CA2476223A1 - Composes antibacteriens a base de macrolides - Google Patents

Composes antibacteriens a base de macrolides Download PDF

Info

Publication number
CA2476223A1
CA2476223A1 CA002476223A CA2476223A CA2476223A1 CA 2476223 A1 CA2476223 A1 CA 2476223A1 CA 002476223 A CA002476223 A CA 002476223A CA 2476223 A CA2476223 A CA 2476223A CA 2476223 A1 CA2476223 A1 CA 2476223A1
Authority
CA
Canada
Prior art keywords
ethyl
hydrogen
trideoxy
trioxo
xylo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002476223A
Other languages
English (en)
Inventor
Zhenkun Ma
Richard Clark
Stevan Djuric
Sanyi Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/075,011 external-priority patent/US20030171308A1/en
Application filed by Individual filed Critical Individual
Publication of CA2476223A1 publication Critical patent/CA2476223A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

La présente invention concerne des composés représentés par la formule générale (I), certains de leurs sels, promédicaments et des sels de promédicaments. L'invention concerne également des procédés de fabrication des composés et des intermédiaires utilisés pour ces procédés. L'invention concerne aussi des compositions contenant les composés. L'invention concerne enfin l'utilisation de ces composés pour des traitements prophylactiques ou thérapeutiques contre des infections bactériennes.
CA002476223A 2002-02-13 2003-02-11 Composes antibacteriens a base de macrolides Abandoned CA2476223A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10/075,011 US20030171308A1 (en) 2002-02-13 2002-02-13 Macrolide antibacterial compounds
US10/075,011 2002-02-13
US36165103A 2003-02-10 2003-02-10
US10/361,651 2003-02-10
PCT/US2003/004117 WO2003068790A2 (fr) 2002-02-13 2003-02-11 Composes antibacteriens a base de macrolides

Publications (1)

Publication Number Publication Date
CA2476223A1 true CA2476223A1 (fr) 2003-08-21

Family

ID=27736825

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002476223A Abandoned CA2476223A1 (fr) 2002-02-13 2003-02-11 Composes antibacteriens a base de macrolides

Country Status (5)

Country Link
EP (1) EP1474431A2 (fr)
JP (1) JP2005522453A (fr)
CA (1) CA2476223A1 (fr)
MX (1) MXPA04007883A (fr)
WO (1) WO2003068790A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201509006D0 (en) * 2015-05-26 2015-07-08 Redx Pharma Plc Antibacterial compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100523679B1 (ko) * 1996-09-04 2005-10-26 아보트 러보러터리즈 항균 활성을 지닌 6-ｏ-치환된 케톨라이드
CO4990960A1 (es) * 1997-10-29 2000-12-26 Abbott Lab Derivados de cetolidos 2-halo-6-o sustituidos
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity

Also Published As

Publication number Publication date
WO2003068790A3 (fr) 2003-12-04
JP2005522453A (ja) 2005-07-28
EP1474431A2 (fr) 2004-11-10
WO2003068790A2 (fr) 2003-08-21
MXPA04007883A (es) 2004-11-26

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead