CA2373603A1 - Composes diphenylethylene innovants - Google Patents
Composes diphenylethylene innovants Download PDFInfo
- Publication number
- CA2373603A1 CA2373603A1 CA002373603A CA2373603A CA2373603A1 CA 2373603 A1 CA2373603 A1 CA 2373603A1 CA 002373603 A CA002373603 A CA 002373603A CA 2373603 A CA2373603 A CA 2373603A CA 2373603 A1 CA2373603 A1 CA 2373603A1
- Authority
- CA
- Canada
- Prior art keywords
- ome
- compound
- hydrogen
- composition according
- diabetes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
- C07C15/40—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts substituted by unsaturated carbon radicals
- C07C15/50—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts substituted by unsaturated carbon radicals polycyclic non-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
- C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1999/011001 WO2000069430A1 (fr) | 1999-05-18 | 1999-05-18 | Composes diphenylethylene innovants |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2373603A1 true CA2373603A1 (fr) | 2000-11-23 |
Family
ID=22272785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002373603A Abandoned CA2373603A1 (fr) | 1999-05-18 | 1999-05-18 | Composes diphenylethylene innovants |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1178788A4 (fr) |
JP (1) | JP2002544227A (fr) |
KR (1) | KR100598638B1 (fr) |
CN (1) | CN1194674C (fr) |
AU (1) | AU778767C (fr) |
CA (1) | CA2373603A1 (fr) |
HK (1) | HK1046642B (fr) |
MX (1) | MXPA01011760A (fr) |
WO (1) | WO2000069430A1 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7323496B2 (en) | 1999-11-08 | 2008-01-29 | Theracos, Inc. | Compounds for treatment of inflammation, diabetes and related disorders |
JP2003521500A (ja) * | 2000-02-04 | 2003-07-15 | カリックス セラピューティックス インコーポレイテッド | 新規ジフェニルエチレン化合物 |
US6552085B2 (en) | 2000-08-16 | 2003-04-22 | Insmed Incorporated | Compositions containing hypoglycemically active stilbenoids |
US6410596B1 (en) * | 2000-08-16 | 2002-06-25 | Insmed Incorporated | Compositions containing hypoglycemically active stillbenoids |
US7384920B2 (en) | 2001-07-26 | 2008-06-10 | Institute Of Radiation Medicine, Academy Of Military Medical Sciences, Pla | Use of stilbene compounds in the manufacture of medicament for the prevention and treatment of diabetes or retrovirus-associated diseases |
JP4781580B2 (ja) * | 2001-09-26 | 2011-09-28 | 日本メナード化粧品株式会社 | コラゲナーゼ阻害剤 |
JP2007527418A (ja) | 2003-12-29 | 2007-09-27 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 肥満及びインシュリン耐性障害を治療又は防止するための組成物 |
US8017634B2 (en) | 2003-12-29 | 2011-09-13 | President And Fellows Of Harvard College | Compositions for treating obesity and insulin resistance disorders |
CN1723884A (zh) * | 2004-07-21 | 2006-01-25 | 中国人民解放军军事医学科学院放射医学研究所 | 顺式-1,2-取代的二苯乙烯衍生物用于制备治疗或预防糖尿病的药物的用途 |
WO2006138418A2 (fr) | 2005-06-14 | 2006-12-28 | President And Fellows Of Harvard College | Amelioration de la performance cognitive avec des activateurs de sirtuine |
CN100384801C (zh) * | 2006-06-23 | 2008-04-30 | 中国科学院广州化学研究所 | (e)-3,5-二甲氧基-4'-羟基二苯乙烯的合成方法 |
FR2904311B1 (fr) | 2006-07-28 | 2013-01-11 | Clariant Specialty Fine Chem F | Nouveau procede de synthese de derives (e) stilbeniques perm permettant d'obtenir le resveratrol et le piceatannol |
FR2921921B1 (fr) | 2007-10-03 | 2011-08-19 | Clariant Specialty Fine Chem F | Procede de synthese de composes polyhydroxystilbeniques. |
CN107324976B (zh) * | 2017-07-28 | 2020-06-16 | 安徽理工大学 | 一种制备(E)-β-烷基苯乙烯类化合物的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5314693A (en) * | 1992-02-07 | 1994-05-24 | Kioritz Corporation | Pest control chemicals against pine wood nematodes |
US5430062A (en) * | 1992-05-21 | 1995-07-04 | Research Corporation Technologies, Inc. | Stilbene derivatives as anticancer agents |
US5770620A (en) * | 1995-06-19 | 1998-06-23 | Ontogen Corporation | Aryl acrylic acid derivatives useful as protein tyrosine phosphatase inhibitors |
US5827898A (en) * | 1996-10-07 | 1998-10-27 | Shaman Pharmaceuticals, Inc. | Use of bisphenolic compounds to treat type II diabetes |
FR2778337B1 (fr) * | 1998-05-05 | 2001-08-31 | Inst Nat Sante Rech Med | Antagonistes des ligands du recepteur des arylhydrocarbures |
-
1999
- 1999-05-18 WO PCT/US1999/011001 patent/WO2000069430A1/fr active IP Right Grant
- 1999-05-18 KR KR1020017014590A patent/KR100598638B1/ko not_active IP Right Cessation
- 1999-05-18 MX MXPA01011760A patent/MXPA01011760A/es not_active IP Right Cessation
- 1999-05-18 CN CNB998166448A patent/CN1194674C/zh not_active Expired - Fee Related
- 1999-05-18 AU AU40857/99A patent/AU778767C/en not_active Ceased
- 1999-05-18 CA CA002373603A patent/CA2373603A1/fr not_active Abandoned
- 1999-05-18 EP EP99924332A patent/EP1178788A4/fr not_active Withdrawn
- 1999-05-18 JP JP2000617889A patent/JP2002544227A/ja active Pending
-
2002
- 2002-11-14 HK HK02108244.5A patent/HK1046642B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1178788A4 (fr) | 2005-08-10 |
CN1354659A (zh) | 2002-06-19 |
CN1194674C (zh) | 2005-03-30 |
AU4085799A (en) | 2000-12-05 |
HK1046642A1 (en) | 2003-01-24 |
EP1178788A1 (fr) | 2002-02-13 |
JP2002544227A (ja) | 2002-12-24 |
WO2000069430A1 (fr) | 2000-11-23 |
HK1046642B (zh) | 2005-11-25 |
KR100598638B1 (ko) | 2006-07-07 |
KR20020012220A (ko) | 2002-02-15 |
AU778767B2 (en) | 2004-12-23 |
AU778767C (en) | 2006-09-07 |
MXPA01011760A (es) | 2003-09-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |