CA2456882A1 - Modified cyclic nucleotide gated ion channel (cng) comprising methionine or valine substitutions at t537 and uses thereof - Google Patents

Modified cyclic nucleotide gated ion channel (cng) comprising methionine or valine substitutions at t537 and uses thereof Download PDF

Info

Publication number
CA2456882A1
CA2456882A1 CA002456882A CA2456882A CA2456882A1 CA 2456882 A1 CA2456882 A1 CA 2456882A1 CA 002456882 A CA002456882 A CA 002456882A CA 2456882 A CA2456882 A CA 2456882A CA 2456882 A1 CA2456882 A1 CA 2456882A1
Authority
CA
Canada
Prior art keywords
leu
glu
ala
lys
ile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CA002456882A
Other languages
English (en)
French (fr)
Inventor
Ulrich B. Kaupp
Reinhardt Seifert
Renate Gauss
Heinz-Gerd Korschen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forschungszentrum Juelich GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2456882A1 publication Critical patent/CA2456882A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002456882A 2001-08-08 2002-08-06 Modified cyclic nucleotide gated ion channel (cng) comprising methionine or valine substitutions at t537 and uses thereof Withdrawn CA2456882A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10138876A DE10138876B4 (de) 2001-08-08 2001-08-08 Genetisch modifizierte zyklisch-Nukleotid-gesteuerte lonenkanäle und deren Verwendung
DE10138876.4 2001-08-08
PCT/EP2002/008756 WO2003014149A2 (de) 2001-08-08 2002-08-06 Genetisch modifizierte zyklisch-nukleotid-gesteuerte ionenkanäle und deren verwendung

Publications (1)

Publication Number Publication Date
CA2456882A1 true CA2456882A1 (en) 2003-02-20

Family

ID=7694756

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002456882A Withdrawn CA2456882A1 (en) 2001-08-08 2002-08-06 Modified cyclic nucleotide gated ion channel (cng) comprising methionine or valine substitutions at t537 and uses thereof

Country Status (6)

Country Link
US (2) US7417117B2 (enExample)
EP (1) EP1414850B1 (enExample)
JP (1) JP4304064B2 (enExample)
CA (1) CA2456882A1 (enExample)
DE (1) DE10138876B4 (enExample)
WO (1) WO2003014149A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100056762A1 (en) 2001-05-11 2010-03-04 Old Lloyd J Specific binding proteins and uses thereof
DK1392359T4 (da) 2001-05-11 2013-06-10 Ludwig Inst For Cancer Res Ltd Specifikke bindingsproteiner og deres anvendelser.
DE10138876B4 (de) * 2001-08-08 2008-11-06 Forschungszentrum Jülich GmbH Genetisch modifizierte zyklisch-Nukleotid-gesteuerte lonenkanäle und deren Verwendung
DE10311769A1 (de) * 2003-03-18 2004-09-30 Bayer Healthcare Ag Testmethoden zur Bestimmung der intrazellulären Konzentration zyklischer Nukleotide
ES2642262T3 (es) * 2009-06-30 2017-11-16 Otsuka Pharmaceutical Co., Ltd. Método de análisis biologico para anticuerpo contra el receptor de la hormona estimuladora tiroidea, kit de medición para el anticuerpo, y célula modificada genéticamente novedosa para su uso en el método de análisis biológico o en el kit de medición
SG191354A1 (en) * 2010-12-24 2013-07-31 Otsuka Pharma Co Ltd Bioassay method for detecting physiologically active substance

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001581A (en) 1993-06-04 1999-12-14 Sibia Neurosciences, Inc. Cation-based bioassay using human metabotropic glutamate receptors
AU7902398A (en) 1997-06-13 1999-01-04 Allelix Biopharmaceuticals Inc. Assay methods and compositions useful for measuring receptor ligand binding
DE19806581A1 (de) 1998-02-17 1999-10-21 Forschungszentrum Juelich Gmbh Sequenzen eines Ih-Ionenkanals und deren Verwendung
DE10138876B4 (de) * 2001-08-08 2008-11-06 Forschungszentrum Jülich GmbH Genetisch modifizierte zyklisch-Nukleotid-gesteuerte lonenkanäle und deren Verwendung

Also Published As

Publication number Publication date
EP1414850A2 (de) 2004-05-06
WO2003014149A2 (de) 2003-02-20
DE10138876A1 (de) 2003-03-06
DE10138876B4 (de) 2008-11-06
EP1414850B1 (de) 2013-06-19
WO2003014149A3 (de) 2003-10-09
US20060073468A1 (en) 2006-04-06
US20090104644A1 (en) 2009-04-23
US7417117B2 (en) 2008-08-26
JP4304064B2 (ja) 2009-07-29
US7951914B2 (en) 2011-05-31
JP2005507245A (ja) 2005-03-17

Similar Documents

Publication Publication Date Title
US7097969B2 (en) Non-endogenous, constitutively activated known G protein-coupled receptors
US6413764B1 (en) Human metabotropic glutamate receptors, nucleic acids encoding same and uses thereof
WO1995008627A1 (en) Human metabotropic glutamate receptor subtypes (hmr4, hmr6, hmr7) and related dna compounds
US7951914B2 (en) Genetically modified cyclic-nucleotide controlled ion channels
US6485919B1 (en) Human metabotropic glutamate receptors, nucleic acids encoding same and uses thereof
US6544753B1 (en) Galanin receptor (GALR2) binding assay
JP2001512673A (ja) Ｋｃｎｑカリウムチャンネルおよびそれの活性調節方法
US20030100059A1 (en) Novel cell-based assays for G-protein-coupled receptor-mediated activities
US20030157647A1 (en) Novel human metabotropic glutamate receptor
CA2332574A1 (en) Dna encoding orphan receptors
US20050049188A1 (en) Molecular cloning of a 7tm receptor (axor34) and screening methods thereof
EP1025226B1 (en) Dna encoding a human proton-gated ion channel and uses thereof
US6428982B1 (en) Polynucleotides encoding mouse urotensin-II Receptor (UTB-R)
US6337206B1 (en) Nucleic acid encoding mouse galanin receptor (GALR2)
US7063966B2 (en) Chimeric G protein coupled receptors
WO1997012974A2 (en) Kidney atp-dependent potassium channels
US7067277B1 (en) Chimeric G proteins and uses thereof
CA2522172A1 (en) Rhesus monkey bombesin receptor subtype-3 (brs-3), nucleotides encoding same, and uses thereof
WO2000068244A1 (en) 7tm receptor mouse apj
AU6299199A (en) Non-endogenous, constitutively activated human g protein-coupled receptors
US20020161216A1 (en) DNA encoding orphan SNORF4 receptor
WO2001087976A2 (en) Gpcr 4-helix and 5-helix bundles
CA2269192A1 (en) Novel g protein coupled receptor
WO2000068250A1 (en) 7tm receptor rat apj
AU2007202121A1 (en) Human Orphan G protein-coupled receptor hRUP7

Legal Events

Date Code Title Description
EEER Examination request
AZWI Withdrawn application

Effective date: 20130508