CA2418720A1 - Caspase inhibitors and uses thereof - Google Patents

Caspase inhibitors and uses thereof Download PDF

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Publication number
CA2418720A1
CA2418720A1 CA002418720A CA2418720A CA2418720A1 CA 2418720 A1 CA2418720 A1 CA 2418720A1 CA 002418720 A CA002418720 A CA 002418720A CA 2418720 A CA2418720 A CA 2418720A CA 2418720 A1 CA2418720 A1 CA 2418720A1
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Prior art keywords
group
optionally substituted
disease
ring
compound
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Abandoned
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CA002418720A
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English (en)
French (fr)
Inventor
Jean-Damien Charrier
Ronald Knegtel
Michael Mortimore
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Vertex Pharmaceuticals Inc
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Individual
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    • C07ORGANIC CHEMISTRY
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    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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CA002418720A 2000-09-13 2001-09-12 Caspase inhibitors and uses thereof Abandoned CA2418720A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23257300P 2000-09-13 2000-09-13
US60/232,573 2000-09-13
PCT/US2001/028450 WO2002022611A2 (en) 2000-09-13 2001-09-12 Caspase inhibitors and uses thereof

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CA2418720A1 true CA2418720A1 (en) 2002-03-21

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CA002418720A Abandoned CA2418720A1 (en) 2000-09-13 2001-09-12 Caspase inhibitors and uses thereof

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US (1) US6800619B2 (enExample)
EP (1) EP1317454B1 (enExample)
JP (2) JP2004509120A (enExample)
AT (1) ATE510837T1 (enExample)
AU (1) AU2001290795A1 (enExample)
CA (1) CA2418720A1 (enExample)
PE (1) PE20020500A1 (enExample)
WO (1) WO2002022611A2 (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020058636A1 (en) * 1994-09-21 2002-05-16 Geoffrey P. Symonds Ribozymes targeting the retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs
PE20011350A1 (es) 2000-05-19 2002-01-15 Vertex Pharma PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
PE20020500A1 (es) * 2000-09-13 2002-06-25 Vertex Pharma Derivados de piperidina, tetrahidroquinolina, tetrahidroisoquinolina como inhibidores de caspasas
FR2815541B1 (fr) * 2000-10-24 2008-02-29 Lipha Utilisation d'inhibiteurs de l'apoptose des pericytes pour le traitement et/ou la prevention de la retinopathie diabetique
MXPA03009647A (es) * 2001-04-19 2004-01-29 Vertex Pharma Heterociclildicarbamidas como inhibidores de caspasa.
JP4428926B2 (ja) * 2001-05-23 2010-03-10 バーテックス ファーマシューティカルズ インコーポレイテッド カスパーゼインヒビターおよびそれらの使用
CA2453531A1 (en) 2001-07-10 2003-01-23 Johnson & Johnson Research Pty Limited Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells
WO2003068242A1 (en) 2002-02-11 2003-08-21 Vertex Pharmaceuticals Incorporated Phospholipids as caspase inhibitor prodrugs
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WO2002022611A2 (en) 2002-03-21
WO2002022611A3 (en) 2002-10-31
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US20020058630A1 (en) 2002-05-16

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