CA2384806A1 - Use of replication-deficient adenoviral vector to boost cd8+ t cell immune response to antigen - Google Patents
Use of replication-deficient adenoviral vector to boost cd8+ t cell immune response to antigen Download PDFInfo
- Publication number
- CA2384806A1 CA2384806A1 CA002384806A CA2384806A CA2384806A1 CA 2384806 A1 CA2384806 A1 CA 2384806A1 CA 002384806 A CA002384806 A CA 002384806A CA 2384806 A CA2384806 A CA 2384806A CA 2384806 A1 CA2384806 A1 CA 2384806A1
- Authority
- CA
- Canada
- Prior art keywords
- antigen
- epitope
- administration
- individual
- boosting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9922361.2 | 1999-09-21 | ||
| GBGB9922361.2A GB9922361D0 (en) | 1999-09-21 | 1999-09-21 | Generating an immune response to an antigen |
| PCT/GB2000/003601 WO2001021201A2 (en) | 1999-09-21 | 2000-09-20 | Use of replication-deficient adenoviral vector to boost cd8+ t cell immune response to antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2384806A1 true CA2384806A1 (en) | 2001-03-29 |
Family
ID=10861351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002384806A Abandoned CA2384806A1 (en) | 1999-09-21 | 2000-09-20 | Use of replication-deficient adenoviral vector to boost cd8+ t cell immune response to antigen |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP1612269A1 (enExample) |
| JP (1) | JP2003509470A (enExample) |
| CN (1) | CN1391609A (enExample) |
| AT (1) | ATE295421T1 (enExample) |
| AU (1) | AU762894B2 (enExample) |
| BR (1) | BR0014138A (enExample) |
| CA (1) | CA2384806A1 (enExample) |
| DE (1) | DE60020136T2 (enExample) |
| DK (1) | DK1214416T3 (enExample) |
| ES (1) | ES2241653T3 (enExample) |
| GB (1) | GB9922361D0 (enExample) |
| WO (1) | WO2001021201A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9711957D0 (en) | 1997-06-09 | 1997-08-06 | Isis Innovation | Methods and reagents for vaccination |
| EP1200622A4 (en) | 1999-07-06 | 2004-12-22 | Merck & Co Inc | HIV VACCINE FROM AN ADENOVIRUS CARRYING THE GAG GENE |
| US6733993B2 (en) | 2000-09-15 | 2004-05-11 | Merck & Co., Inc. | Enhanced first generation adenovirus vaccines expressing codon optimized HIV1-gag, pol, nef and modifications |
| GB0118532D0 (en) * | 2001-07-30 | 2001-09-19 | Isis Innovation | Materials and methods relating to improved vaccination strategies |
| WO2003097087A1 (en) * | 2002-05-20 | 2003-11-27 | Japan Science And Technology Agency | Bcg vaccine and utilization thereof |
| US20080153083A1 (en) | 2003-10-23 | 2008-06-26 | Crucell Holland B.V. | Settings for recombinant adenoviral-based vaccines |
| EP1553983A2 (en) | 2002-10-23 | 2005-07-20 | Crucell Holland B.V. | New settings for recombinant adenoviral-based vaccines |
| CN100410382C (zh) * | 2006-08-18 | 2008-08-13 | 上海交通大学医学院 | 一种可诱生细胞免疫应答的共表达载体和真核表达载体 |
| AU2007322075B2 (en) * | 2006-11-17 | 2013-07-25 | Genetronics, Inc. | Methods of enhancing immune response using electroporation-assisted vaccination and boosting |
| GB0706912D0 (en) * | 2007-04-10 | 2007-05-16 | Isis Innovation | Novel viral vaccines |
| GB0706914D0 (en) | 2007-04-10 | 2007-05-16 | Isis Innovation | Novel adenovirus vectors |
| JP5710254B2 (ja) * | 2007-09-14 | 2015-04-30 | アンスティテュ・パストゥールＩｎｓｔｉｔｕｔ Ｐａｓｔｅｕｒ | 外来エピトープを含む組換え偽ウイルスの発現および分泌を可能とするポリヌクレオチド、それらの製造および使用 |
| GB0823497D0 (en) * | 2008-12-24 | 2009-01-28 | Isis Innovation | Immunogenic composition and use thereof |
| PT2912183T (pt) * | 2012-10-28 | 2020-06-05 | Bavarian Nordic As | Promotor pr13.5 para respostas robustas de células t e anticorpos |
| KR20230166145A (ko) | 2017-03-15 | 2023-12-06 | 옥스포드 바이오메디카(유케이) 리미티드 | 방법 |
| MX2022004484A (es) * | 2019-10-16 | 2022-07-19 | Cancer Research Tech Ltd | Vector para el tratamiento de cancer. |
| US20230310591A1 (en) | 2021-12-07 | 2023-10-05 | Vaccitech (Uk) Limited | Vaccine Boost Methods and Compositions |
| WO2024218165A1 (en) | 2023-04-17 | 2024-10-24 | Barinthus Biotherapeutics (Uk) Limited | Hpv viral vector vaccine |
-
1999
- 1999-09-21 GB GBGB9922361.2A patent/GB9922361D0/en not_active Ceased
-
2000
- 2000-09-20 CN CN00815933A patent/CN1391609A/zh active Pending
- 2000-09-20 WO PCT/GB2000/003601 patent/WO2001021201A2/en not_active Ceased
- 2000-09-20 CA CA002384806A patent/CA2384806A1/en not_active Abandoned
- 2000-09-20 AT AT00960857T patent/ATE295421T1/de not_active IP Right Cessation
- 2000-09-20 EP EP05009308A patent/EP1612269A1/en not_active Withdrawn
- 2000-09-20 DK DK00960857T patent/DK1214416T3/da active
- 2000-09-20 ES ES00960857T patent/ES2241653T3/es not_active Expired - Lifetime
- 2000-09-20 EP EP00960857A patent/EP1214416B1/en not_active Revoked
- 2000-09-20 DE DE60020136T patent/DE60020136T2/de not_active Revoked
- 2000-09-20 AU AU73024/00A patent/AU762894B2/en not_active Ceased
- 2000-09-20 JP JP2001524625A patent/JP2003509470A/ja not_active Withdrawn
- 2000-09-20 BR BR0014138-0A patent/BR0014138A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1612269A1 (en) | 2006-01-04 |
| BR0014138A (pt) | 2002-05-21 |
| EP1214416A2 (en) | 2002-06-19 |
| AU762894B2 (en) | 2003-07-10 |
| CN1391609A (zh) | 2003-01-15 |
| WO2001021201A2 (en) | 2001-03-29 |
| EP1214416B1 (en) | 2005-05-11 |
| DE60020136T2 (de) | 2006-02-23 |
| DK1214416T3 (da) | 2005-08-29 |
| WO2001021201A3 (en) | 2001-10-18 |
| AU7302400A (en) | 2001-04-24 |
| JP2003509470A (ja) | 2003-03-11 |
| DE60020136D1 (de) | 2005-06-16 |
| ES2241653T3 (es) | 2005-11-01 |
| ATE295421T1 (de) | 2005-05-15 |
| GB9922361D0 (en) | 1999-11-24 |
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| FZDE | Discontinued |