CA2455164C - Silencing device and method for needleless syringe - Google Patents
Silencing device and method for needleless syringe Download PDFInfo
- Publication number
- CA2455164C CA2455164C CA002455164A CA2455164A CA2455164C CA 2455164 C CA2455164 C CA 2455164C CA 002455164 A CA002455164 A CA 002455164A CA 2455164 A CA2455164 A CA 2455164A CA 2455164 C CA2455164 C CA 2455164C
- Authority
- CA
- Canada
- Prior art keywords
- gas
- silencer
- needleless syringe
- area
- bleed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title claims abstract description 19
- 230000030279 gene silencing Effects 0.000 title claims abstract description 16
- 239000002245 particle Substances 0.000 claims abstract description 178
- 230000003584 silencer Effects 0.000 claims abstract description 67
- 238000013022 venting Methods 0.000 claims abstract description 45
- 239000012528 membrane Substances 0.000 claims description 79
- 230000014759 maintenance of location Effects 0.000 claims description 66
- 238000011144 upstream manufacturing Methods 0.000 claims description 23
- 230000009172 bursting Effects 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 3
- 230000015556 catabolic process Effects 0.000 claims description 2
- 230000001419 dependent effect Effects 0.000 claims 1
- 230000002939 deleterious effect Effects 0.000 abstract description 3
- 239000007789 gas Substances 0.000 description 149
- 230000015572 biosynthetic process Effects 0.000 description 5
- 238000005755 formation reaction Methods 0.000 description 5
- 238000009826 distribution Methods 0.000 description 4
- 238000005243 fluidization Methods 0.000 description 4
- 230000001743 silencing effect Effects 0.000 description 4
- 239000001307 helium Substances 0.000 description 3
- 229910052734 helium Inorganic materials 0.000 description 3
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 230000035939 shock Effects 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 229920002799 BoPET Polymers 0.000 description 1
- 241001640034 Heteropterys Species 0.000 description 1
- 239000005041 Mylar™ Substances 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- UHZZMRAGKVHANO-UHFFFAOYSA-M chlormequat chloride Chemical compound [Cl-].C[N+](C)(C)CCCl UHZZMRAGKVHANO-UHFFFAOYSA-M 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000003116 impacting effect Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M5/3015—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Exhaust Silencers (AREA)
- Details Of Valves (AREA)
- Reciprocating Pumps (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0118266.6 | 2001-07-26 | ||
| GBGB0118266.6A GB0118266D0 (en) | 2001-07-26 | 2001-07-26 | Silencing device and method for needleless syringe |
| PCT/GB2002/003412 WO2003011380A2 (en) | 2001-07-26 | 2002-07-25 | Silencing device and method for needleless syringe |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2455164A1 CA2455164A1 (en) | 2003-02-13 |
| CA2455164C true CA2455164C (en) | 2009-10-27 |
Family
ID=9919259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002455164A Expired - Fee Related CA2455164C (en) | 2001-07-26 | 2002-07-25 | Silencing device and method for needleless syringe |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7909793B2 (https=) |
