CA2379836A1 - System for microvolume laser scanning cytometry - Google Patents

System for microvolume laser scanning cytometry Download PDF

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Publication number
CA2379836A1
CA2379836A1 CA002379836A CA2379836A CA2379836A1 CA 2379836 A1 CA2379836 A1 CA 2379836A1 CA 002379836 A CA002379836 A CA 002379836A CA 2379836 A CA2379836 A CA 2379836A CA 2379836 A1 CA2379836 A1 CA 2379836A1
Authority
CA
Canada
Prior art keywords
particles
sample
pixel values
light
threshold
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002379836A
Other languages
English (en)
French (fr)
Inventor
Aaron B. Kantor
Louis J. Dietz
Chih-Hua Chung
Scott Norton
Shalom Tsur
Ian Walton
Byron Lee
James L. Winkler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alavita Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2379836A1 publication Critical patent/CA2379836A1/en
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • G01N15/1433Signal processing using image recognition
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00Pattern recognition
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00Scenes; Scene-specific elements
    • G06V20/60Type of objects
    • G06V20/69Microscopic objects, e.g. biological cells or cellular parts
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484Optical investigation techniques, e.g. flow cytometry microstructural devices

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Data Mining & Analysis (AREA)
  • Multimedia (AREA)
  • General Engineering & Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Evolutionary Computation (AREA)
  • Signal Processing (AREA)
  • Artificial Intelligence (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002379836A 1999-07-21 2000-04-26 System for microvolume laser scanning cytometry Abandoned CA2379836A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14479899P 1999-07-21 1999-07-21
US60/144,798 1999-07-21
PCT/US2000/011133 WO2001008081A1 (en) 1999-07-21 2000-04-26 System for microvolume laser scanning cytometry

Publications (1)

Publication Number Publication Date
CA2379836A1 true CA2379836A1 (en) 2001-02-01

Family

ID=22510184

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002379836A Abandoned CA2379836A1 (en) 1999-07-21 2000-04-26 System for microvolume laser scanning cytometry

Country Status (8)

Country Link
EP (1) EP1203339A4 (no)
JP (1) JP2003505707A (no)
KR (1) KR20020013970A (no)
AU (1) AU4491100A (no)
CA (1) CA2379836A1 (no)
MX (1) MXPA01013398A (no)
NZ (1) NZ516637A (no)
WO (1) WO2001008081A1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7192778B2 (en) 1999-10-06 2007-03-20 Natan Michael J Surface enhanced spectroscopy-active composite nanoparticles
US8497131B2 (en) 1999-10-06 2013-07-30 Becton, Dickinson And Company Surface enhanced spectroscopy-active composite nanoparticles comprising Raman-active reporter molecules
WO2002079764A1 (en) 2001-01-26 2002-10-10 Nanoplex Technologies, Inc. Surface-enhanced spectroscopy-active sandwich nanoparticles
US6924114B2 (en) 2000-09-20 2005-08-02 Surromed, Inc. Method for monitoring resting and activated platelets in unfixed blood samples
US7572642B2 (en) 2001-04-18 2009-08-11 Ambrigen, Llc Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns
WO2002090947A2 (de) * 2001-05-07 2002-11-14 Deutsches Krebsforschungszentrum Stiftung D. Öffentl. Rechts Fluoreszenzfluktuationsmikroskop, -messmodul bzw.-scanmodul und verfahren zur fluoreszenzfluktuationsmessung sowie verfahren und vorrichtung zur justage eines fluoreszenzfluktuationsmikroskops
JP2008545959A (ja) * 2005-05-25 2008-12-18 スティフテルセン ウニヴェルジテーツフォルスクニング ベルゲン 顕微鏡装置および薬品、物理療法と生物学的危険物質のためのふるい分け(screening)方法
US8409863B2 (en) 2005-12-14 2013-04-02 Becton, Dickinson And Company Nanoparticulate chemical sensors using SERS
US7796251B2 (en) * 2006-03-22 2010-09-14 Itt Manufacturing Enterprises, Inc. Method, apparatus and system for rapid and sensitive standoff detection of surface contaminants
JP4909254B2 (ja) * 2007-12-26 2012-04-04 日本電信電話株式会社 浮遊粒子状物質測定装置
JP5550719B2 (ja) * 2009-04-27 2014-07-16 イーアイ・スペクトラ・エルエルシー ピペット機器
US9746412B2 (en) 2012-05-30 2017-08-29 Iris International, Inc. Flow cytometer
EP2861956B1 (en) * 2012-05-30 2024-01-24 Iris International, Inc. Flow cytometer
WO2020141463A2 (en) * 2019-01-03 2020-07-09 Pixcell Medical Technologies Ltd. Systems and methods for analyzing a fluid sample

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE455646B (sv) * 1984-10-22 1988-07-25 Radians Innova Ab Fluorescensanordning
US5107422A (en) * 1989-10-02 1992-04-21 Kamentsky Louis A Method and apparatus for measuring multiple optical properties of biological specimens
US5127730A (en) * 1990-08-10 1992-07-07 Regents Of The University Of Minnesota Multi-color laser scanning confocal imaging system
JPH0599912A (ja) * 1991-10-11 1993-04-23 Union Shokai:Kk アナログフイルター装置
AU671984B2 (en) * 1992-02-18 1996-09-19 Neopath, Inc. Method for identifying objects using data processing techniques
US5377003A (en) * 1992-03-06 1994-12-27 The United States Of America As Represented By The Department Of Health And Human Services Spectroscopic imaging device employing imaging quality spectral filters
US5889881A (en) * 1992-10-14 1999-03-30 Oncometrics Imaging Corp. Method and apparatus for automatically detecting malignancy-associated changes
US5556764A (en) * 1993-02-17 1996-09-17 Biometric Imaging, Inc. Method and apparatus for cell counting and cell classification
US5456252A (en) * 1993-09-30 1995-10-10 Cedars-Sinai Medical Center Induced fluorescence spectroscopy blood perfusion and pH monitor and method
JP3474612B2 (ja) * 1993-12-03 2003-12-08 浜松ホトニクス株式会社 光検出装置
JPH08313348A (ja) * 1995-05-16 1996-11-29 Kanagawa Kagaku Gijutsu Akad 赤外光時間応答測定装置
US5582705A (en) * 1995-05-19 1996-12-10 Iowa State University Research Foundation, Inc. Multiplexed capillary electrophoresis system

Also Published As

Publication number Publication date
AU4491100A (en) 2001-02-13
MXPA01013398A (es) 2003-03-27
JP2003505707A (ja) 2003-02-12
WO2001008081A1 (en) 2001-02-01
NZ516637A (en) 2003-08-29
EP1203339A4 (en) 2006-09-13
EP1203339A1 (en) 2002-05-08
KR20020013970A (ko) 2002-02-21

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Legal Events

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FZDE Discontinued