CA2472570C - Aerosol generator for drug formulation - Google Patents
Aerosol generator for drug formulation Download PDFInfo
- Publication number
- CA2472570C CA2472570C CA2472570A CA2472570A CA2472570C CA 2472570 C CA2472570 C CA 2472570C CA 2472570 A CA2472570 A CA 2472570A CA 2472570 A CA2472570 A CA 2472570A CA 2472570 C CA2472570 C CA 2472570C
- Authority
- CA
- Canada
- Prior art keywords
- aerosol generator
- aerosol
- recited
- fluid
- camshaft
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000443 aerosol Substances 0.000 title claims abstract description 188
- 239000013583 drug formulation Substances 0.000 title description 7
- 239000012530 fluid Substances 0.000 claims description 90
- 239000000463 material Substances 0.000 claims description 7
- 230000007246 mechanism Effects 0.000 claims description 6
- 230000004044 response Effects 0.000 claims description 3
- 239000004973 liquid crystal related substance Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 16
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 62
- 239000003570 air Substances 0.000 description 61
- 239000003814 drug Substances 0.000 description 29
- 239000012080 ambient air Substances 0.000 description 20
- 238000009833 condensation Methods 0.000 description 11
- 230000005494 condensation Effects 0.000 description 11
- 238000010438 heat treatment Methods 0.000 description 11
- 239000007788 liquid Substances 0.000 description 11
- 229940079593 drug Drugs 0.000 description 9
- 230000000694 effects Effects 0.000 description 9
- AAAQKTZKLRYKHR-UHFFFAOYSA-N triphenylmethane Chemical compound C1=CC=CC=C1C(C=1C=CC=CC=1)C1=CC=CC=C1 AAAQKTZKLRYKHR-UHFFFAOYSA-N 0.000 description 8
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 6
- 238000004891 communication Methods 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 210000004072 lung Anatomy 0.000 description 6
- 239000002245 particle Substances 0.000 description 6
- 229940055577 oleyl alcohol Drugs 0.000 description 5
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 5
- 230000007423 decrease Effects 0.000 description 4
- 238000001514 detection method Methods 0.000 description 4
- 239000002184 metal Substances 0.000 description 4
- 229910052751 metal Inorganic materials 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 230000003213 activating effect Effects 0.000 description 3
- 230000004913 activation Effects 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 230000008021 deposition Effects 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 239000006199 nebulizer Substances 0.000 description 3
- 239000002667 nucleating agent Substances 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 239000003380 propellant Substances 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 208000007934 ACTH-independent macronodular adrenal hyperplasia Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 239000004020 conductor Substances 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 239000012052 hydrophilic carrier Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- 238000009834 vaporization Methods 0.000 description 2
- 230000008016 vaporization Effects 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000012159 carrier gas Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 230000003434 inspiratory effect Effects 0.000 description 1
- 239000012669 liquid formulation Substances 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 229910052987 metal hydride Inorganic materials 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- PXHVJJICTQNCMI-UHFFFAOYSA-N nickel Substances [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 1
- -1 nickel metal hydride Chemical class 0.000 description 1
- 230000006911 nucleation Effects 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000001141 propulsive effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000011364 vaporized material Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