| EP (3) | EP1847286A3 (https=) |
| JP (1) | JP4299663B2 (https=) |
| AT (2) | ATE374053T1 (https=) |
| AU (1) | AU2002321403B2 (https=) |
| CA (1) | CA2455164C (https=) |
| CY (1) | CY1107088T1 (https=) |
| DE (2) | DE60209744T2 (https=) |
| DK (2) | DK1418965T3 (https=) |
| ES (2) | ES2294625T3 (https=) |
| GB (1) | GB0118266D0 (https=) |
| NZ (3) | NZ540411A (https=) |
| PT (2) | PT1637174E (https=) |
| WO (1) | WO2003011380A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8221347B2 (en) | 2004-12-01 | 2012-07-17 | Acushot, Inc. | Needle-free injector |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0100756D0 (en) | 2001-01-11 | 2001-02-21 | Powderject Res Ltd | Needleless syringe |
| US8061006B2 (en) * | 2001-07-26 | 2011-11-22 | Powderject Research Limited | Particle cassette, method and kit therefor |
| USD519633S1 (en) | 2003-11-12 | 2006-04-25 | Powderject Research Limited | Syringe |
| US7833189B2 (en) | 2005-02-11 | 2010-11-16 | Massachusetts Institute Of Technology | Controlled needle-free transport |
| US20080097407A1 (en) * | 2006-10-18 | 2008-04-24 | Michael Plishka | Luer activated device with compressible valve element |
| US7981090B2 (en) * | 2006-10-18 | 2011-07-19 | Baxter International Inc. | Luer activated device |
| US8221363B2 (en) * | 2006-10-18 | 2012-07-17 | Baxter Healthcare S.A. | Luer activated device with valve element under tension |
| US7753338B2 (en) | 2006-10-23 | 2010-07-13 | Baxter International Inc. | Luer activated device with minimal fluid displacement |
| GB0708758D0 (en) | 2007-05-04 | 2007-06-13 | Powderject Res Ltd | Particle cassettes and process thereof |
| US8398583B2 (en) | 2008-07-09 | 2013-03-19 | Massachusetts Institute Of Technology | Method and apparatus for extraction of a sample from a sample source |
| EP2434970B1 (en) | 2009-05-26 | 2016-11-30 | Zimmer, Inc. | Handheld tool for driving a bone pin into a fractured bone |
| WO2011028719A2 (en) | 2009-09-01 | 2011-03-10 | Massachusetts Institute Of Technology | Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties |
| JP5575593B2 (ja) | 2010-09-17 | 2014-08-20 | 株式会社ダイセル | 注射器 |
| JP5559647B2 (ja) | 2010-09-24 | 2014-07-23 | 株式会社ダイセル | 注射器 |
| USD699342S1 (en) * | 2011-03-09 | 2014-02-11 | Suzuken Company Limited | Injector |
| US9987067B2 (en) | 2012-07-11 | 2018-06-05 | Zimmer, Inc. | Bone fixation tool |
| US10279113B2 (en) * | 2013-05-17 | 2019-05-07 | Socpra Sciences Et Genie S.E.C. | Needleless syringe and method for delivering therapeutic particles |
| CN106163500A (zh) | 2014-02-26 | 2016-11-23 | 普乐药业有限公司 | 用于递送颗粒的装置 |
| AU2015240573B2 (en) | 2014-04-03 | 2019-03-21 | Zimmer, Inc. | Orthopedic tool for bone fixation |
| EP4706525A3 (en) | 2014-09-25 | 2026-04-22 | BT Bidco, Inc. | Electromechanical pill device with localization capabilities |
| US10729895B2 (en) * | 2014-09-30 | 2020-08-04 | The Regents Of The University Of California | Active agent delivery devices and methods of using the same |
| WO2016137665A1 (en) * | 2015-02-27 | 2016-09-01 | Zogenix, Inc. | Needle-free injectors comprising sound suppression |
| JP2017000667A (ja) | 2015-06-16 | 2017-01-05 | 国立大学法人三重大学 | 無針注射器及びそれを用いた注射対象領域へのｄｎａ導入方法 |
