CA2436091A1 - Neutralizing human monoclonal antibodies against hiv-1, their production and uses - Google Patents
Neutralizing human monoclonal antibodies against hiv-1, their production and uses Download PDFInfo
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- CA2436091A1 CA2436091A1 CA002436091A CA2436091A CA2436091A1 CA 2436091 A1 CA2436091 A1 CA 2436091A1 CA 002436091 A CA002436091 A CA 002436091A CA 2436091 A CA2436091 A CA 2436091A CA 2436091 A1 CA2436091 A1 CA 2436091A1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- AIDS & HIV (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26439801P | 2001-01-26 | 2001-01-26 | |
| US60/264,398 | 2001-01-26 | ||
| US26610601P | 2001-02-02 | 2001-02-02 | |
| US60/266,106 | 2001-02-02 | ||
| US26598401P | 2001-02-03 | 2001-02-03 | |
| US60/265,984 | 2001-02-03 | ||
| US27046601P | 2001-02-21 | 2001-02-21 | |
| US60/270,466 | 2001-02-21 | ||
| PCT/US2002/002171 WO2002059154A2 (en) | 2001-01-26 | 2002-01-25 | Neutralizing human monoclonal antibodies against hiv-1, their production and uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2436091A1 true CA2436091A1 (en) | 2002-08-01 |
Family
ID=27500822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002436091A Abandoned CA2436091A1 (en) | 2001-01-26 | 2002-01-25 | Neutralizing human monoclonal antibodies against hiv-1, their production and uses |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20050058983A1 (enExample) |
| EP (1) | EP1373318A2 (enExample) |
| JP (1) | JP2005510201A (enExample) |
| CA (1) | CA2436091A1 (enExample) |
| WO (1) | WO2002059154A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1431306A1 (en) * | 2002-12-19 | 2004-06-23 | Creabilis Therapeutics s.r.l. | A mechanism for hiv-1 entry into host cells and peptides inhibiting this mechanism |
| WO2004024173A2 (en) * | 2002-09-13 | 2004-03-25 | Creabilis Therapeutics S.P.A. | A mechanism for hiv-1 entry into host cells and peptides inhibiting this mechanism |
| US6821744B2 (en) * | 2002-10-29 | 2004-11-23 | Roche Diagnostics Operations, Inc. | Method, assay, and kit for quantifying HIV protease inhibitors |
| AU2003288057A1 (en) * | 2002-11-14 | 2004-06-03 | Novartis Ag | Antimicrobial activity of antibodies producing reactive oxygen species |
| WO2004074516A2 (ja) * | 2003-02-20 | 2004-09-02 | Chemo Sero Therapeut Res Inst | モノクローナル抗体製剤の奏効性を向上させる方法 |
| FR2861255B1 (fr) | 2003-10-24 | 2006-02-17 | Centre Nat Rech Scient | Mammifere non-humain transgenique pour la region constante de la chaine lourde des immunoglobulines humaines de classe a et ses applications. |
| US20060205070A1 (en) * | 2004-01-13 | 2006-09-14 | The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services | HIV TEV compositions and methods of use |
| WO2006002382A2 (en) * | 2004-06-24 | 2006-01-05 | The Scripps Research Institute | Arrays with cleavable linkers |
| EP2349333A4 (en) | 2008-10-30 | 2012-08-29 | Dana Farber Cancer Inst Inc | Mimotopes of hiv env |
| EP2900693A4 (en) * | 2012-09-26 | 2016-05-11 | Univ Duke | ADCC-mediating antibodies, combinations and uses thereof |
| HUE051577T2 (hu) | 2012-10-18 | 2021-03-01 | Univ Rockefeller | Széleskörû semlegesítést biztosító anti-HIV ellenanyagok |
| US9101597B2 (en) * | 2013-03-14 | 2015-08-11 | The Administration Of The Tulane Educational Fund | Immunoprotective primary mesenchymal stem cells and methods |
| CN107936116A (zh) * | 2018-01-16 | 2018-04-20 | 河南牧业经济学院 | 高效价抗csfv单克隆抗体的制备方法 |
| CN113813375B (zh) * | 2020-06-19 | 2023-06-16 | 杭州星鳌生物科技有限公司 | 一种新型抗新冠病毒复合物的组成及其在防治冠状病毒感染疾病药物中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5266478A (en) * | 1987-05-29 | 1993-11-30 | Tanox Biosystems, Inc. | Antibodies which target a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120 |
| US5643756A (en) * | 1992-08-28 | 1997-07-01 | The Public Health Research Institute Of The City Of New York, Inc. | Fusion glycoproteins |
| WO1995024904A1 (en) * | 1994-03-16 | 1995-09-21 | Tanox Biosystems, Inc. | Synergistic inhibition of hiv-1 infection using a nucleoside reverse transcriptase inhibitor and anti-hiv-1 antibodies |
| EP0823941A4 (en) * | 1995-04-28 | 2001-09-19 | Abgenix Inc | HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES |
| US6815201B2 (en) * | 1997-09-08 | 2004-11-09 | The Public Health Research Institute Of The City Of New York, Inc. | HIV-1 gp120 V1/V2 domain epitopes capable of generating neutralizing antibodies |
-
2002
- 2002-01-25 EP EP02707565A patent/EP1373318A2/en not_active Withdrawn
- 2002-01-25 CA CA002436091A patent/CA2436091A1/en not_active Abandoned
- 2002-01-25 WO PCT/US2002/002171 patent/WO2002059154A2/en not_active Ceased
- 2002-01-25 JP JP2002559456A patent/JP2005510201A/ja active Pending
-
2003
- 2003-07-25 US US10/628,004 patent/US20050058983A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1373318A2 (en) | 2004-01-02 |
| WO2002059154A3 (en) | 2003-10-09 |
| US20050058983A1 (en) | 2005-03-17 |
| WO2002059154A2 (en) | 2002-08-01 |
| JP2005510201A (ja) | 2005-04-21 |
| WO2002059154A9 (en) | 2003-08-14 |
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