- A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/008—Electronic counters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0096—Hindering inhalation before activation of the dispenser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
- A61M15/025—Bubble jet droplet ejection devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0081—Locking means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0083—Timers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
- B05B12/08—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means
- B05B12/12—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means responsive to conditions of ambient medium or target, e.g. humidity, temperature position or movement of the target relative to the spray apparatus
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Nozzles (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34787202P | 2002-01-15 | 2002-01-15 | |
| US60/347,872 | 2002-01-15 | ||
| US10/341,521 | 2003-01-14 | ||
| US10/341,521 US7458373B2 (en) | 2002-01-15 | 2003-01-14 | Aerosol generator for drug formulation |
| PCT/US2003/001048 WO2003059413A2 (en) | 2002-01-15 | 2003-01-15 | Aerosol generator for drug formulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2472570A1 CA2472570A1 (en) | 2003-07-24 |
| CA2472570C true CA2472570C (en) | 2013-02-26 |
Family
ID=26992548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2472570A Expired - Lifetime CA2472570C (en) | 2002-01-15 | 2003-01-15 | Aerosol generator for drug formulation |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7458373B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1471955B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4340155B2 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2003207547B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2472570C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2535974T3 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE025437T2 (cg-RX-API-DMAC7.html) |
| PT (1) | PT1471955E (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003059413A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004305518A1 (en) * | 2003-12-15 | 2005-07-07 | Alexza Pharmaceuticals, Inc. | Treatment of breakthrough pain by drug aerosol inhalation |
| EP1745247B1 (en) | 2004-04-23 | 2015-11-11 | Philip Morris Products S.a.s. | Aerosol generators and methods for producing aerosols |
| US20060102175A1 (en) * | 2004-11-18 | 2006-05-18 | Nelson Stephen G | Inhaler |
| EP1893273B1 (en) | 2005-05-18 | 2014-06-25 | Nektar Therapeutics | Adapter for use with aerosolization device for endobronchial therapy |
| US7186958B1 (en) * | 2005-09-01 | 2007-03-06 | Zhao Wei, Llc | Inhaler |
| WO2007034230A1 (en) * | 2005-09-26 | 2007-03-29 | University Of Leeds | Fuel injector |
| GB2433207B (en) * | 2006-02-21 | 2009-01-07 | Jianhe Li | Active suction actuated inhalers with timing devices |
| US8156933B2 (en) * | 2006-06-21 | 2012-04-17 | Puthalath Koroth Raghuprasad | Cloud nebulizer |
| WO2008008281A2 (en) | 2006-07-07 | 2008-01-17 | Proteus Biomedical, Inc. | Smart parenteral administration system |
| CN100536951C (zh) * | 2006-11-11 | 2009-09-09 | 达福堡国际有限公司 | 肺内给药装置 |
| WO2008112353A2 (en) * | 2007-02-05 | 2008-09-18 | The Brigham And Women's Hospital, Inc. | Instrumented metered-dose inhaler and methods for predicting disease exacerbations |
| US20080290114A1 (en) * | 2007-05-25 | 2008-11-27 | Honeywell International Inc. | Drug Delivery Flow Controller |
| WO2009055733A1 (en) | 2007-10-25 | 2009-04-30 | Proteus Biomedical, Inc. | Fluid transfer port information system |
| WO2009067463A1 (en) | 2007-11-19 | 2009-05-28 | Proteus Biomedical, Inc. | Body-associated fluid transport structure evaluation devices |
