CA2460042C - Inhibition de la presentation de l'antigene avec des polymeres faiblement catabolises - Google Patents
Inhibition de la presentation de l'antigene avec des polymeres faiblement catabolises Download PDFInfo
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- CA2460042C CA2460042C CA2460042A CA2460042A CA2460042C CA 2460042 C CA2460042 C CA 2460042C CA 2460042 A CA2460042 A CA 2460042A CA 2460042 A CA2460042 A CA 2460042A CA 2460042 C CA2460042 C CA 2460042C
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/721—Dextrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
L'invention concerne des méthodes de prévention du rejet de tissus immunogéniques chez un animal par administration d'une molécule non immunogénique faiblement catabolisée en une quantité suffisante pour inhiber une réponse immunitaire. L'invention concerne également des compositions utilisées pour inhiber les réponses immunitaires chez des animaux receveurs de transplants cellulaires. Ces méthodes et ces compositions peuvent être utilisées par exemple pour prévenir le rejet de tissus xénogreffés et allogreffés chez un animal.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23532100P | 2000-09-26 | 2000-09-26 | |
| US60/235,321 | 2000-09-26 | ||
| PCT/US2001/042329 WO2002026240A2 (fr) | 2000-09-26 | 2001-09-25 | Inhibition de la presentation de l'antigene avec des polymeres faiblement catabolises |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2460042A1 CA2460042A1 (fr) | 2002-04-04 |
| CA2460042C true CA2460042C (fr) | 2012-05-08 |
Family
ID=22885010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2460042A Expired - Fee Related CA2460042C (fr) | 2000-09-26 | 2001-09-25 | Inhibition de la presentation de l'antigene avec des polymeres faiblement catabolises |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US7538097B2 (fr) |
| AU (1) | AU2001296915A1 (fr) |
| CA (1) | CA2460042C (fr) |
| WO (1) | WO2002026240A2 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7538097B2 (en) * | 2000-09-26 | 2009-05-26 | Halozyme, Inc. | Inhibition of antigen presentation with poorly catabolized polymers |
| WO2006096164A1 (fr) | 2005-03-03 | 2006-09-14 | Allergan, Inc. | Milieux pour bacteries clostridium et procede permettant d'obtenir une toxine clostridiale |
| JP2010519211A (ja) * | 2007-02-15 | 2010-06-03 | アラーガン、インコーポレイテッド | 膀胱もしくは前立腺障害または多汗症を処置するためのボツリヌス毒素および酵素の使用 |
| TWI489994B (zh) * | 2008-03-17 | 2015-07-01 | Baxter Healthcare Sa | 供免疫球蛋白及玻尿酸酶之皮下投藥之用的組合及方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4160452A (en) * | 1977-04-07 | 1979-07-10 | Alza Corporation | Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina |
| US4256108A (en) * | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) * | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| IL88554A0 (en) | 1988-12-01 | 1989-07-31 | Hadassah Med Org | Compositions containing a compound binding to a heparin receptor |
| FR2651436B1 (fr) | 1989-09-05 | 1994-09-09 | Sanofi Sa | Compositions pharmaceutiques contenant un derive substitue soluble de dextrane. |
| FR2657782B1 (fr) | 1990-02-06 | 1992-05-22 | Therapeutiques Substitutives | Nouvel agent antitumoral derive du dextrane. |
| FR2718026B1 (fr) * | 1994-03-30 | 1997-01-17 | Paris Val Marne Universite | Médicament et composition pharmaceutique pour le traitement des muscles. |
| ATE425758T1 (de) | 1997-12-09 | 2009-04-15 | Biomed Frontiers Inc | Modifizierte polysaccharide mit veranderter biologischer erkennung |
| FR2794976B1 (fr) | 1999-06-16 | 2004-05-07 | Solutions | Compositions pharmaceutiques a action cicatrisante ou anti-complementaire comprenant un derive de dextrane |
| US20030212021A1 (en) * | 2001-01-25 | 2003-11-13 | Frost Gregory I. | Myeloid colony stimulating factor and uses thereof |
| US7538097B2 (en) * | 2000-09-26 | 2009-05-26 | Halozyme, Inc. | Inhibition of antigen presentation with poorly catabolized polymers |
-
2001
- 2001-09-25 US US10/381,855 patent/US7538097B2/en not_active Expired - Fee Related
- 2001-09-25 CA CA2460042A patent/CA2460042C/fr not_active Expired - Fee Related
- 2001-09-25 WO PCT/US2001/042329 patent/WO2002026240A2/fr active Application Filing
- 2001-09-25 AU AU2001296915A patent/AU2001296915A1/en not_active Abandoned
-
2009
- 2009-05-08 US US12/463,315 patent/US7786096B2/en not_active Expired - Fee Related
-
2010
- 2010-08-31 US US12/872,620 patent/US20100331279A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7786096B2 (en) | 2010-08-31 |
| CA2460042A1 (fr) | 2002-04-04 |
| US7538097B2 (en) | 2009-05-26 |
| US20100331279A1 (en) | 2010-12-30 |
| WO2002026240A2 (fr) | 2002-04-04 |
| US20040047874A1 (en) | 2004-03-11 |
| AU2001296915A1 (en) | 2002-04-08 |
| WO2002026240A3 (fr) | 2002-06-06 |
| US20090215722A1 (en) | 2009-08-27 |
| WO2002026240A9 (fr) | 2003-02-06 |
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