CA2429803A1 - Neutral and anionic colloidal particles for gene delivery - Google Patents

Neutral and anionic colloidal particles for gene delivery Download PDF

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Publication number
CA2429803A1
CA2429803A1 CA002429803A CA2429803A CA2429803A1 CA 2429803 A1 CA2429803 A1 CA 2429803A1 CA 002429803 A CA002429803 A CA 002429803A CA 2429803 A CA2429803 A CA 2429803A CA 2429803 A1 CA2429803 A1 CA 2429803A1
Authority
CA
Canada
Prior art keywords
cationic
dna
dna complex
complex
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002429803A
Other languages
English (en)
French (fr)
Inventor
Hans Hofland
Donald Lamons
Xiao-Ying Meng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centelion SAS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0105346A external-priority patent/GB0105346D0/en
Application filed by Individual filed Critical Individual
Publication of CA2429803A1 publication Critical patent/CA2429803A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)
CA002429803A 2000-11-29 2001-11-27 Neutral and anionic colloidal particles for gene delivery Abandoned CA2429803A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US25382700P 2000-11-29 2000-11-29
US60/253,827 2000-11-29
GB0105346.1 2001-03-05
GB0105346A GB0105346D0 (en) 2000-11-29 2001-03-05 Neutral and anionic colloidal particles for gene delivery
PCT/EP2001/013800 WO2002043769A2 (en) 2000-11-29 2001-11-27 Neutral and anionic colloidal particles for gene delivery

Publications (1)

Publication Number Publication Date
CA2429803A1 true CA2429803A1 (en) 2002-06-06

Family

ID=26245779

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002429803A Abandoned CA2429803A1 (en) 2000-11-29 2001-11-27 Neutral and anionic colloidal particles for gene delivery

Country Status (6)

Country Link
EP (1) EP1370295A2 (ja)
JP (1) JP2004520288A (ja)
AU (1) AU2073002A (ja)
CA (1) CA2429803A1 (ja)
IL (1) IL155699A0 (ja)
WO (1) WO2002043769A2 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05010499A (es) * 2003-03-31 2006-05-25 Johnson & Johnson Particulas lipidicas que tienen un revestimiento lipidico asimetrico y metodo de preparacion de las mismas.
US8969543B2 (en) 2003-04-03 2015-03-03 Bioneer Corporation SiRNA-hydrophilic polymer conjugates for intracellular delivery of siRNA and method thereof
WO2004087931A1 (en) * 2003-04-03 2004-10-14 Korea Advanced Institute Of Science And Technology Conjugate for gene transfer comprising oligonucleotide and hydrophilic polymer, polyelectrolyte complex micelles formed from the conjugate, and methods for preparation thereof
WO2008005479A2 (en) * 2006-07-06 2008-01-10 University Of Wyoming Charge reversible polymers

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT941066E (pt) * 1996-08-26 2004-03-31 Transgene Sa Complexos de lipido cationico - acido nucleico
FR2763943B1 (fr) * 1997-05-28 1999-07-09 Rhone Poulenc Rorer Sa Composes, leur preparation et leur utilisation pour le transfert d'acides nucleiques dans les cellules

Also Published As

Publication number Publication date
JP2004520288A (ja) 2004-07-08
EP1370295A2 (en) 2003-12-17
AU2073002A (en) 2002-06-11
WO2002043769A3 (en) 2003-10-09
IL155699A0 (en) 2003-11-23
WO2002043769A2 (en) 2002-06-06

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued