CA2395187A1 - Molecular imprinting compositions and methods for binding and analyzing macromolecules - Google Patents

Molecular imprinting compositions and methods for binding and analyzing macromolecules Download PDF

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Publication number
CA2395187A1
CA2395187A1 CA002395187A CA2395187A CA2395187A1 CA 2395187 A1 CA2395187 A1 CA 2395187A1 CA 002395187 A CA002395187 A CA 002395187A CA 2395187 A CA2395187 A CA 2395187A CA 2395187 A1 CA2395187 A1 CA 2395187A1
Authority
CA
Canada
Prior art keywords
imprint
macromolecule
template molecule
macromolecules
template
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002395187A
Other languages
English (en)
French (fr)
Inventor
Chin-Shiou Huang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aspira Biosystems Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/507,300 external-priority patent/US6458599B1/en
Application filed by Individual filed Critical Individual
Publication of CA2395187A1 publication Critical patent/CA2395187A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/268—Polymers created by use of a template, e.g. molecularly imprinted polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/06—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing polymers
    • B01J31/063—Polymers comprising a characteristic microstructure
    • B01J31/067—Molecularly imprinted polymers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00664—Three-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00677—Ex-situ synthesis followed by deposition on the substrate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2600/00—Assays involving molecular imprinted polymers/polymers created around a molecular template

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Materials Engineering (AREA)
  • Food Science & Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Chemical Treatment Of Metals (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Shaping Of Tube Ends By Bending Or Straightening (AREA)
  • Dental Preparations (AREA)
  • Cosmetics (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
CA002395187A 2000-02-18 2001-02-16 Molecular imprinting compositions and methods for binding and analyzing macromolecules Abandoned CA2395187A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US50729900A 2000-02-18 2000-02-18
US09/507,300 US6458599B1 (en) 2000-02-18 2000-02-18 Compositions and methods for capturing, isolating, detecting, analyzing and quantifying macromolecules
US09/507,300 2000-02-18
US09/507,299 2000-02-18
US20308200P 2000-05-09 2000-05-09
US60/203,082 2000-05-09
PCT/US2001/005125 WO2001061355A1 (en) 2000-02-18 2001-02-16 Molecular impriniting compositions and methods for binding and analyzing macromolecules

Publications (1)

Publication Number Publication Date
CA2395187A1 true CA2395187A1 (en) 2001-08-23

Family

ID=27394506

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002395187A Abandoned CA2395187A1 (en) 2000-02-18 2001-02-16 Molecular imprinting compositions and methods for binding and analyzing macromolecules
CA002398999A Abandoned CA2398999A1 (en) 2000-02-18 2001-02-16 Compositions and methods for surface imprinting

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002398999A Abandoned CA2398999A1 (en) 2000-02-18 2001-02-16 Compositions and methods for surface imprinting

Country Status (9)

Country Link
EP (2) EP1255998A4 (enExample)
JP (2) JP2003525320A (enExample)
AT (1) ATE408639T1 (enExample)
AU (2) AU2001241531A1 (enExample)
CA (2) CA2395187A1 (enExample)
DE (1) DE60135831D1 (enExample)
IL (2) IL151217A0 (enExample)
NO (1) NO20023811L (enExample)
WO (2) WO2001061355A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210369647A1 (en) * 2015-12-21 2021-12-02 Mohamed Abdel-Rehim Micro-solid phase extraction