| EP2534957B1 (en) | 2007-12-14 | 2015-05-27 | AeroDesigns, Inc | Delivering aerosolizable products |
| US10780241B2 (en) | 2008-08-21 | 2020-09-22 | Vero Biotech LLC | Devices and methods for minimizing and treating high-altitude sickness |
| WO2010033240A2 (en) | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Carbohydrate-based drug delivery polymers and conjugates thereof |
| US20100108780A1 (en) * | 2008-10-31 | 2010-05-06 | Joshi Ashok V | Liquid atomization device and method |
| US10173019B2 (en) | 2009-12-26 | 2019-01-08 | Inspiro Medical Ltd. | Dry powder delivery device |
| SG189763A1 (en) | 2010-02-01 | 2013-05-31 | Proteus Digital Health Inc | Two-wrist data gathering system |
| EP2531099B1 (en) | 2010-02-01 | 2018-12-12 | Proteus Digital Health, Inc. | Data gathering system |
| PL2753202T3 (pl) | 2011-09-06 | 2016-11-30 | Podgrzewanie materiału przeznaczonego do palenia | |
| GB201207054D0 (en) | 2011-09-06 | 2012-06-06 | British American Tobacco Co | Heating smokeable material |
| WO2013034454A1 (en) | 2011-09-06 | 2013-03-14 | British American Tobacco (Investments) Limited | Heating smokeable material |
| EP3892125A3 (en) | 2011-09-06 | 2022-01-05 | Nicoventures Trading Limited | Heating smokable material |
| WO2013034456A1 (en) | 2011-09-06 | 2013-03-14 | British American Tobacco (Investments) Limited | Heating smokable material |
| GB201207039D0 (en) | 2012-04-23 | 2012-06-06 | British American Tobacco Co | Heating smokeable material |
| US11253661B2 (en) | 2012-06-25 | 2022-02-22 | Gecko Health Innovations, Inc. | Devices, systems, and methods for adherence monitoring and patient interaction |
| US10034988B2 (en) | 2012-11-28 | 2018-07-31 | Fontem Holdings I B.V. | Methods and devices for compound delivery |
| US9642980B2 (en) | 2013-03-15 | 2017-05-09 | Trudell Medical International | Ventilator circuit, adapter for use in ventilator circuit and methods for the use thereof |
| US9918496B2 (en) | 2013-07-24 | 2018-03-20 | Altria Client Services Llc | Electronic smoking article |
| CA2922686C (en) | 2013-08-28 | 2023-03-07 | Gecko Health Innovations, Inc. | Devices, systems, and methods for adherence monitoring and devices, systems, and methods for monitoring use of consumable dispensers |
| US10194693B2 (en) | 2013-09-20 | 2019-02-05 | Fontem Holdings 1 B.V. | Aerosol generating device |
| NZ718007A (en) | 2013-10-29 | 2017-06-30 | British American Tobacco Investments Ltd | Apparatus for heating smokable material |
| US10292424B2 (en) * | 2013-10-31 | 2019-05-21 | Rai Strategic Holdings, Inc. | Aerosol delivery device including a pressure-based aerosol delivery mechanism |
| US10286163B1 (en) | 2014-03-04 | 2019-05-14 | Philip J. Paustian | On demand aerosolized delivery inhaler |
| NO2709641T3 (cg-RX-API-DMAC7.html) | 2014-03-10 | 2018-05-12 | ||
| US10737042B2 (en) | 2014-08-26 | 2020-08-11 | Michael Edward Breede | Thermal modulation of an inhalable medicament |
| US10300228B2 (en) | 2014-08-26 | 2019-05-28 | Innovosciences, Llc | Thermal modulation of an inhalable medicament |
| GB201511349D0 (en) | 2015-06-29 | 2015-08-12 | Nicoventures Holdings Ltd | Electronic aerosol provision systems |
| GB201511361D0 (en) | 2015-06-29 | 2015-08-12 | Nicoventures Holdings Ltd | Electronic vapour provision system |
| HK1252464B (en) | 2015-07-20 | 2020-05-22 | Pearl Therapeutics, Inc. | Aerosol delivery systems |
| US11924930B2 (en) | 2015-08-31 | 2024-03-05 | Nicoventures Trading Limited | Article for use with apparatus for heating smokable material |
| US20170055584A1 (en) | 2015-08-31 | 2017-03-02 | British American Tobacco (Investments) Limited | Article for use with apparatus for heating smokable material |
| US20170119046A1 (en) | 2015-10-30 | 2017-05-04 | British American Tobacco (Investments) Limited | Apparatus for Heating Smokable Material |
