CA2481227C - Dispositifs d'administration de medicament n,o-carboxymethylchitosane adhesif pour tissus humide et leurs procedes d'utilisation - Google Patents
Dispositifs d'administration de medicament n,o-carboxymethylchitosane adhesif pour tissus humide et leurs procedes d'utilisation Download PDFInfo
- Publication number
- CA2481227C CA2481227C CA2481227A CA2481227A CA2481227C CA 2481227 C CA2481227 C CA 2481227C CA 2481227 A CA2481227 A CA 2481227A CA 2481227 A CA2481227 A CA 2481227A CA 2481227 C CA2481227 C CA 2481227C
- Authority
- CA
- Canada
- Prior art keywords
- tissue
- nocc
- drug
- moist
- adherent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0015—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/08—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Materials Engineering (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Ophthalmology & Optometry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne des dispositifs d'administration de médicaments pour tissus humides, en particulier le tissu des muqueuses ou celui des cavités séreuses, ainsi qu'un procédé d'utilisation associé. Lesdits dispositifs, qui renferment NOCC, collent au tissu des muqueuses, facilitent une administration de médicament localisée et sont particulièrement utiles dans des dispositifs vaginaux, buccaux et oculaires.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2002/010149 WO2003082163A1 (fr) | 2002-03-28 | 2002-03-28 | Dispositifs d'administration de medicament n,o-carboxymethylchitosane adhesif pour tissus humide et leurs procedes d'utilisation |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2481227A1 CA2481227A1 (fr) | 2003-10-09 |
CA2481227C true CA2481227C (fr) | 2012-07-31 |
Family
ID=28673394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2481227A Expired - Fee Related CA2481227C (fr) | 2002-03-28 | 2002-03-28 | Dispositifs d'administration de medicament n,o-carboxymethylchitosane adhesif pour tissus humide et leurs procedes d'utilisation |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1494633A4 (fr) |
AU (1) | AU2002252565A1 (fr) |
CA (1) | CA2481227C (fr) |
WO (1) | WO2003082163A1 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2209649B1 (es) * | 2002-12-09 | 2005-03-16 | Carlos Arana Molina (Titular Al 25%) | Utilizacion de la melatonina para la higiene bucodental para uso humano y veterinario como producto activo. |
WO2009036014A2 (fr) * | 2007-09-10 | 2009-03-19 | Boston Scientific Scimed, Inc. | Dispositifs médicaux avec matériau bioadhésif susceptible d'être activé |
CN110731377B (zh) * | 2019-10-25 | 2022-08-30 | 浙江大学 | 一种羧甲基壳聚糖基褪黑素双层自组装膜及其应用方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5888988A (en) * | 1995-05-08 | 1999-03-30 | Chitogenics, Inc. | Covalently linked N,O-carboxymethylchitosan and uses thereof |
CA2193149C (fr) * | 1995-12-22 | 2002-04-23 | David H. Donabedian | Systemes cationiques therapeutiques |
US6030635A (en) * | 1998-02-27 | 2000-02-29 | Musculoskeletal Transplant Foundation | Malleable paste for filling bone defects |
US6645947B1 (en) * | 1999-05-20 | 2003-11-11 | Chitogenics, Inc. | Adhesive N, O-carboxymethylchitosan coatings which inhibit attachment of substrate-dependent cells and proteins |
AU2001276831A1 (en) * | 2000-06-22 | 2002-01-02 | Rxkinetix, Inc. | Delivery vehicle composition and methods for delivering antigens and other drugs |
-
2002
- 2002-03-28 WO PCT/US2002/010149 patent/WO2003082163A1/fr not_active Application Discontinuation
- 2002-03-28 AU AU2002252565A patent/AU2002252565A1/en not_active Abandoned
- 2002-03-28 CA CA2481227A patent/CA2481227C/fr not_active Expired - Fee Related
- 2002-03-28 EP EP02721645A patent/EP1494633A4/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1494633A1 (fr) | 2005-01-12 |
AU2002252565A1 (en) | 2003-10-13 |
WO2003082163A1 (fr) | 2003-10-09 |
CA2481227A1 (fr) | 2003-10-09 |
EP1494633A4 (fr) | 2005-09-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6809085B1 (en) | Adherent N,O-Carboxymethylchitosan drug delivery devices for moist tissue and methods of their use | |
Jin et al. | Influence of hydrophilic polymers on functional properties and wound healing efficacy of hydrocolloid based wound dressings | |
RU2453340C2 (ru) | Полимерный тканевый герметик | |
US7074424B2 (en) | Polyalkylene glycol viscosity-enhancing polymeric formulations | |
JP3628809B2 (ja) | 薬剤徐放性医療用配合物及びその製造方法 | |
Gurny et al. | Bioadhesive intraoral release systems: design, testing and analysis | |
EP1077678B1 (fr) | Compositions mucoadhesives pour l'application d'agents biologiquement actifs a des tissus animaux | |
US20100015231A1 (en) | Low swell, long-lived hydrogel sealant | |
JPH03151322A (ja) | 薬剤持続的放出性包帯材として使用する製剤 | |
JP2002541923A (ja) | 急速ゲル化生体適合性ポリマー組成物 | |
JPH02107267A (ja) | 創傷充填用組成物 | |
JP2000515401A (ja) | 接着剤およびこのような接着剤の使用 | |
JP2003517343A (ja) | 感圧接着剤組成物 | |
KR20180075601A (ko) | 복합 생체 접착성 실란트 | |
KR100416104B1 (ko) | 수용성 알긴산염과 카르복시메틸 셀룰로오스를 주성분으로하는 유착방지제 및 그의 제조방법 | |
US6652876B2 (en) | Active substance patch, kind to the skin, for transdermal administration of nonsteroidal antirheumatics | |
JP2008536998A (ja) | ヒトの皮膚に付着させる接着組成物および接着素子 | |
CA2481227C (fr) | Dispositifs d'administration de medicament n,o-carboxymethylchitosane adhesif pour tissus humide et leurs procedes d'utilisation | |
CN116744984A (zh) | 包含蛋白质和多官能化改性的基于聚乙二醇的交联剂的反应性干粉状止血材料 | |
EP1109584A1 (fr) | Composition susceptible d'absorber un fluide | |
Gurny et al. | Semisolid dosage forms as buccal bioadhesives | |
JP3157082B2 (ja) | 医療用パック型製剤用基剤および医療用パック型製剤 | |
Adikwu et al. | Evaluation of snail mucin as bioadhesive agent for the delivery of chlorpropamide | |
KR101651574B1 (ko) | 활성 약물을 함유하는 하이드로콜로이드 | |
JPH0678988A (ja) | 皮膚保護用揺変性接着ペースト、その製法およびその使用法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20150330 |