CA2459713C - Compositions and methods for priming monocytic dendritic cells and t cells for th-1 response - Google Patents
Compositions and methods for priming monocytic dendritic cells and t cells for th-1 response Download PDFInfo
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- CA2459713C CA2459713C CA2459713A CA2459713A CA2459713C CA 2459713 C CA2459713 C CA 2459713C CA 2459713 A CA2459713 A CA 2459713A CA 2459713 A CA2459713 A CA 2459713A CA 2459713 C CA2459713 C CA 2459713C
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| AT412145B (de) * | 2002-09-13 | 2004-10-25 | Forsch Krebskranke Kinder | Verfahren zur herstellung eines zellulären immuntherapeutikums auf basis von il-12-freisetzenden dendritischen zellen |
| US20040057935A1 (en) * | 2002-09-20 | 2004-03-25 | Cedars-Sinai Medical Center | Intratumoral delivery of dendritic cells |
| CN1738619B (zh) * | 2002-12-06 | 2012-04-18 | 西北生物治疗药物公司 | 给予体外部分成熟的树突细胞治疗肿瘤的制药用途 |
| US8389278B2 (en) * | 2003-02-27 | 2013-03-05 | Northwest Biotherapeutics, Inc. | Generation of dendritic cells from monocytic dendritic precursor cells with GM-CSF in the absence of additional cytokines |
| EP1484064A1 (en) | 2003-06-04 | 2004-12-08 | Gesellschaft für Biotechnologische Forschung | Therapeutical composition containing dentritic cells and use thereof |
| JP2007507543A (ja) * | 2003-10-06 | 2007-03-29 | セダーズ−シナイ メディカル センター | 樹状細胞治療によって誘導されるｔ細胞アネルギーを予防するためのｃｏｘ−２インヒビターの使用 |
| US7939090B2 (en) * | 2003-10-21 | 2011-05-10 | Cedars-Sinai Medical Center | System and method for the treatment of cancer, including cancers of the central nervous system |
| CA2544786A1 (en) * | 2003-11-04 | 2005-05-12 | Dnavec Research Inc. | Method for producing gene transferred dendritic cells |
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| CN103589684A (zh) * | 2005-12-08 | 2014-02-19 | 西北生物治疗药物公司 | 用于诱导未成熟单核细胞的树突细胞的激活的组合物和方法 |
| EP1840206A1 (en) * | 2006-03-28 | 2007-10-03 | Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh | Compositions for the preparation of mature dendritic cells |
| EP2084267B1 (en) * | 2006-09-26 | 2018-04-11 | Cedars-Sinai Medical Center | Cancer stem cell antigen vaccines and methods |
| WO2008039969A2 (en) | 2006-09-28 | 2008-04-03 | Cedars-Sinai Medical Center | Cancer vaccines and vaccination methods |
| US9068020B2 (en) * | 2008-09-02 | 2015-06-30 | Cedars-Sinai Medical Center | CD133 epitopes |
| EP2427485B1 (en) * | 2009-05-07 | 2016-12-07 | ImmunoCellular Therapeutics, Ltd. | Cd133 epitopes |
| US20150064217A1 (en) * | 2012-02-02 | 2015-03-05 | California Stem Cell, Inc. | Pluripotent germ layer origin antigen presenting cancer vaccine |
| EP2857498B1 (en) * | 2012-05-31 | 2018-04-25 | JW Creagene Inc. | Composition for maturing dendritic cells, and method for preparing antigen-specific dendritic cells using same |
| AU2020203845C1 (en) * | 2012-09-06 | 2022-08-11 | Orbis Health Solutions, Llc | Tumor lysate loaded particles |
| US9744193B2 (en) * | 2012-09-06 | 2017-08-29 | Orbis Health Solutions Llc | Tumor lysate loaded particles |
| CN104981258B (zh) | 2012-12-12 | 2017-10-20 | 奥比思健康解决方案有限责任公司 | 用于组织再生的组合物、其制备方法及其用途 |
| CA2898474A1 (en) | 2013-02-14 | 2014-08-21 | Immunocellular Therapeutics, Ltd. | Cancer vaccines and vaccination methods |
| CN104936612B (zh) * | 2013-09-05 | 2021-01-01 | 奥比思健康解决方案有限责任公司 | 装载了肿瘤裂解物的微粒 |
| EP3113759B1 (en) | 2014-03-05 | 2021-05-12 | Orbis Health Solutions LLC | Vaccine delivery systems using yeast cell wall particles |
| US9972054B1 (en) | 2014-05-20 | 2018-05-15 | State Farm Mutual Automobile Insurance Company | Accident fault determination for autonomous vehicles |
| US9754325B1 (en) | 2014-05-20 | 2017-09-05 | State Farm Mutual Automobile Insurance Company | Autonomous vehicle operation feature monitoring and evaluation of effectiveness |
| US10373259B1 (en) | 2014-05-20 | 2019-08-06 | State Farm Mutual Automobile Insurance Company | Fully autonomous vehicle insurance pricing |
| US10599155B1 (en) | 2014-05-20 | 2020-03-24 | State Farm Mutual Automobile Insurance Company | Autonomous vehicle operation feature monitoring and evaluation of effectiveness |
| US11669090B2 (en) | 2014-05-20 | 2023-06-06 | State Farm Mutual Automobile Insurance Company | Autonomous vehicle operation feature monitoring and evaluation of effectiveness |
| US11030696B1 (en) | 2014-07-21 | 2021-06-08 | State Farm Mutual Automobile Insurance Company | Methods of providing insurance savings based upon telematics and anonymous driver data |
