CA2393200C - Methods for targeting cells that express fibroblast growth receptor-3 or-2 - Google Patents
Methods for targeting cells that express fibroblast growth receptor-3 or-2 Download PDFInfo
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- CA2393200C CA2393200C CA2393200A CA2393200A CA2393200C CA 2393200 C CA2393200 C CA 2393200C CA 2393200 A CA2393200 A CA 2393200A CA 2393200 A CA2393200 A CA 2393200A CA 2393200 C CA2393200 C CA 2393200C
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/642—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| US45297799A | 1999-12-02 | 1999-12-02 | |
| US09/452,977 | 1999-12-02 | ||
| PCT/US2000/032380 WO2001039788A2 (en) | 1999-12-02 | 2000-11-28 | Methods for targeting cells that express fibroblast growth receptor-3 or-2 |
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| CA2393200A1 CA2393200A1 (en) | 2001-06-07 |
| CA2393200C true CA2393200C (en) | 2011-07-12 |
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| CA2393200A Expired - Fee Related CA2393200C (en) | 1999-12-02 | 2000-11-28 | Methods for targeting cells that express fibroblast growth receptor-3 or-2 |
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| EP (1) | EP1234033B1 (de) |
| JP (2) | JP5209161B2 (de) |
| AT (1) | ATE539157T1 (de) |
| AU (1) | AU1804201A (de) |
| CA (1) | CA2393200C (de) |
| ES (1) | ES2377935T3 (de) |
| WO (1) | WO2001039788A2 (de) |
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| US20050043234A1 (en) | 1996-10-16 | 2005-02-24 | Deisher Theresa A. | Novel FGF homologs |
| IL139380A0 (en) | 2000-10-31 | 2001-11-25 | Prochon Biotech Ltd | Active variants of fibroblast growth factor |
| US7157277B2 (en) | 2001-11-28 | 2007-01-02 | Neose Technologies, Inc. | Factor VIII remodeling and glycoconjugation of Factor VIII |
| US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| IL149562A0 (en) | 2002-05-09 | 2002-11-10 | Prochon Ltd | Fgf variants and methods for use thereof |
| AU2003279835B2 (en) | 2002-10-07 | 2009-09-10 | Zymogenetics, Inc. | Methods of administering FGF18 |
| US20040229292A1 (en) * | 2002-11-26 | 2004-11-18 | Sebastiano Cavallaro | Use of FGF-18 in the diagnosis and treatment of memory disorders |
| US7803777B2 (en) | 2003-03-14 | 2010-09-28 | Biogenerix Ag | Branched water-soluble polymers and their conjugates |
| US8791070B2 (en) | 2003-04-09 | 2014-07-29 | Novo Nordisk A/S | Glycopegylated factor IX |
| MXPA05010773A (es) | 2003-04-09 | 2005-12-12 | Neose Technologies Inc | Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos. |
| US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
| US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| WO2005012484A2 (en) | 2003-07-25 | 2005-02-10 | Neose Technologies, Inc. | Antibody-toxin conjugates |
| US8633157B2 (en) | 2003-11-24 | 2014-01-21 | Novo Nordisk A/S | Glycopegylated erythropoietin |
| US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
| US20060040856A1 (en) | 2003-12-03 | 2006-02-23 | Neose Technologies, Inc. | Glycopegylated factor IX |
| NZ548123A (en) | 2004-01-08 | 2010-05-28 | Novo Nordisk As | O-linked glycosylation of peptides |
| US20060009389A1 (en) | 2004-07-06 | 2006-01-12 | Moore Emma E | Pharmaceutical composition comprising FGF18 and IL-1 antagonist and method of use |
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| US5637677A (en) | 1987-07-16 | 1997-06-10 | The Trustees Of The University Of Pennsylvania | Biologically active compounds and methods of constructing and using the same |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5191067A (en) * | 1989-04-27 | 1993-03-02 | The Salk Institute For Biological Studies | Fibroblast growth factor conjugates |
| US5208146A (en) | 1990-11-05 | 1993-05-04 | The Regents Of The University Of California | Murine monoclonal anti-idiotype antibodies |
| US5911995A (en) * | 1994-08-19 | 1999-06-15 | Regents Of The University Of Minnesota | EGF-genistein conjugates for the treatment of cancer |
| FR2742662B1 (fr) * | 1995-12-21 | 1998-01-23 | Centre Nat Rech Scient | Anticorps anti-idiotypiques du facteur de croissance endotheliale vasculaire et leur utilisation comme medicaments |
| PT931148E (pt) * | 1996-10-16 | 2006-06-30 | Zymogenetics Inc | Homologos do factor de crescimento fibroblastico |
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- 2000-11-28 AU AU18042/01A patent/AU1804201A/en not_active Abandoned
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- 2000-11-28 EP EP00980829A patent/EP1234033B1/de not_active Expired - Lifetime
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| ES2377935T3 (es) | 2012-04-03 |
| AU1804201A (en) | 2001-06-12 |
| JP5209161B2 (ja) | 2013-06-12 |
| WO2001039788A2 (en) | 2001-06-07 |
| EP1234033A2 (de) | 2002-08-28 |
| JP2003515567A (ja) | 2003-05-07 |
| ATE539157T1 (de) | 2012-01-15 |
| JP2011140520A (ja) | 2011-07-21 |
| WO2001039788A3 (en) | 2002-01-31 |
| EP1234033B1 (de) | 2011-12-28 |
| CA2393200A1 (en) | 2001-06-07 |
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