CA2407886A1 - Production of adenine nucleotide translocator (ant), novel ant ligands and screening assays therefor - Google Patents

Production of adenine nucleotide translocator (ant), novel ant ligands and screening assays therefor Download PDF

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Publication number
CA2407886A1
CA2407886A1 CA002407886A CA2407886A CA2407886A1 CA 2407886 A1 CA2407886 A1 CA 2407886A1 CA 002407886 A CA002407886 A CA 002407886A CA 2407886 A CA2407886 A CA 2407886A CA 2407886 A1 CA2407886 A1 CA 2407886A1
Authority
CA
Canada
Prior art keywords
ant
polypeptide
adenine nucleotide
cell
nucleotide translocator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002407886A
Other languages
English (en)
French (fr)
Inventor
Christen M. Anderson
Robert E. Davis
William Clevenger
Sandra Eileen Wiley
Scott W. Miller
Tomas R. Szabo
Soumitra S. Ghosh
Walter H. Moos
Yazhong Pei
Amy K. Carroll
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Migenix Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2407886A1 publication Critical patent/CA2407886A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002407886A 2000-05-11 2001-05-11 Production of adenine nucleotide translocator (ant), novel ant ligands and screening assays therefor Abandoned CA2407886A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56932700A 2000-05-11 2000-05-11
US09/569,327 2000-05-11
PCT/US2001/015416 WO2001085944A2 (en) 2000-05-11 2001-05-11 Production of adenine nucleotide translocator (ant), novel ant ligands and screening assays therefor

Publications (1)

Publication Number Publication Date
CA2407886A1 true CA2407886A1 (en) 2001-11-15

Family

ID=24274963

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002407886A Abandoned CA2407886A1 (en) 2000-05-11 2001-05-11 Production of adenine nucleotide translocator (ant), novel ant ligands and screening assays therefor

Country Status (5)

Country Link
EP (2) EP1283884A2 (enExample)
JP (1) JP2003532420A (enExample)
AU (1) AU2001261518A1 (enExample)
CA (1) CA2407886A1 (enExample)
WO (1) WO2001085944A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0328048D0 (en) * 2003-12-04 2004-01-07 Univ Sheffield Gene screen
CA2725220C (en) * 2008-05-30 2018-07-31 Mitologics Pyrimidinones and pyrimidines derivates as ant-ligands molecules and biological applications
KR101505239B1 (ko) * 2008-07-15 2015-03-23 대련진오약업유한회사(따리안 지아 파마슈티컬 컴패니, 리미티드) 심근 펩타이드, 이의 제조방법 및 용도
CN104678031B (zh) * 2015-01-23 2016-05-04 四川省中医药科学院 高效液相色谱法检测苍术苷和/或羧基苍术苷的方法
CN116593431B (zh) * 2023-04-09 2025-11-07 湖南科技大学三亚研究院 一种基于亲和传感器法的米酵菌酸毒素便携式检测装置及检测方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3484078D1 (de) * 1983-06-27 1991-03-14 Genentech Inc Uebertragbare induzierbare kontrollsysteme, diese enthaltende expressionsvektoren, mit diesen transformierte mikroorganismen und ihre verwendung bei der expression von exogenem protein.
EP0477961B1 (en) * 1990-09-26 1996-09-11 Sumitomo Chemical Company, Limited Mitochondrial P450
US5656495A (en) * 1995-01-20 1997-08-12 Bristol-Myers Squibb Company Expression vector for human topoisomerase I
US5859215A (en) * 1995-10-25 1999-01-12 Wallac Oy Biospecific binding reactants labelled with luminescent lanthanide chelates and their use
WO1998019714A1 (en) * 1996-11-01 1998-05-14 Emory University Mouse lacking heart-muscle adenine nucleotide translocator protein and methods
DE19653498C1 (de) * 1996-12-20 1998-07-23 Wolf M Prof Dr Bertling Klonierungsvektor-System mit Fusionssequenz
US20030044776A1 (en) * 1998-09-25 2003-03-06 James A. Dykens Compositions and methods for identifying agents that alter mitochondrial permeability transition pores
WO2000026370A2 (en) * 1998-11-03 2000-05-11 Mitokor Adenine nucleotide translocator (ant) fusion proteins and uses thereof
CA2377684A1 (en) * 1999-06-30 2001-01-11 Martin Dene Brand Screening method
US6562563B1 (en) * 1999-11-03 2003-05-13 Mitokor Compositions and mehtods for determining interactions of mitochondrial components, and for identifying agents that alter such interactions

Also Published As

Publication number Publication date
AU2001261518A1 (en) 2001-11-20
WO2001085944A2 (en) 2001-11-15
WO2001085944A3 (en) 2002-08-29
JP2003532420A (ja) 2003-11-05
EP1783221A1 (en) 2007-05-09
EP1283884A2 (en) 2003-02-19

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Legal Events

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EEER Examination request
FZDE Dead