CA2432525C - Streptococcus pyogenes antigens and corresponding dna fragments - Google Patents

Streptococcus pyogenes antigens and corresponding dna fragments Download PDF

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Publication number
CA2432525C
CA2432525C CA2432525A CA2432525A CA2432525C CA 2432525 C CA2432525 C CA 2432525C CA 2432525 A CA2432525 A CA 2432525A CA 2432525 A CA2432525 A CA 2432525A CA 2432525 C CA2432525 C CA 2432525C
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Canada
Prior art keywords
polypeptide
ala
gly
lys
val
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2432525A
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English (en)
French (fr)
Other versions
CA2432525A1 (en
Inventor
Denis Martin
Josee Hamel
Bernard R. Brodeur
Stephane Rioux
Patrick Rheault
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Individual
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Individual
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Priority to CA2789252A priority Critical patent/CA2789252C/en
Publication of CA2432525A1 publication Critical patent/CA2432525A1/en
Application granted granted Critical
Publication of CA2432525C publication Critical patent/CA2432525C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0208Specific bacteria not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56944Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/315Assays involving biological materials from specific organisms or of a specific nature from bacteria from Streptococcus (G), e.g. Enterococci
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
CA2432525A 2000-12-21 2001-12-21 Streptococcus pyogenes antigens and corresponding dna fragments Expired - Fee Related CA2432525C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2789252A CA2789252C (en) 2000-12-21 2001-12-21 Streptococcus pyogenes antigens and corresponding dna fragments

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25694000P 2000-12-21 2000-12-21
US60/256,940 2000-12-21
PCT/CA2001/001853 WO2002050107A2 (en) 2000-12-21 2001-12-21 Streptococcus pyogenes antigens and corresponding dna fragments

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2789252A Division CA2789252C (en) 2000-12-21 2001-12-21 Streptococcus pyogenes antigens and corresponding dna fragments

Publications (2)

Publication Number Publication Date
CA2432525A1 CA2432525A1 (en) 2002-06-27
CA2432525C true CA2432525C (en) 2012-11-27

Family

ID=22974225

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2432525A Expired - Fee Related CA2432525C (en) 2000-12-21 2001-12-21 Streptococcus pyogenes antigens and corresponding dna fragments
CA2789252A Expired - Fee Related CA2789252C (en) 2000-12-21 2001-12-21 Streptococcus pyogenes antigens and corresponding dna fragments

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2789252A Expired - Fee Related CA2789252C (en) 2000-12-21 2001-12-21 Streptococcus pyogenes antigens and corresponding dna fragments

Country Status (12)

Country Link
US (5) US7595057B2 (https=)
EP (1) EP1343895B1 (https=)
JP (1) JP4080876B2 (https=)
AT (1) ATE398677T1 (https=)
AU (2) AU2002216863B8 (https=)
BE (1) BE2021C506I2 (https=)
BR (1) BR0116704A (https=)
CA (2) CA2432525C (https=)
DE (1) DE60134494D1 (https=)
ES (1) ES2307564T3 (https=)
FR (1) FR21C1005I2 (https=)
WO (1) WO2002050107A2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002216863B8 (en) * 2000-12-21 2008-03-20 Id Biomedical Corporation Streptococcus pyogenes antigens and corresponding DNA fragments
GB0130228D0 (en) 2001-12-18 2002-02-06 Hansa Medica Ab Protein
WO2005017093A2 (en) * 2003-08-15 2005-02-24 Id Biomedical Corporation Polypeptides of streptococcus pyogenes
GB201502305D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
GB201502306D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
EP4687953A2 (en) * 2023-03-29 2026-02-11 Cyrus Biotechnology, Inc. Ides variant proteins and methods of using the same