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458599B1 (en) 2000-02-18 2002-10-01 Aspira Biosystems, Inc. Compositions and methods for capturing, isolating, detecting, analyzing and quantifying macromolecules
US7105289B2 (en) 2001-04-11 2006-09-12 Aspira Biosystems, Inc. Inverse emulsion methods of making polymeric imprint beads
SE0300244D0 (sv) * 2003-01-30 2003-01-30 Mip Technologies Ab Forsknings Molecularly imprinted polymers for extraction of components from foodstuffs
JP4793816B2 (ja) * 2003-03-14 2011-10-12 独立行政法人産業技術総合研究所 マクロ分子識別ポリマーの製造方法
US7598087B2 (en) * 2004-01-07 2009-10-06 The Research Foundation Of State University Of New York Protein imprinted polymers with integrated emission sites
US9035025B2 (en) 2004-01-30 2015-05-19 Mip Technologies Ab Molecularly imprinted surfaces using surface-bound peptides
JP2006257170A (ja) * 2005-03-15 2006-09-28 Hokkaido Univ 微細多孔構造の形成方法およびその利用
JP5021183B2 (ja) 2005-05-20 2012-09-05 アークレイ株式会社 タンパク質固定化膜および固定化方法、ならびにバイオセンサ
DK1893979T3 (da) * 2005-06-22 2011-11-21 Adhesives Res Inc Molekylært præget polymer samt dens anvendelse i diagnostiske indretninger
FR2887885B1 (fr) 2005-07-04 2007-09-14 Polyintell Sarl Empreintes moleculaires a capacite de reconnaissance amelioree, leur procede de preparation et leur utilisation
JP4547324B2 (ja) * 2005-11-24 2010-09-22 シャープ株式会社 タンパク質認識構造体、タンパク質認識基板、及びこれらの製造方法
JP4925756B2 (ja) * 2006-07-19 2012-05-09 シャープ株式会社 タンパク質認識構造体、タンパク質認識基板、及びこれらの製造方法
JP4853971B2 (ja) * 2007-07-18 2012-01-11 国立大学法人神戸大学 標的分子のセンシングチップの作製方法
EP2212020B1 (en) * 2007-11-12 2018-07-04 Sellergren, Börje Imprinted polymers with affinity for phosphorylated peptides and proteins
JP2008111854A (ja) * 2008-01-24 2008-05-15 Toshiba Corp 分子認識センサ
JP4724188B2 (ja) * 2008-01-24 2011-07-13 株式会社東芝 分子認識センサ
JP2008151801A (ja) * 2008-01-24 2008-07-03 Toshiba Corp 分子認識センサ
JP5099074B2 (ja) * 2009-05-11 2012-12-12 株式会社豊田中央研究所 ターゲット分子の選択的吸着領域を有する吸着用担体及びその製造方法
CN101962824A (zh) * 2010-09-21 2011-02-02 福建师范大学 基于电纺丝技术制备的柚皮苷水相高效分离印迹纤维的方法
TWI450961B (zh) * 2011-12-16 2014-09-01 Mackay Memorial Hospital A thin film with a fixed phase of C-reactive protein and its application to the susceptor wafer system
WO2014178081A2 (en) * 2013-04-30 2014-11-06 Zim Laboratories Limited Molecular traps for certain undesirable materials
CN104075925B (zh) * 2014-07-22 2016-08-17 中国科学院烟台海岸带研究所 一种基于量子点的蛋白质核壳印迹微球的制备方法
CN106565915B (zh) * 2016-10-25 2018-10-09 江苏大学 一种双温敏型介孔印迹聚合物的制备方法
CN117165646B (zh) * 2023-08-25 2025-08-29 广州菲勒生物科技有限公司 一种胶原三肽组合物及其纯化方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8900130L (sv) * 1989-01-16 1990-07-17 Klaus Mosbach Konceptet att med hjaelp av molekylavtrycksmetoden framstaella konstgjorda antikroppar genom imprinting av t ex antigener samt att framstaella konstgjorda entzymer genom imprintning med transition state analoger
US5310648A (en) * 1991-02-01 1994-05-10 California Institute Of Technology Composition of matter comprising an imprinted matrix exhibiting selective binding interactions through chelated metals
US5587273A (en) * 1993-01-21 1996-12-24 Advanced Microbotics Corporation Molecularly imprinted materials, method for their preparation and devices employing such materials
ATE246212T1 (de) * 1995-05-26 2003-08-15 Igen Inc Molekular geprägten perl polymere und stabilisierte suspensionspolymerisation von diesen in perfluorkohlstoff flussigkeiten
US5728296A (en) * 1996-03-20 1998-03-17 Bio-Rad Laboratories, Inc. Selective recognition of solutes in chromatographic media by artificially created affinity
US6057377A (en) * 1998-10-30 2000-05-02 Sandia Corporation Molecular receptors in metal oxide sol-gel materials prepared via molecular imprinting

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210369647A1 (en) * 2015-12-21 2021-12-02 Mohamed Abdel-Rehim Micro-solid phase extraction

Also Published As

Publication number Publication date
IL151217A0 (en) 2003-04-10
WO2001061354A1 (en) 2001-08-23
EP1261873B1 (en) 2008-09-17
ATE408639T1 (de) 2008-10-15
JP2003525320A (ja) 2003-08-26
JP2003529634A (ja) 2003-10-07
CA2398999A1 (en) 2001-08-23
DE60135831D1 (de) 2008-10-30
EP1261873A4 (en) 2006-03-15
EP1261873A1 (en) 2002-12-04
WO2001061355A1 (en) 2001-08-23
AU2001238433A1 (en) 2001-08-27
EP1255998A1 (en) 2002-11-13
AU2001241531A1 (en) 2001-08-27
IL151218A0 (en) 2003-04-10
NO20023811D0 (no) 2002-08-12
NO20023811L (no) 2002-10-14
EP1255998A4 (en) 2006-03-15

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued