CA2445486A1 - Timbre d'immunisation transcutanee - Google Patents

Timbre d'immunisation transcutanee Download PDF

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Publication number
CA2445486A1
CA2445486A1 CA002445486A CA2445486A CA2445486A1 CA 2445486 A1 CA2445486 A1 CA 2445486A1 CA 002445486 A CA002445486 A CA 002445486A CA 2445486 A CA2445486 A CA 2445486A CA 2445486 A1 CA2445486 A1 CA 2445486A1
Authority
CA
Canada
Prior art keywords
antigen
protein
patch
formulation
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002445486A
Other languages
English (en)
Inventor
Gregory M. Glenn
Jianmei Yu
Mervyn L. Hamer
Jesus Miranda
Christopher L. Adams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valneva USA Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2445486A1 publication Critical patent/CA2445486A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Abstract

La présente invention concerne un timbre adhésif d'immunisation transcutanée constitué d'au moins quatre composants différents : (i) une couche dorsale; (ii) une couche adhésive sensible à la pression, adhérant à la couche dorsale; (iii) au moins une protéine, active d'un point de vue immunologique, d'une formulation immunogène appliquée sur la couche adhésive sensible à la pression, opposée à la couche dorsale et/ou incorporée dans la couche adhésive sensible à la pression, de sorte qu'au moins une protéine est en contact avec l'adhésif; et (iv) un stabilisateur qui préserve l'activité immunologique d'au moins une protéine dans des conditions ambiantes.
CA002445486A 2001-03-19 2002-03-19 Timbre d'immunisation transcutanee Abandoned CA2445486A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27649701P 2001-03-19 2001-03-19
US60/276,497 2001-03-19
PCT/US2002/008099 WO2002074325A1 (fr) 2001-03-19 2002-03-19 Timbre d'immunisation transcutanee

Publications (1)

Publication Number Publication Date
CA2445486A1 true CA2445486A1 (fr) 2002-09-26

Family

ID=23056879

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002445486A Abandoned CA2445486A1 (fr) 2001-03-19 2002-03-19 Timbre d'immunisation transcutanee

Country Status (5)

Country Link
EP (1) EP1381381A1 (fr)
JP (1) JP2004525921A (fr)
CN (1) CN1516595A (fr)
CA (1) CA2445486A1 (fr)
WO (1) WO2002074325A1 (fr)

Families Citing this family (26)

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Publication number Priority date Publication date Assignee Title
FR2822049B1 (fr) 2001-03-13 2003-08-01 Dbv Medica 1 Patch destine notamment a depister l'etat de sensibilisation d'un sujet a un allergene, procede de fabrication et utilisation
US7635488B2 (en) 2001-03-13 2009-12-22 Dbv Technologies Patches and uses thereof
JP2006503072A (ja) * 2002-10-02 2006-01-26 ノルディック ワクチン テクノロジー アクティーゼルスカブ ワクチン接種用組成物
GB0307989D0 (en) * 2003-04-07 2003-05-14 Mcewen Lab Ltd Therapeutic composition
EP1663090A4 (fr) 2003-09-12 2010-07-21 Z Medica Corp Agent hemostatique de zeolite de calcium
WO2005027834A2 (fr) 2003-09-12 2005-03-31 Z-Medica Corporation Agent hemostatique partiellement hydrate
US20060178609A1 (en) * 2005-02-09 2006-08-10 Z-Medica, Llc Devices and methods for the delivery of molecular sieve materials for the formation of blood clots
KR20070117589A (ko) 2005-02-15 2007-12-12 버지니아 커먼웰스 유니버시티 급성 지혈 및 급성 상처와 만성 궤양의 치료를 위한 광물기술
US9326995B2 (en) 2005-04-04 2016-05-03 The Regents Of The University Of California Oxides for wound healing and body repair
JP2006321720A (ja) * 2005-05-17 2006-11-30 Life Kea Giken Kk 貼付剤
TW200806315A (en) * 2006-04-26 2008-02-01 Wyeth Corp Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
US8938898B2 (en) 2006-04-27 2015-01-27 Z-Medica, Llc Devices for the identification of medical products
US7968114B2 (en) 2006-05-26 2011-06-28 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US7604819B2 (en) 2006-05-26 2009-10-20 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
WO2008105504A1 (fr) * 2007-03-01 2008-09-04 Cosmed Pharmaceutical Co., Ltd. Préparation immunitaire transdermique, son procédé de fabrication et procédé d'immunisation transdermique à l'aide de la préparation
FR2921562B1 (fr) * 2007-10-01 2012-06-15 Dbv Tech Dispositif adhesif pour application cutanee
FR2924349B1 (fr) 2007-12-03 2010-01-01 Dbv Tech Methode de desensibilitation aux allergenes
FR2924350B1 (fr) 2007-12-03 2010-08-13 Dbv Tech Procede et compositions pour la vaccination par voie cutanee
ES2711927T3 (es) * 2009-03-13 2019-05-08 Dbv Tech Método para tratar el eccema
US8858969B2 (en) 2010-09-22 2014-10-14 Z-Medica, Llc Hemostatic compositions, devices, and methods
CA3183404A1 (fr) 2012-06-22 2013-12-27 Teleflex Life Sciences Limited Dispositifs hemostatiques
JP6323975B2 (ja) * 2012-06-22 2018-05-16 凸版印刷株式会社 針状体の製造方法
CN103356511B (zh) * 2013-06-20 2015-03-25 海南光宇生物科技有限公司 一种蛋白药物透皮给药药贴
EP3146964A4 (fr) * 2014-05-20 2018-01-10 Alcare Co., Ltd. Composition d'agent adhésif pour la peau et matériau de timbre transdermique
ITUA20164065A1 (it) * 2016-06-01 2017-12-01 Probiotical Spa Composizioni in gel per applicazioni topiche a base di batteri, preparazione delle stesse e loro usi.
WO2018220926A1 (fr) * 2017-05-30 2018-12-06 Ｎｉｓｓｈａ株式会社 Timbre à micro-aiguilles et matériau d'emballage pour celui-ci