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5854416A (en) * 1991-11-14 1998-12-29 The United States Of America As Represented By The Department Of Health And Human Services Streptococcus pneumoniae 37-KDA surface adhesin a protein and nucleic acids coding therefor
US6287574B1 (en) 1995-03-17 2001-09-11 Biochem Pharma Inc. Proteinase K resistant surface protein of neisseria meningitidis
CA2321106C (en) * 1998-02-20 2013-07-23 Biochem Pharma Inc. Group b streptococcus antigens
GB9807890D0 (en) * 1998-04-09 1998-06-10 Actinova Ltd Peptides
WO2000006736A2 (en) 1998-07-27 2000-02-10 Microbial Technics Limited Nucleic acids and proteins from group b streptococcus
ATE361365T1 (de) 1998-07-27 2007-05-15 Sanofi Pasteur Ltd Streptococcus pneumoniae proteine und nukleinsäuren
US7128918B1 (en) * 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
GB9828880D0 (en) * 1998-12-31 1999-02-17 Actinova Ltd Protein
US7074415B2 (en) * 2000-06-20 2006-07-11 Id Biomedical Corporation Streptococcus antigens
JP4718099B2 (ja) * 2000-07-06 2011-07-06 アイディー バイオメディカル コーポレイション ストレプトコッカス・パイオジェンス抗原
JP4102186B2 (ja) * 2000-10-13 2008-06-18 アイディー バイオメディカル コーポレイション グループbストレプトコッカスのbvh−a2及びbvh−a3抗原
CA2881568C (en) * 2000-10-27 2019-09-24 Novartis Vaccines And Diagnostics, Inc. Nucleic acids and proteins from streptococcus groups a & b
AU2002216863B8 (en) * 2000-12-21 2008-03-20 Id Biomedical Corporation Streptococcus pyogenes antigens and corresponding DNA fragments
BRPI0207447B1 (pt) * 2001-02-21 2015-09-22 Id Biomedical Corp polipeptídeo recombinante isolado, seu uso e processo de produção, vetor de expressão, célula hospedeira microbiana transgênica, composição farmacêutica, uso da dita composição, métodos de detecção e kit
BR0208874A (pt) * 2001-04-13 2004-06-22 Wyeth Corp Proteìnas superficiais de streptococcus pyogenes
BR0210875A (pt) * 2001-07-06 2004-06-22 Shire Biochem Inc Antìgenos de streptococcus do grupo b e fragmentos de dna correspondentes
GB0130228D0 (en) * 2001-12-18 2002-02-06 Hansa Medica Ab Protein
EP1456231A2 (en) * 2001-12-20 2004-09-15 Shire Biochem Inc. Streptococcus antigens
AU2003246495A1 (en) * 2002-07-15 2004-02-02 Id Biomedical Corporation Polypeptide of streptococcus pyogenes
WO2005017093A2 (en) * 2003-08-15 2005-02-24 Id Biomedical Corporation Polypeptides of streptococcus pyogenes
US7838010B2 (en) * 2004-10-08 2010-11-23 Novartis Vaccines And Diagnostics S.R.L. Immunogenic and therapeutic compositions for Streptococcus pyogenes
PL1901773T3 (pl) * 2005-06-09 2012-09-28 Hansa Medical Ab Zastosowanie proteinazy IDES (Z S. Pyogenes) do leczenia chorób autoimmunologicznych oraz odrzutów przeszczepu
US8309096B2 (en) * 2007-01-15 2012-11-13 Glaxosmithkline Biologicals S.A. Fusion protein
DK2190984T3 (da) * 2007-09-14 2013-12-02 Genovis Ab Fremgangsmåder og kits til oprensning og påvisning af glycosyleret IgG
GB201003920D0 (en) * 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Method of treatment
GB201115841D0 (en) * 2011-09-13 2011-10-26 Genovis Ab Protein and method
GB201316744D0 (en) * 2013-09-20 2013-11-06 Genovis Ab Method
GB201416849D0 (en) * 2014-09-24 2014-11-05 Genovis Ab Method

Also Published As

Publication number Publication date
JP2004524014A (ja) 2004-08-12
US20100119507A1 (en) 2010-05-13
FR21C1005I1 (https=) 2021-03-26
EP1343895A2 (en) 2003-09-17
US8821895B2 (en) 2014-09-02
US20040097706A1 (en) 2004-05-20
AU1686302A (en) 2002-07-01
US20150017684A1 (en) 2015-01-15
JP4080876B2 (ja) 2008-04-23
US20160326221A1 (en) 2016-11-10
WO2002050107A3 (en) 2003-04-10
AU2002216863B2 (en) 2008-02-28
EP1343895B1 (en) 2008-06-18
FR21C1005I2 (fr) 2022-01-14
BR0116704A (pt) 2003-12-23
US20130136760A1 (en) 2013-05-30
AU2002216863B8 (en) 2008-03-20
BE2021C506I2 (https=) 2021-05-31
CA2789252A1 (en) 2002-06-27
US7595057B2 (en) 2009-09-29
ATE398677T1 (de) 2008-07-15
US8298551B2 (en) 2012-10-30
DE60134494D1 (de) 2008-07-31
US9340586B2 (en) 2016-05-17
WO2002050107A2 (en) 2002-06-27
CA2789252C (en) 2016-11-15
ES2307564T9 (es) 2021-04-26
ES2307564T3 (es) 2008-12-01
CA2432525A1 (en) 2002-06-27

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Effective date: 20191223