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| EP3317403B1 (en) * | 2015-06-30 | 2025-03-05 | NorthWest Biotherapeutics, Inc. | Optimally activated dendritic cells that induce an improved or increased anti-tumor immune response |
| EP3317402B1 (en) | 2015-06-30 | 2024-02-14 | Universidade Nova de Lisboa | A viable cell population, method for production and uses thereof |
| US9805601B1 (en) | 2015-08-28 | 2017-10-31 | State Farm Mutual Automobile Insurance Company | Vehicular traffic alerts for avoidance of abnormal traffic conditions |
| US10324463B1 (en) | 2016-01-22 | 2019-06-18 | State Farm Mutual Automobile Insurance Company | Autonomous vehicle operation adjustment based upon route |
| US10395332B1 (en) | 2016-01-22 | 2019-08-27 | State Farm Mutual Automobile Insurance Company | Coordinated autonomous vehicle automatic area scanning |
| US10384678B1 (en) | 2016-01-22 | 2019-08-20 | State Farm Mutual Automobile Insurance Company | Autonomous vehicle action communications |
| US11719545B2 (en) | 2016-01-22 | 2023-08-08 | Hyundai Motor Company | Autonomous vehicle component damage and salvage assessment |
| US11242051B1 (en) | 2016-01-22 | 2022-02-08 | State Farm Mutual Automobile Insurance Company | Autonomous vehicle action communications |
| US10134278B1 (en) | 2016-01-22 | 2018-11-20 | State Farm Mutual Automobile Insurance Company | Autonomous vehicle application |
| US11441916B1 (en) | 2016-01-22 | 2022-09-13 | State Farm Mutual Automobile Insurance Company | Autonomous vehicle trip routing |
| KR102038114B1 (ko) * | 2016-02-26 | 2019-10-30 | 주식회사 엘지화학 | 광학 점착제용 (메타)아크릴레이트기 함유 벤조페논의 제조방법 및 광학 점착제 조성물 |
| WO2018160666A1 (en) * | 2017-02-28 | 2018-09-07 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Short-term activated dc1s and methods for their production and use |
| WO2019183924A1 (en) * | 2018-03-30 | 2019-10-03 | Syz Cell Therapy Co. | Improved multiple antigen specific cell therapy methods |
| WO2021071977A1 (en) * | 2019-10-07 | 2021-04-15 | Northwest Biotherapeutics, Inc. | In vitro methods and compositions for enhancing the activation of dendritic cells and t cells, and for inducing a th-1 immune response |
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| US5366866A (en) * | 1991-07-25 | 1994-11-22 | Duke University | Method of diagnosing ovarian and endometrial cancer with monoclonal antibodies OXA and OXB |
| US5227471A (en) * | 1992-01-30 | 1993-07-13 | Eastern Virginia Medical School Of The Medical College Of Hampton Roads | Monoclonal antibody PD41 that binds to a prostate mucin antigen that is expressed in human prostatic carcinoma |
| US5788963A (en) | 1995-07-31 | 1998-08-04 | Pacific Northwest Cancer Foundation | Isolation and/or preservation of dendritic cells for prostate cancer immunotherapy |
| BR9610802A (pt) * | 1995-10-04 | 1999-07-13 | Immunex Corp | Método para melhoria da resposta imunológica método de preparo de células t de antígeno específico método para induzir tolerância de tecido de enxerto auxiliar de vacina meio de expansão e preparação de células dentríticas população de células dentríticas e respectivo método de preparo método para direcionar células-tronco hematopoiéticas ou células progenitoras a uma linhagem de células dentríticas |
| US7659119B2 (en) * | 1996-02-12 | 2010-02-09 | Argos Therapeutics, Inc. | Method and compositions for obtaining mature dendritic cells |
| US6274378B1 (en) * | 1997-10-27 | 2001-08-14 | The Rockefeller University | Methods and compositions for obtaining mature dendritic cells |
| JP2000143534A (ja) * | 1998-11-13 | 2000-05-23 | Asahi Chem Ind Co Ltd | 樹状細胞ワクチン及びその製造方法 |
| JP2000279181A (ja) * | 1999-04-01 | 2000-10-10 | Japan Science & Technology Corp | ヒト樹状細胞の発現遺伝子群 |
| US20030108527A1 (en) * | 1999-12-28 | 2003-06-12 | Tsukasa Seya | Maturation-promoting agent for immature dendrtic cells |
| US6247378B1 (en) * | 2000-01-06 | 2001-06-19 | Deere & Company | Operator control device for an infinitely variable transmission |
| NZ522807A (en) * | 2000-05-12 | 2004-11-26 | Northwest Biotherapeutics Inc | Method to increase class I presentation of exogenous antigens by human dendritic cells |
| ATE317428T1 (de) * | 2001-01-15 | 2006-02-15 | Idm Immuno Designed Molecules | Verfahren zur herstellung von submikropartikel- suspensionen pharmazeutischer substanzen |
| WO2003010292A2 (en) * | 2001-07-25 | 2003-02-06 | Northwest Biotherapeutics, Inc. | Methods and apparatus for enrichment and culture of monocytic dendritic cell precursors |
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