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260066A (en) * 1992-01-16 1993-11-09 Srchem Incorporated Cryogel bandage containing therapeutic agent
US5756117A (en) * 1992-04-08 1998-05-26 International Medical Asscociates, Inc. Multidose transdermal drug delivery system
CA2183083C (fr) * 1994-03-07 2006-01-03 Charles D. Ebert Systeme adhesif pour l'administration transdermique d'un medicament
US5536263A (en) * 1994-03-30 1996-07-16 Lectec Corporation Non-occulusive adhesive patch for applying medication to the skin
IL113034A (en) * 1994-04-05 2000-02-17 Astra Ab Topical dressing
DE4416927C1 (de) * 1994-05-13 1995-08-31 Lohmann Therapie Syst Lts Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung
US5505958A (en) * 1994-10-31 1996-04-09 Algos Pharmaceutical Corporation Transdermal drug delivery device and method for its manufacture
EP0746311B1 (fr) * 1994-12-24 2001-07-11 Pacific Corporation Timbres medicaux pour administration percutanee
US5780050A (en) * 1995-07-20 1998-07-14 Theratech, Inc. Drug delivery compositions for improved stability of steroids
US6033684A (en) * 1996-08-28 2000-03-07 Jonor, Inc. Compositions and methods for wound management
US5910306A (en) * 1996-11-14 1999-06-08 The United States Of America As Represented By The Secretary Of The Army Transdermal delivery system for antigen
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US6348450B1 (en) * 1997-08-13 2002-02-19 The Uab Research Foundation Noninvasive genetic immunization, expression products therefrom and uses thereof
AU3311599A (en) * 1998-02-25 1999-09-15 Iomai Corporation Use of skin penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response induced by adp-ribosylating exotoxin
SE9801898L (sv) * 1998-05-28 1999-07-05 Moelnlycke Health Care Ab Sårförband eller fixeringstejp för hud innefattande ett plastfilmsskikt belagt med en klibbig elastomer innehållande partikelformiga förankringselement
WO2000033812A2 (fr) * 1998-12-07 2000-06-15 Elan Corporation, Plc Timbre transdermique pour administrer des medicaments liquides volatiles
WO2000061184A2 (fr) * 1999-04-08 2000-10-19 Glenn Gregory M Formulation seche pour immunisation transcutanee
US6348212B2 (en) * 1999-05-18 2002-02-19 Lectec Corporation Treating traumatic burns or blisters of the skin
WO2000074714A2 (fr) * 1999-06-03 2000-12-14 Glenn Gregory M Indicateurs de controle de la technique d'immunisation transcutanee

Also Published As

Publication number Publication date
CN1516595A (zh) 2004-07-28
WO2002074325A1 (fr) 2002-09-26
EP1381381A1 (fr) 2004-01-21
JP2004525921A (ja) 2004-08-26

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Legal Events

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FZDE Dead