| KR102661607B1 (ko) | 2015-11-02 | 2024-04-30 | 필립모리스 프로덕츠 에스.에이. | 진동 부재를 포함하는 에어로졸 발생 시스템 |
| WO2017192773A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Methods for treatment of pulmonary lung diseases with improved therapeutic efficacy and improved dose efficiency |
| WO2017192774A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Methods for the systemic delivery of therapeutic agents to the pulmonary system using a droplet delivery device |
| EP3452150B1 (en) | 2016-05-03 | 2024-01-17 | Pneuma Respiratory, Inc. | Droplet delivery device for delivery of fluids to the pulmonary system |
| EP3452152B1 (en) | 2016-05-03 | 2025-07-02 | Pneuma Respiratory, Inc. | A droplet delivery device for generating and delivering droplets to the pulmonary system |
| WO2017192782A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment |
| GB201612945D0 (en) | 2016-07-26 | 2016-09-07 | British American Tobacco Investments Ltd | Method of generating aerosol |
| WO2018029536A1 (en) * | 2016-08-10 | 2018-02-15 | Gary Stephen Shuster | Vaporization improvements |
| EP4223335A3 (en) | 2017-05-19 | 2023-11-08 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
| WO2018216019A1 (en) * | 2017-05-25 | 2018-11-29 | Ian Solomon | Apparatus for delivering a liquid aerosol to oral cavity surfaces |
| GB2564407A (en) * | 2017-07-06 | 2019-01-16 | Corefox Oy | Portable inhalator device |
| JP2020536614A (ja) | 2017-10-04 | 2020-12-17 | ニューマ・リスパイラトリー・インコーポレイテッド | 呼吸により電気的に作動するインライン液滴送達装置および使用方法 |
| CA3079189A1 (en) | 2017-10-17 | 2019-04-25 | Pneuma Respiratory, Inc. | Nasal drug delivery apparatus and methods of use |
| JP2021502178A (ja) | 2017-11-08 | 2021-01-28 | ニューマ・リスパイラトリー・インコーポレイテッド | 小容積アンプルを有して呼吸により電気的に作動するインライン液滴送達装置および使用方法 |
| US11698717B2 (en) | 2018-06-15 | 2023-07-11 | Juul Labs, Inc. | Session control for a vaporizer device |
| GB201814197D0 (en) | 2018-08-31 | 2018-10-17 | Nicoventures Trading Ltd | Aerosol generating material characteristic determination |
| EP3863436B1 (en) | 2018-10-08 | 2024-12-04 | Juul Labs, Inc. | Cartridge for a vaporizer device and vaporizer device |
| WO2020082040A1 (en) | 2018-10-19 | 2020-04-23 | Juul Labs, Inc. | Charging adapter for vaporizer device |
| WO2020176777A1 (en) * | 2019-02-28 | 2020-09-03 | Nano Vape Corporation | Inhalable vapor generation method and system |
| AU2020308104B2 (en) * | 2019-06-27 | 2025-06-19 | Pneuma Respiratory, Inc. | Delivery of small droplets to the respiratory system via electronic breath actuated droplet delivery device |
| US11355808B2 (en) * | 2019-12-16 | 2022-06-07 | Turner Imaging Systems, Inc. | Power source for portable medical devices |
| WO2021224923A1 (en) * | 2020-05-05 | 2021-11-11 | Hospitech Respiration Ltd. | Fluid distribution device |
| JP1714440S (ja) | 2020-10-30 | 2022-05-10 | 喫煙用エアロゾル発生器 | |
| JP1715888S (ja) | 2020-10-30 | 2022-05-25 | 喫煙用エアロゾル発生器 | |
| JP1714443S (ja) | 2020-10-30 | 2022-05-10 | 喫煙用エアロゾル発生器 | |
| JP1714442S (ja) | 2020-10-30 | 2022-05-10 | 喫煙用エアロゾル発生器 | |
| JP1714441S (ja) | 2020-10-30 | 2022-05-10 | 喫煙用エアロゾル発生器 | |
| USD990765S1 (en) | 2020-10-30 | 2023-06-27 | Nicoventures Trading Limited | Aerosol generator |
| USD989384S1 (en) | 2021-04-30 | 2023-06-13 | Nicoventures Trading Limited | Aerosol generator |
| PL4359046T3 (pl) | 2021-06-22 | 2025-10-13 | Pneuma Respiratory, Inc. | Urządzenie do podawania kropelkowego z wyrzutem wypychającym |
| US12161795B2 (en) | 2022-07-18 | 2024-12-10 | Pneuma Respiratory, Inc. | Small step size and high resolution aerosol generation system and method |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3716416A (en) * | 1971-05-20 | 1973-02-13 | Engelhard Min & Chem | Fuel metering device for fuel cell |
| SE408265B (sv) * | 1975-12-12 | 1979-06-05 | Draco Ab | Anordning for koldioxiddriven endosaerosol, avsedd for inhalering |
