CA2407272A1 - Procede et composition permettant d'analyser un polymere glucidique - Google Patents
Procede et composition permettant d'analyser un polymere glucidique Download PDFInfo
- Publication number
- CA2407272A1 CA2407272A1 CA002407272A CA2407272A CA2407272A1 CA 2407272 A1 CA2407272 A1 CA 2407272A1 CA 002407272 A CA002407272 A CA 002407272A CA 2407272 A CA2407272 A CA 2407272A CA 2407272 A1 CA2407272 A1 CA 2407272A1
- Authority
- CA
- Canada
- Prior art keywords
- saccharide
- binding agent
- binding
- carbohydrate polymer
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/415—Assays involving biological materials from specific organisms or of a specific nature from plants
- G01N2333/42—Lectins, e.g. concanavalin, phytohaemagglutinin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/02—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates involving antibodies to sugar part of glycoproteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Abstract
L'invention concerne un procédé permettant de caractériser un polymère glucidique par identification d'au moins deux agents de liaison se liant au polymère glucidique. De préférence, la liaison est déterminée par mise en contact du polymère glucidique avec un substrat contenant plusieurs premiers agents de liaison à la saccharide fixés à des emplacements prédéterminés sur le substrat. Le polymère glucidique peut ainsi entrer en contact avec le substrat dans des conditions permettant la formation d'un premier complexe entre ledit premier agent de liaison et le polymère glucidique. Un second agent de liaison à la saccharide, comprenant, de préférence, un traceur, est également mis en contact avec le polymère glucidique dans des conditions permettant la formation d'un second complexe entre le second agent de liaison et le premier complexe. L'identification du premier agent de liaison et du second agent de liaison permet de caractériser le polysaccharide.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IL2000/000256 WO2000068688A1 (fr) | 1999-05-06 | 2000-05-04 | Structure polysaccharidique et determination de la sequence |
ILPCT/IL00/00256 | 2000-05-04 | ||
PCT/US2000/030402 WO2001084147A1 (fr) | 2000-05-04 | 2000-11-03 | Procede et composition permettant d"analyser un polymere glucidique |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2407272A1 true CA2407272A1 (fr) | 2001-11-08 |
Family
ID=11042969
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002407272A Abandoned CA2407272A1 (fr) | 2000-05-04 | 2000-11-03 | Procede et composition permettant d'analyser un polymere glucidique |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1281082A1 (fr) |
JP (1) | JP2004506874A (fr) |
AU (1) | AU2001217569A1 (fr) |
CA (1) | CA2407272A1 (fr) |
WO (1) | WO2001084147A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL129835A (en) | 1999-05-06 | 2008-03-20 | Ofer Markman | Polysaccharide sequencing and structure determination |
JP4176467B2 (ja) * | 2000-11-03 | 2008-11-05 | プロコグニア (イスラエル) リミテッド | 炭水化物ポリマーの比較分析のための方法 |
US7079955B2 (en) | 2000-11-03 | 2006-07-18 | Procognia, Ltd. | System and method for integrated analysis of data for characterizing carbohydrate polymers |
US20050158146A1 (en) * | 2001-10-16 | 2005-07-21 | Amor Yehudit | Method of preparing purified biologically active oligosaccharide libraries |
DE10249608A1 (de) * | 2002-10-18 | 2004-05-06 | Gkss-Forschungszentrum Geesthacht Gmbh | Vorrichtung und Verfahren zur Strukturanalyse und Detektion von komplexen Glykostrukturen |
EP1709443A2 (fr) | 2003-12-18 | 2006-10-11 | Procognia, Ltd. | Procede d'analyse d'une glycomolecule |
CA2657458A1 (fr) | 2006-07-11 | 2008-01-17 | Procognia (Israel) Ltd | Procede et essai pour la detection d'un motif de glycosylation liee a l'etat de cellules |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI852545L (fi) * | 1984-06-29 | 1985-12-30 | Ortho Diagnostic Systems Inc | Sandwichanalys av antikroppslektin. |
US5100778A (en) * | 1989-10-03 | 1992-03-31 | Monsanto Company | Oligosaccharide sequencing |
-
2000
- 2000-11-03 JP JP2001581120A patent/JP2004506874A/ja not_active Withdrawn
- 2000-11-03 EP EP00980286A patent/EP1281082A1/fr not_active Withdrawn
- 2000-11-03 WO PCT/US2000/030402 patent/WO2001084147A1/fr not_active Application Discontinuation
- 2000-11-03 CA CA002407272A patent/CA2407272A1/fr not_active Abandoned
- 2000-11-03 AU AU2001217569A patent/AU2001217569A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2004506874A (ja) | 2004-03-04 |
WO2001084147A1 (fr) | 2001-11-08 |
AU2001217569A1 (en) | 2001-11-12 |
EP1281082A1 (fr) | 2003-02-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |