CA2435876A1 - Traitement de troubles sexuels et de maladie cardio-vasculaire avec des enantiomeres quinolinone - Google Patents

Traitement de troubles sexuels et de maladie cardio-vasculaire avec des enantiomeres quinolinone Download PDF

Info

Publication number
CA2435876A1
CA2435876A1 CA002435876A CA2435876A CA2435876A1 CA 2435876 A1 CA2435876 A1 CA 2435876A1 CA 002435876 A CA002435876 A CA 002435876A CA 2435876 A CA2435876 A CA 2435876A CA 2435876 A1 CA2435876 A1 CA 2435876A1
Authority
CA
Canada
Prior art keywords
flosequinan
enantiomer
enantiomers
patient
symptoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002435876A
Other languages
English (en)
Inventor
Neal R. Cutler
John Sramek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RT Alamo Ventures I LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/771,104 external-priority patent/US6562838B2/en
Priority claimed from US09/770,704 external-priority patent/US20020147217A1/en
Application filed by Individual filed Critical Individual
Publication of CA2435876A1 publication Critical patent/CA2435876A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Quinoline Compounds (AREA)

Abstract

La présente invention concerne des techniques de traitement de groupes de patients spécifiques soignés pour des troubles sexuels. Les techniques de cette invention comprennent l'utilisation d'énantiomères de floséquinan et des compositions pharmaceutiques comprenant des énantiomères de floséquinan, chez des patients exempts de maladies cardiaques, qui n'ont pas été traité avec un médicament hypotenseur et/ou à qui on n'a pas donné de nitrites ou de nitrates organiques. Ces énantiomères de floséquinan et les compositions comprenant ces énantiomères de floséquinan sont administrés aux patients par voie nasale, orale et/ou par inhalation. Cette invention concerne aussi des compositions et des techniques de traitement de maladie cardio-vasculaire. Dans un mode de réalisation préféré, cette invention concerne l'utilisation d'énantiomères de floséquinan (et de préparations comprenant du floséquinan) chez des sujets qui ne sont pas simultanément traités avec des nitrites ou des nitrates.
CA002435876A 2001-01-26 2002-01-24 Traitement de troubles sexuels et de maladie cardio-vasculaire avec des enantiomeres quinolinone Abandoned CA2435876A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/770,704 2001-01-26
US09/771,104 US6562838B2 (en) 2001-01-26 2001-01-26 Treatment of cardiovascular disease with quinolinone enantiomers
US09/770,704 US20020147217A1 (en) 2001-01-26 2001-01-26 The treatment of sexual dysfunction with enantiomers
US09/771,104 2001-01-26
PCT/US2002/002357 WO2002058703A2 (fr) 2001-01-26 2002-01-24 Traitement de troubles sexuels et de maladie cardio-vasculaire avec des enantiomeres quinolinone

Publications (1)

Publication Number Publication Date
CA2435876A1 true CA2435876A1 (fr) 2002-08-01

Family

ID=27118348

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002435876A Abandoned CA2435876A1 (fr) 2001-01-26 2002-01-24 Traitement de troubles sexuels et de maladie cardio-vasculaire avec des enantiomeres quinolinone

Country Status (4)

Country Link
EP (1) EP1355647A2 (fr)
JP (1) JP2005503995A (fr)
CA (1) CA2435876A1 (fr)
WO (1) WO2002058703A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040014761A1 (en) * 1997-10-28 2004-01-22 Place Virgil A. Treatment of female sexual dysfunction with phosphodiesterase inhibitors
US6649764B2 (en) * 2001-10-25 2003-11-18 R. T. Alamo Ventures I, Llc Stereospecific enrichment of heterocyclic enantiomers

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9908716A (pt) * 1998-05-01 2000-11-21 Neal R Cutler Tratamento de disfunção sexual em certos grupos de pacientes
CA2339484A1 (fr) * 1998-08-03 2000-02-17 Robert A. O'brien Utilisation de pyridinones pour traiter les dysfonctionnements sexuels

Also Published As

Publication number Publication date
JP2005503995A (ja) 2005-02-10
WO2002058703A3 (fr) 2003-08-14
WO2002058703A2 (fr) 2002-08-01
EP1355647A2 (fr) 2003-10-29

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead