CA2468790A1 - Chemokine mutants acting as chemokine antagonists - Google Patents
Chemokine mutants acting as chemokine antagonists Download PDFInfo
- Publication number
- CA2468790A1 CA2468790A1 CA002468790A CA2468790A CA2468790A1 CA 2468790 A1 CA2468790 A1 CA 2468790A1 CA 002468790 A CA002468790 A CA 002468790A CA 2468790 A CA2468790 A CA 2468790A CA 2468790 A1 CA2468790 A1 CA 2468790A1
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- CA
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- Prior art keywords
- chemokine
- mutants
- rantes
- amino acid
- mutant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01000761 | 2001-12-17 | ||
| EP01000761.5 | 2001-12-17 | ||
| PCT/EP2002/014325 WO2003051921A1 (en) | 2001-12-17 | 2002-12-16 | Chemokine mutants acting as chemokine antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2468790A1 true CA2468790A1 (en) | 2003-06-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CA002468790A Abandoned CA2468790A1 (en) | 2001-12-17 | 2002-12-16 | Chemokine mutants acting as chemokine antagonists |
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| Country | Link |
|---|---|
| US (1) | US7553483B2 (enExample) |
| EP (1) | EP1458756B1 (enExample) |
| JP (1) | JP2005525089A (enExample) |
| AT (1) | ATE421974T1 (enExample) |
| AU (1) | AU2002358144B2 (enExample) |
| CA (1) | CA2468790A1 (enExample) |
| DE (1) | DE60231057D1 (enExample) |
| ES (1) | ES2320743T3 (enExample) |
| IL (1) | IL162600A0 (enExample) |
| WO (1) | WO2003051921A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023057589A1 (en) | 2021-10-06 | 2023-04-13 | Virothera Ltd | Novel immune regulator |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2507008A1 (en) * | 2002-12-23 | 2004-07-29 | Applied Research Systems Ars Holding N.V. | Use of cc-chemokine mutants against liver diseases |
| ATE322506T1 (de) * | 2004-01-19 | 2006-04-15 | Ares Trading Sa | Verfahren zur reinigung von in bakterien exprimierten proteinen |
| WO2008134020A1 (en) * | 2007-04-26 | 2008-11-06 | University Of Vermont And State Agricultural College | Ccl18 and ccl3 methods and compositions for detecting and treating cancer |
| EP2185719B1 (en) | 2007-08-02 | 2013-11-13 | NovImmune SA | Anti-rantes antibodies and methods of use thereof |
| WO2010071610A1 (en) * | 2008-12-19 | 2010-06-24 | Agency For Science, Technology And Research (A*Star) | Severe chikungunya biomarkers |
| EP2380975A1 (de) * | 2010-04-22 | 2011-10-26 | Scil Proteins GmbH | Verfahren zur Herstellung von rekombinantem Thrombin |
| US9352000B2 (en) * | 2010-05-05 | 2016-05-31 | Rappaport Family Institute For Research In The Medical Sciences | Use of CCL1 in therapy |
| US9717777B2 (en) | 2010-05-05 | 2017-08-01 | Rappaport Family Institute For Research In The Medical Sciences | Use of CCL1 in therapy |
| EP3307330B1 (en) * | 2015-06-15 | 2021-03-10 | New York University | Method of treatment using oncolytic viruses |
| WO2017077062A1 (en) * | 2015-11-05 | 2017-05-11 | Ludwig-Maximilians-Universität München | A peptide derived from human neutrophile peptide 1 |
| KR102682118B1 (ko) * | 2016-04-29 | 2024-07-08 | 주식회사유한양행 | Ccl3 변이체를 포함하는 융합 단백질 및 이의 용도 |
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| AU679436B2 (en) * | 1991-12-23 | 1997-07-03 | British Bio-Technology Limited | Stem cell inhibiting proteins |
| HU221089B1 (en) * | 1994-12-08 | 2002-08-28 | Glaxo Group Ltd | Rantes peptide derivates with antagonistic effect and uses thereof |
| JP2001506492A (ja) * | 1996-12-05 | 2001-05-22 | ヒューマン ゲノム サイエンシズ インク． | ヒトケモカインβ−１３ |
| AU5137698A (en) | 1996-12-05 | 1998-06-29 | Kyowa Hakko Kogyo Co. Ltd. | Novel dna, novel protein, and novel antibody |
| EP0906954A1 (en) | 1997-09-29 | 1999-04-07 | Applied Research Systems ARS Holding N.V. | Amino-terminal truncated c-c chemokines as chemokine antagonist |
| CA2316447C (en) | 1997-12-23 | 2009-07-28 | Fondazione Centro San Raffaele Del Monte Tabor | Rantes mutants and therapeutic applications thereof |
| JPH11243960A (ja) * | 1998-03-06 | 1999-09-14 | Shionogi & Co Ltd | ヒトｃｃ型ケモカインエオタキシン３ |
| WO2000004926A2 (en) * | 1998-07-22 | 2000-02-03 | Osprey Pharmaceuticals Limited | Conjugates for treating inflammatory disorders and associated tissue damage |
| WO2000078334A1 (en) * | 1999-06-17 | 2000-12-28 | University Of Maryland Biotechnology Institute | Chimeric chemokine-antigen polypeptides and uses therefor |
| US6926898B2 (en) | 2000-04-12 | 2005-08-09 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| UA77950C2 (en) | 2000-10-04 | 2007-02-15 | Applied Research Systems | Use of mutants of cc chemokines for treatment of multiple sclerosis |
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2002
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- 2002-12-16 IL IL16260002A patent/IL162600A0/xx unknown
- 2002-12-16 AU AU2002358144A patent/AU2002358144B2/en not_active Ceased
- 2002-12-16 DE DE60231057T patent/DE60231057D1/de not_active Expired - Lifetime
- 2002-12-16 JP JP2003552801A patent/JP2005525089A/ja active Pending
- 2002-12-16 CA CA002468790A patent/CA2468790A1/en not_active Abandoned
- 2002-12-16 AT AT02791832T patent/ATE421974T1/de not_active IP Right Cessation
- 2002-12-16 WO PCT/EP2002/014325 patent/WO2003051921A1/en not_active Ceased
- 2002-12-16 ES ES02791832T patent/ES2320743T3/es not_active Expired - Lifetime
- 2002-12-16 EP EP02791832A patent/EP1458756B1/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023057589A1 (en) | 2021-10-06 | 2023-04-13 | Virothera Ltd | Novel immune regulator |
Also Published As
| Publication number | Publication date |
|---|---|
| DE60231057D1 (de) | 2009-03-19 |
| US20050220757A1 (en) | 2005-10-06 |
| EP1458756A1 (en) | 2004-09-22 |
| WO2003051921A1 (en) | 2003-06-26 |
| AU2002358144B2 (en) | 2008-10-02 |
| ES2320743T3 (es) | 2009-05-28 |
| JP2005525089A (ja) | 2005-08-25 |
| AU2002358144A1 (en) | 2003-06-30 |
| US7553483B2 (en) | 2009-06-30 |
| IL162600A0 (en) | 2005-11-20 |
| ATE421974T1 (de) | 2009-02-15 |
| EP1458756B1 (en) | 2009-01-28 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |