (GDF-9) to inhibit oocyte maturation |
| WO2000066620A2 (fr) * | 1999-04-30 | 2000-11-09 | Curis, Inc. | Augmentation de fertilite induite par des morphogenes |
| NZ500844A (en) * | 2000-05-05 | 2003-06-30 | Agres Ltd | Nucleotide sequences (mutated GDF-9B polypeptides) involved in increasing and decreasing mammalian ovulation rate |
| NZ502796A (en) * | 2000-06-15 | 2003-02-28 | Agres Ltd | Nucleotide and amino acid sequences of oocyte factors related to GDF-9B or GDF-9 |
-
2002
- 2002-05-30 NZ NZ51933002A patent/NZ519330A/xx not_active IP Right Cessation
-
2003
- 2003-05-30 EP EP03723538A patent/EP1551973A4/fr not_active Withdrawn
- 2003-05-30 AU AU2003235525A patent/AU2003235525B2/en not_active Ceased
- 2003-05-30 WO PCT/NZ2003/000109 patent/WO2003102199A1/fr active Application Filing
- 2003-05-30 CA CA002490051A patent/CA2490051A1/fr not_active Abandoned
- 2003-05-30 JP JP2004510436A patent/JP2006510345A/ja active Pending
- 2003-05-30 BR BR0311465-1A patent/BR0311465A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1551973A4 (fr) | 2006-06-07 |
| AU2003235525B2 (en) | 2008-09-11 |
| JP2006510345A (ja) | 2006-03-30 |
| BR0311465A (pt) | 2005-04-05 |
| NZ519330A (en) | 2004-12-24 |
| EP1551973A1 (fr) | 2005-07-13 |
| WO2003102199A1 (fr) | 2003-12-11 |
| AU2003235525A1 (en) | 2003-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |