CA2489165A1 - Diazabicyclononane and -decane derivatives and their use as opioid receptor ligands - Google Patents
Diazabicyclononane and -decane derivatives and their use as opioid receptor ligands Download PDFInfo
- Publication number
- CA2489165A1 CA2489165A1 CA002489165A CA2489165A CA2489165A1 CA 2489165 A1 CA2489165 A1 CA 2489165A1 CA 002489165 A CA002489165 A CA 002489165A CA 2489165 A CA2489165 A CA 2489165A CA 2489165 A1 CA2489165 A1 CA 2489165A1
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- Prior art keywords
- enantiomers
- mixture
- compound
- pharmaceutically acceptable
- pain
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P37/08—Antiallergic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Public Health (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
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- Pulmonology (AREA)
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- Otolaryngology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200201143 | 2002-07-26 | ||
| DKPA200201143 | 2002-07-26 | ||
| PCT/DK2003/000510 WO2004011468A1 (en) | 2002-07-26 | 2003-07-24 | Diazabicyclononane and -decane derivatives and their use as opioid receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2489165A1 true CA2489165A1 (en) | 2004-02-05 |
Family
ID=30775758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002489165A Abandoned CA2489165A1 (en) | 2002-07-26 | 2003-07-24 | Diazabicyclononane and -decane derivatives and their use as opioid receptor ligands |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7358243B2 (https=) |
| EP (1) | EP1527075B1 (https=) |
| JP (1) | JP4588444B2 (https=) |
| CN (1) | CN100340561C (https=) |
| AT (1) | ATE390427T1 (https=) |
| AU (1) | AU2003280306B2 (https=) |
| CA (1) | CA2489165A1 (https=) |
| DE (1) | DE60319989T2 (https=) |
| MX (1) | MXPA05001002A (https=) |
| NZ (1) | NZ537182A (https=) |
| WO (1) | WO2004011468A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20040954A1 (it) * | 2004-05-12 | 2004-08-12 | Univ Degli Studi Milano | Derivati del 3,6-diazabiciclo 3.1.i.eptano ad attivita' analgesica |
| IT1395452B1 (it) * | 2009-02-25 | 2012-09-21 | Neuroscienze Pharmaness S C A Rl | Microemulsioni |
| IT1390848B1 (it) | 2008-07-31 | 2011-10-19 | Neuroscienze Pharmaness S C A R L | Composti farmaceutici |
| EP2149370A1 (en) * | 2008-07-31 | 2010-02-03 | Neuroscienze Pharmaness S.C. A R.L. | Diazabicyclic compounds and microemulsions thereof |
| IT1390850B1 (it) * | 2008-07-31 | 2011-10-19 | Neuroscienze Pharmaness S C A R L | Microemulsioni |
| IT1394400B1 (it) | 2009-02-25 | 2012-06-15 | Neuroscienze Pharmaness S C Ar L | Composizioni farmaceutiche |
| IT1396951B1 (it) | 2009-12-18 | 2012-12-20 | Neuroscienze Pharmaness S C A R L | Composti farmaceutici |
| EP2789619A1 (en) | 2013-04-12 | 2014-10-15 | Kemotech S.r.l. | Pharmaceutical compounds wiht angiogenesis inbhibitory activity |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1274018B (it) * | 1994-02-23 | 1997-07-14 | Riace Ets | Derivati del 3,8-diazabiciclo(3.2.1.)ottano ad attivita' analgesica |
| NZ513575A (en) * | 1999-05-04 | 2003-07-25 | Neurosearch As | Heteroaryl diazabicycloalkanes useful for treating or preventing a disease or a disorder responsive to the activity of nAChR modulators |
| IT1317841B1 (it) * | 2000-02-18 | 2003-07-15 | Univ Degli Studi Milano | Derivati del 3,9-diazabiciclo(3.3.1)nonano ad attivita' analgesica. |
| WO2001072303A1 (en) | 2000-03-29 | 2001-10-04 | Research Triangle Institute | Selective ligands for the delta opioid receptor |
-
2003
- 2003-07-24 NZ NZ537182A patent/NZ537182A/en not_active IP Right Cessation
- 2003-07-24 AU AU2003280306A patent/AU2003280306B2/en not_active Ceased
- 2003-07-24 MX MXPA05001002A patent/MXPA05001002A/es active IP Right Grant
- 2003-07-24 AT AT03771053T patent/ATE390427T1/de not_active IP Right Cessation
- 2003-07-24 WO PCT/DK2003/000510 patent/WO2004011468A1/en not_active Ceased
- 2003-07-24 CA CA002489165A patent/CA2489165A1/en not_active Abandoned
- 2003-07-24 DE DE60319989T patent/DE60319989T2/de not_active Expired - Lifetime
- 2003-07-24 EP EP03771053A patent/EP1527075B1/en not_active Expired - Lifetime
- 2003-07-24 CN CNB038172828A patent/CN100340561C/zh not_active Expired - Fee Related
- 2003-07-24 JP JP2004523742A patent/JP4588444B2/ja not_active Expired - Fee Related
- 2003-07-24 US US10/521,559 patent/US7358243B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7358243B2 (en) | 2008-04-15 |
| US20050239773A1 (en) | 2005-10-27 |
| MXPA05001002A (es) | 2005-05-16 |
| EP1527075A1 (en) | 2005-05-04 |
| EP1527075B1 (en) | 2008-03-26 |
| AU2003280306B2 (en) | 2009-05-21 |
| HK1077827A1 (en) | 2006-02-24 |
| CN1668621A (zh) | 2005-09-14 |
| JP2005536522A (ja) | 2005-12-02 |
| ATE390427T1 (de) | 2008-04-15 |
| NZ537182A (en) | 2006-07-28 |
| WO2004011468A1 (en) | 2004-02-05 |
| DE60319989T2 (de) | 2008-07-17 |
| DE60319989D1 (de) | 2008-05-08 |
| AU2003280306A1 (en) | 2004-02-16 |
| CN100340561C (zh) | 2007-10-03 |
| JP4588444B2 (ja) | 2010-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued | ||
| FZDE | Discontinued |
Effective date: 20120504 |