| KR20230042759A (ko) | 2016-09-09 | 2023-03-29 | 비오라 쎄라퓨틱스, 인크. | 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스 |
| WO2018068956A1 (en) * | 2016-10-11 | 2018-04-19 | H. Lundbeck A/S | Auto injector with automated reconstitution |
| US10966704B2 (en) | 2016-11-09 | 2021-04-06 | Biomet Sports Medicine, Llc | Methods and systems for stitching soft tissue to bone |
| US10610104B2 (en) | 2016-12-07 | 2020-04-07 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| EP3900613B1 (en) | 2017-03-31 | 2023-12-27 | Biora Therapeutics, Inc. | Localization methods for an ingestible device |
| JP7280203B2 (ja) | 2018-02-09 | 2023-05-23 | 株式会社ダイセル | 注入器及びそれを用いた注入対象の細胞核内への生体分子を含む溶液の注入方法 |
| EP3750579B1 (en) | 2018-02-09 | 2025-12-31 | Daicel Corporation | INJECTOR |
| US12083320B2 (en) | 2018-02-09 | 2024-09-10 | Daicel Corporation | Injector and method of injecting solution containing biomolecules into injection target using the same |
| CN112534274B (zh) | 2018-07-25 | 2023-10-13 | 株式会社大赛璐 | 测定系统、测定方法、注入器、以及使用该注入器向注入对象的细胞内注入包含生物分子的溶液的注入方法 |
| US20220249814A1 (en) | 2018-11-19 | 2022-08-11 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
| EP4275717A4 (en) | 2021-01-05 | 2024-06-26 | Daicel Corporation | Injector |
| CN121548441A (zh) | 2023-07-25 | 2026-02-17 | 株式会社大赛璐 | 注入器、以及使用了该注入器的空隙的形成方法、及减少对象中蓄积的细胞间液的方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR873453A (fr) * | 1941-02-19 | 1942-07-09 | Tubophane | Réservoir tubulaire pour l'emmagasinement et la distribution par projection, diffusée ou non, de matières liquides ou pulvérulentes |
| US3308818A (en) * | 1964-07-24 | 1967-03-14 | Eugene V Rutkowski | Injection cartridge |
| US5312335A (en) * | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| US5238003A (en) * | 1992-02-07 | 1993-08-24 | Baidwan Balinderjeet S | Plunger tip for blood gas syringe |
| TW404844B (en) * | 1993-04-08 | 2000-09-11 | Oxford Biosciences Ltd | Needleless syringe |
| GB9416663D0 (en) * | 1994-08-17 | 1994-10-12 | Oxford Bioscience Limited | Particle delivery |
| CA2199417C (en) | 1994-10-24 | 2008-07-08 | Brian John Bellhouse | Particle delivery |
| GB9426379D0 (en) * | 1994-12-23 | 1995-03-01 | Oxford Biosciences Ltd | Particle delivery |
| GB9502879D0 (en) * | 1995-02-14 | 1995-04-05 | Oxford Biosciences Ltd | Particle delivery |
| GB9605690D0 (en) | 1996-03-19 | 1996-05-22 | Oxford Biosciences Ltd | Particle delivery |
| US5865803A (en) * | 1997-05-19 | 1999-02-02 | Major; Miklos | Syringe device having a vented piston |
| EP0888791A1 (en) | 1997-07-04 | 1999-01-07 | PowderJect Research Limited | Syringe and drug capsule therefor |
| EP0888790A1 (en) * | 1997-07-04 | 1999-01-07 | PowderJect Research Limited | Drug particle delivery device |
| US6004287A (en) * | 1997-09-23 | 1999-12-21 | Loomis; Dale J | Biolistic apparatus for delivering substances into cells and tissues |
| US7060048B1 (en) * | 1999-04-16 | 2006-06-13 | Powerject Research Limited | Needleless syringe |
| AU765843B2 (en) * | 1999-04-16 | 2003-10-02 | Powderject Research Limited | Needleless syringe |
| GB9916800D0 (en) | 1999-07-16 | 1999-09-22 | Powderject Res Ltd | Needleless syringe |
| FR2799374B1 (fr) * | 1999-10-08 | 2001-12-07 | Cross Site Technologies | Seringue sans aiguille munie d'un systeme de declenchement par friction |