| GB2129691B (en) * | 1982-10-08 | 1987-08-05 | Glaxo Group Ltd | Devices for administering medicaments to patients |
| AU591152B2 (en) * | 1985-07-30 | 1989-11-30 | Glaxo Group Limited | Devices for administering medicaments to patients |
| AU9089591A (en) * | 1990-12-17 | 1992-07-22 | Minnesota Mining And Manufacturing Company | Inhaler |
| AU6130394A (en) * | 1991-03-05 | 1994-08-15 | Miris Medical Corporation | Apparatus for providing a timed release of an amount of aerosol medication |
| US5363842A (en) * | 1991-12-20 | 1994-11-15 | Circadian, Inc. | Intelligent inhaler providing feedback to both patient and medical professional |
| EP0706352B1 (en) * | 1993-06-29 | 2002-03-20 | Ponwell Enterprises Limited | Dispenser |
| DE4409073A1 (de) * | 1994-03-17 | 1995-09-28 | Harald Prof Dr Berndt | Vorrichtung zum Handhabung von Flüssigkeiten für analytische Zwecke |
| WO1997002857A1 (en) * | 1995-07-10 | 1997-01-30 | A & D Company, Limited | Atomizer |
| ES2216418T3 (es) * | 1995-12-07 | 2004-10-16 | Jago Research Ag | Boquilla para un inhalador para la administracion de varias dosis de un polvo seco farmacologico. |
| US5839430A (en) * | 1996-04-26 | 1998-11-24 | Cama; Joseph | Combination inhaler and peak flow rate meter |
| US5743251A (en) * | 1996-05-15 | 1998-04-28 | Philip Morris Incorporated | Aerosol and a method and apparatus for generating an aerosol |
| US5906202A (en) * | 1996-11-21 | 1999-05-25 | Aradigm Corporation | Device and method for directing aerosolized mist to a specific area of the respiratory tract |
| US5794612A (en) * | 1997-04-02 | 1998-08-18 | Aeromax Technologies, Inc. | MDI device with ultrasound sensor to detect aerosol dispensing |
| KR100289448B1 (ko) * | 1997-07-23 | 2001-05-02 | 미즈노 마사루 | 향미발생장치 |
| US5855564A (en) * | 1997-08-20 | 1999-01-05 | Aradigm Corporation | Aerosol extrusion mechanism |
| US6152130A (en) * | 1998-06-12 | 2000-11-28 | Microdose Technologies, Inc. | Inhalation device with acoustic control |
| US6260549B1 (en) * | 1998-06-18 | 2001-07-17 | Clavius Devices, Inc. | Breath-activated metered-dose inhaler |
| EP1107810B1 (en) * | 1998-08-28 | 2005-11-09 | Glaxo Group Limited | Dispenser |
| US6234167B1 (en) * | 1998-10-14 | 2001-05-22 | Chrysalis Technologies, Incorporated | Aerosol generator and methods of making and using an aerosol generator |
| US6070575A (en) * | 1998-11-16 | 2000-06-06 | Aradigm Corporation | Aerosol-forming porous membrane with certain pore structure |
| WO2003095005A1 (en) * | 2002-05-10 | 2003-11-20 | Chrysalis Technologies Incorporated | Aerosol generator for drug formulation and methods of generating aerosol |
-
2003
- 2003-01-14 US US10/341,521 patent/US7458373B2/en not_active Expired - Lifetime
- 2003-01-15 JP JP2003559573A patent/JP4340155B2/ja not_active Expired - Lifetime
- 2003-01-15 WO PCT/US2003/001048 patent/WO2003059413A2/en not_active Ceased
- 2003-01-15 AU AU2003207547A patent/AU2003207547B2/en not_active Ceased
- 2003-01-15 EP EP03705758.5A patent/EP1471955B1/en not_active Expired - Lifetime
- 2003-01-15 PT PT3705758T patent/PT1471955E/pt unknown
- 2003-01-15 CA CA2472570A patent/CA2472570C/en not_active Expired - Lifetime
- 2003-01-15 HU HUE03705758A patent/HUE025437T2/en unknown
- 2003-01-15 ES ES03705758.5T patent/ES2535974T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US7458373B2 (en) | 2008-12-02 |
| HUE025437T2 (en) | 2016-05-30 |
| WO2003059413A2 (en) | 2003-07-24 |
| CA2472570A1 (en) | 2003-07-24 |
| PT1471955E (pt) | 2015-04-27 |
| US20030230303A1 (en) | 2003-12-18 |
| JP4340155B2 (ja) | 2009-10-07 |
| EP1471955A2 (en) | 2004-11-03 |
| WO2003059413A3 (en) | 2003-11-13 |
| ES2535974T3 (es) | 2015-05-19 |
| EP1471955B1 (en) | 2015-03-04 |
| AU2003207547A1 (en) | 2003-07-30 |
| EP1471955A4 (en) | 2010-11-03 |
| JP2006501871A (ja) | 2006-01-19 |
| AU2003207547B2 (en) | 2008-07-03 |
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