CA2376357A1 - .mu.o-conopeptides and their use as local anesthetics - Google Patents

.mu.o-conopeptides and their use as local anesthetics Download PDF

Info

Publication number
CA2376357A1
CA2376357A1 CA002376357A CA2376357A CA2376357A1 CA 2376357 A1 CA2376357 A1 CA 2376357A1 CA 002376357 A CA002376357 A CA 002376357A CA 2376357 A CA2376357 A CA 2376357A CA 2376357 A1 CA2376357 A1 CA 2376357A1
Authority
CA
Canada
Prior art keywords
tyr
cys
lys
ile
leu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002376357A
Other languages
English (en)
French (fr)
Inventor
Baldomero M. Olivera
J. Michael Mcintosh
R. Tyler Mccabe
James E. Garrett
Richard T. Layer
John D. Wagstaff
Robert M. Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cognetix Inc
University of Utah Research Foundation Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2376357A1 publication Critical patent/CA2376357A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA002376357A 1999-06-10 2000-06-09 .mu.o-conopeptides and their use as local anesthetics Abandoned CA2376357A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13850799P 1999-06-10 1999-06-10
US60/138,507 1999-06-10
PCT/US2000/015779 WO2000076532A1 (en) 1999-06-10 2000-06-09 νO-CONOPEPTIDES AND THEIR USE AS LOCAL ANESTHETICS

Publications (1)

Publication Number Publication Date
CA2376357A1 true CA2376357A1 (en) 2000-12-21

Family

ID=22482336

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002376357A Abandoned CA2376357A1 (en) 1999-06-10 2000-06-09 .mu.o-conopeptides and their use as local anesthetics

Country Status (5)

Country Link
EP (1) EP1185286A4 (enExample)
JP (1) JP2003501109A (enExample)
AU (1) AU5474200A (enExample)
CA (1) CA2376357A1 (enExample)
WO (1) WO2000076532A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003533178A (ja) 1999-12-30 2003-11-11 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション O−スーパーファミリー・コノトキシンペプチド
GB0011202D0 (en) * 2000-05-09 2000-06-28 Kci Licensing Inc Abdominal wound dressing
WO2002007756A1 (en) * 2000-07-20 2002-01-31 Cognetix, Inc. MuO-CONOPEPTIDES AND THEIR USE AS LOCAL ANESTHETICS
WO2002007678A2 (en) * 2000-07-21 2002-01-31 University Of Utah Research Foundation Mu-conopeptides
ATE528315T1 (de) * 2006-08-17 2011-10-15 Eribis Pharmaceuticals Ab Cardioprotektive verbindungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5719264A (en) * 1994-10-07 1998-02-17 Univ. Of Utah Research Foundation Conotoxin peptides
EP0821694A4 (en) * 1995-04-17 1999-04-14 Univ Utah Res Found CONOTOXIN PEPTIDE
FR2785613B1 (fr) * 1998-11-10 2001-01-05 Commissariat Energie Atomique Conotoxine isolee a partir du venin de conus ermineus, ses analogues et ses applications

Also Published As

Publication number Publication date
AU5474200A (en) 2001-01-02
EP1185286A1 (en) 2002-03-13
JP2003501109A (ja) 2003-01-14
EP1185286A4 (en) 2004-09-08
WO2000076532A1 (en) 2000-12-21

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Legal Events

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EEER Examination request
FZDE Dead