| CA2324045A1 (fr) * | 2000-10-20 | 2002-04-20 | Universite De Sherbrooke | Seringue sans aiguille pour l'injection sous-cutanee de poudres medicamenteuses |
-
2001
- 2001-07-26 GB GBGB0118266.6A patent/GB0118266D0/en not_active Ceased
-
2002
- 2002-07-25 PT PT05028151T patent/PT1637174E/pt unknown
- 2002-07-25 ES ES05028151T patent/ES2294625T3/es not_active Expired - Lifetime
- 2002-07-25 US US10/484,742 patent/US7909793B2/en active Active
- 2002-07-25 NZ NZ540411A patent/NZ540411A/en not_active IP Right Cessation
- 2002-07-25 JP JP2003516610A patent/JP4299663B2/ja not_active Expired - Fee Related
- 2002-07-25 AT AT05028151T patent/ATE374053T1/de not_active IP Right Cessation
- 2002-07-25 DK DK02755103T patent/DK1418965T3/da active
- 2002-07-25 AU AU2002321403A patent/AU2002321403B2/en not_active Ceased
- 2002-07-25 EP EP07015671A patent/EP1847286A3/en not_active Withdrawn
- 2002-07-25 CA CA002455164A patent/CA2455164C/en not_active Expired - Fee Related
- 2002-07-25 NZ NZ531227A patent/NZ531227A/en not_active IP Right Cessation
- 2002-07-25 NZ NZ551520A patent/NZ551520A/en not_active IP Right Cessation
- 2002-07-25 PT PT02755103T patent/PT1418965E/pt unknown
- 2002-07-25 EP EP02755103A patent/EP1418965B1/en not_active Expired - Lifetime
- 2002-07-25 WO PCT/GB2002/003412 patent/WO2003011380A2/en not_active Ceased
- 2002-07-25 DE DE60209744T patent/DE60209744T2/de not_active Expired - Lifetime
- 2002-07-25 EP EP05028151A patent/EP1637174B1/en not_active Expired - Lifetime
- 2002-07-25 DE DE60222709T patent/DE60222709T2/de not_active Expired - Fee Related
- 2002-07-25 DK DK05028151T patent/DK1637174T3/da active
- 2002-07-25 AT AT02755103T patent/ATE319493T1/de active
- 2002-07-25 ES ES02755103T patent/ES2260467T3/es not_active Expired - Lifetime
-
2007
- 2007-12-14 CY CY20071101585T patent/CY1107088T1/el unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8221347B2 (en) | 2004-12-01 | 2012-07-17 | Acushot, Inc. | Needle-free injector |
Also Published As
| Publication number | Publication date |
|---|---|
| US20050010168A1 (en) | 2005-01-13 |
| NZ551520A (en) | 2008-09-26 |
| GB0118266D0 (en) | 2001-09-19 |
| WO2003011380A2 (en) | 2003-02-13 |
| DK1418965T3 (da) | 2006-07-10 |
| CA2455164A1 (en) | 2003-02-13 |
| JP2004536675A (ja) | 2004-12-09 |
| NZ540411A (en) | 2007-01-26 |
| ATE374053T1 (de) | 2007-10-15 |
| ES2260467T3 (es) | 2006-11-01 |
| EP1637174A2 (en) | 2006-03-22 |
| EP1637174A3 (en) | 2006-05-03 |
| WO2003011380A3 (en) | 2003-05-30 |
| EP1847286A2 (en) | 2007-10-24 |
| ES2294625T3 (es) | 2008-04-01 |
| US7909793B2 (en) | 2011-03-22 |
| EP1418965B1 (en) | 2006-03-08 |
| EP1418965A2 (en) | 2004-05-19 |
| NZ531227A (en) | 2005-08-26 |
| DE60222709T2 (de) | 2008-06-19 |
| EP1637174B1 (en) | 2007-09-26 |
| PT1418965E (pt) | 2006-06-30 |
| DE60222709D1 (de) | 2007-11-08 |
| ATE319493T1 (de) | 2006-03-15 |
| CY1107088T1 (el) | 2012-10-24 |
| PT1637174E (pt) | 2007-11-09 |
| DK1637174T3 (da) | 2008-01-28 |
| DE60209744D1 (de) | 2006-05-04 |
| JP4299663B2 (ja) | 2009-07-22 |
| AU2002321403B2 (en) | 2007-10-04 |
| DE60209744T2 (de) | 2006-12-07 |
| EP1847286A3 (en) | 2008-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20170725 |